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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_1765 [new locus tag: SAUSA300_RS09660 ]
  • pan locus tag?: SAUPAN004577000
  • symbol: epiC
  • pan gene symbol?: epiC
  • synonym:
  • product: lantibiotic epidermin biosynthesis protein EpiC

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_1765 [new locus tag: SAUSA300_RS09660 ]
  • symbol: epiC
  • product: lantibiotic epidermin biosynthesis protein EpiC
  • replicon: chromosome
  • strand: -
  • coordinates: 1949759..1951003
  • length: 1245
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGATTGATATGAATCTAATATTGAAGAAGAAGTTTCAAGAGATTTCAGAAGTAGATGAT
    TTCATTTCAAAAGCATCTACTGAAACCGATTATTTTGAACCTTCAACTTTATCACATGGT
    ATACCAGGTATCATTTTGTTTTTAGATGCTTATCAAAAAGTTTTCGATATTAATACTGAG
    CAAATTGTGCATAAGTACATCATGAAATTAGCACCATATTTACAGAGTGGTCAATATAAC
    AATTCTTTGTTTGGTGGACTTTCAGGTATTGCATTTTCAATGGATTTAGCATCGCAAAAT
    GGCAAAAATTATCAAAATATTTTAAATAATATTGATGGTCACATTGTAAATGAAATAGAA
    AATAAATTTGATCAAATATTACAAGAACCATTAAATCCATTAAATTATGATACTGTCAGT
    GGATTAGCTGGGATAGGGAGATATTTGCTAAATAGAGTAGATGAGAATGAATTTAATGTT
    AAAGCATTAAAAAGCATATTAGTATACTTTAAAGATATTCAATATTCTAAAAATAGCTGG
    GTAGTCCCACAAGAAAGTCAATTTTTAGAGTCTGATAAAAATTATTTTACTGAAGGTAAT
    ATCAATCTTGGCCTTGCACATGGAGTGCTAGGACCGATGTCTTTATTTGCATTATGCGTG
    ATTAAAGGAATTACGATTGAAAATCATCAGCACATATTAAAAGACATGTACAAATTTATC
    ATGGACGAAAAATTTTGTAACCACGAAAGATGGTTGCAGCGTTACGATTTAATTTCTGAA
    CGTAATCATTTCAATTTTATTCGGAATGGTTGGTGTTATGGCAATACGGGTGTAATGACG
    ACGTTGTTTTTAATCGGCCAAGCATTACAAGATGATGAAATAATTAAAATGTCTAAAAAA
    GTGATGCTACAAGTAGTAAATGATAAAGATGAAAATTTAATAAGTCCAACTATTTGTCAT
    GGATTGTCATCACAAATATTAATGTTAACAATTATGAATTTGAATTTTGAATTAAATGAA
    GTGTCTGATTATATCACTGTATTAATAAATAAACTGATTTCTCATTATAAGGAAGATTAT
    CTGGTGAATTTTATAGACATTAATGAAAATAAGCAAGATGTATTTAAAAGTAGGAAAGTT
    GGCCTTTTAGAAGGTGAATTAGGGGTCTATCTAACATTGATGACACTGAAAAATACAAAA
    ATTCTCAATGAAAAAAATTGGACCAATGCGTTTTTAATTAGCTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1245

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_1765 [new locus tag: SAUSA300_RS09660 ]
  • symbol: EpiC
  • description: lantibiotic epidermin biosynthesis protein EpiC
  • length: 414
  • theoretical pI: 5.15033
  • theoretical MW: 47645.4
  • GRAVY: -0.148309

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Toxin production and resistance type 2 lantibiotic biosynthesis protein LanM (TIGR03897; HMM-score: 60.8)
  • TheSEED  :
    • Lanthionine biosynthesis cyclase LanC
  • PFAM:
    6_Hairpin (CL0059) LANC_like; Lanthionine synthetase C-like protein (PF05147; HMM-score: 290.1)
    and 1 more
    no clan defined YppF; YppF-like protein (PF14178; HMM-score: 14.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001413
    • TAT(Tat/SPI): 0.000105
    • LIPO(Sec/SPII): 0.000432
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIDMNLILKKKFQEISEVDDFISKASTETDYFEPSTLSHGIPGIILFLDAYQKVFDINTEQIVHKYIMKLAPYLQSGQYNNSLFGGLSGIAFSMDLASQNGKNYQNILNNIDGHIVNEIENKFDQILQEPLNPLNYDTVSGLAGIGRYLLNRVDENEFNVKALKSILVYFKDIQYSKNSWVVPQESQFLESDKNYFTEGNINLGLAHGVLGPMSLFALCVIKGITIENHQHILKDMYKFIMDEKFCNHERWLQRYDLISERNHFNFIRNGWCYGNTGVMTTLFLIGQALQDDEIIKMSKKVMLQVVNDKDENLISPTICHGLSSQILMLTIMNLNFELNEVSDYITVLINKLISHYKEDYLVNFIDINENKQDVFKSRKVGLLEGELGVYLTLMTLKNTKILNEKNWTNAFLIS

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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