PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN004592000
• symbol^?: lukE
• synonym:
• description^?: gamma-hemolysin subunit A

  descriptions from strain specific annotations:

  • gamma-hemolysin subunit A
  • leukotoxin LukE
  • beta-channel forming cytolysin
  • leukocidin, E-subunit
  • leukocidin LukE precursor
  • gamma-hemolysin component A precursor
  • Leukocidin LukE
  • leukocidin-S subunit
  • leukotoxin, LukE
  • leukotoxin E subunit
  • leukotoxin S-subunit
  • pseudogene
• strand^?: -
• coordinates^?: 4829616..4830521
• synteny block^?: BlockID0035700
• occurrence^?: in 73% of 33 strains

⊟Orthologs

COL:
SACOL1881 (lukE)
N315:
SA1638 (lukE)
NCTC8325:
SAOUHSC_01955
Newman:
NWMN_1719 (lukE)
USA300_FPR3757:
SAUSA300_1769 (lukE)
04-02981:
SA2981_1775 (lukE)
08BA02176:
—
11819-97:
MS7_1825 (lukE)
6850:
RSAU_001675 (lukE)
71193:
—
ECT-R 2:
ECTR2_1653
ED133:
SAOV_1813c (lukE)
ED98:
SAAV_1829 (lukE)
HO 5096 0412:
—
JH1:
SaurJH1_1905
JH9:
SaurJH9_1871
JKD6008:
—
JKD6159:
SAA6159_01751 (lukE)
LGA251:
SARLGA251_17090 (hlgA)
M013:
—
MRSA252:
—
MSHR1132:
—
MSSA476:
SAS1749 (hlgA)
Mu3:
SAHV_1805 (lukE)
Mu50:
SAV1820 (lukE)
MW2:
MW1768 (lukE)
RF122:
SAB1687c (lukE)
ST398:
—
T0131:
SAT0131_01947 (recQ1)
TCH60:
—
TW20:
SATW20_18220 (hlgA)
USA300_TCH1516:
USA300HOU_1818 (lukE)
VC40:
SAVC_08365

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MFKKKMLAATLSVGLIAPLASPIQESRANTNIENIGDGAEVIKRTEDVSSKKWGVTQNVQ
  N315            MFKKKMLAATLSVGLIAPLASPIQESRANTNIENIGDGAEVIKRTEDVSSKKWGVTQNVQ
  NCTC8325        ----------MSVGLIAPLASPIQESRANTNIENIGDGAEVIKRTEDVSSKKWGVTQNVQ
  Newman          MFKKKMLAATLSVGLIAPLASPIQESRANTNIENIGDGAEVIKRTEDVSSKKWGVTQNVQ
  USA300_FPR3757  MFKKKMLAATLSVGLIAPLASPIQESRANTNIENIGDGAEVIKRTEDVSSKKWGVTQNVQ
                            :*************************************************
  
  COL             FDFVKDKKYNKDALIVKMQGFINSRTSFSDVKGSGYELTKRMIWPFQYNIGLTTKDPNVS
  N315            FDFVKDKKYNKDALIVKMQGFINSRTSFSDVKGSGYELTKRMIWPFQYNIGLTTKDPNVS
  NCTC8325        FDFVKDKKYNKDALIVKMQGFINSRTSFSDVKGSGYELTKRMIWPFQYNIGLTTKDPNVS
  Newman          FDFVKDKKYNKDALIVKMQGFINSRTSFSDVKGSGYELTKRMIWPFQYNIGLTTKDPNVS
  USA300_FPR3757  FDFVKDKKYNKDALIVKMQGFINSRTSFSDVKGSGYELTKRMIWPFQYNIGLTTKDPNVS
                  ************************************************************
  
  COL             LINYLPKNKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFNYSKTISYTQKSYVSEVDKQN
  N315            LINYLPKNKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFNYSKTISYTQKSYVSEVDKQN
  NCTC8325        LINYLPKNKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFNYSKTISYTQKSYVSEVDKQN
  Newman          LINYLPKNKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFNYSKTISYTQKSYVSEVDKQN
  USA300_FPR3757  LINYLPKNKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFNYSKTISYTQKSYVSEVDKQN
                  ************************************************************
  
  COL             SKSVKWGVKANEFVTPDGKKSAHDRYLFVQSPNGPTGSAREYFAPDNQLPPLVQSGFNPS
  N315            SKSVKWGVKANEFVTPDGKKSAHDRYLFVQSPNGPTGSAREYFAPDNQLPPLVQSGFNPS
  NCTC8325        SKSVKWGVKANEFVTPDGKKSAHDRYLFVQSPNGPTGSAREYFAPDNQLPPLVQSGFNPS
  Newman          SKSVKWGVKANEFVTPDGKKSAHDRYLFVQSPNGPTGSAREYFAPDNQLPPLVQSGFNPS
  USA300_FPR3757  SKSVKWGVKANEFVTPDGKKSAHDRYLFVQSPNGPTGSAREYFAPDNQLPPLVQSGFNPS
                  ************************************************************
  
  COL             FITTLSHEKGSSDTSEFEISYGRNLDITYATLFPRTGIYAERKHNAFVNRNFVVRYEVNW
  N315            FITTLSHEKGSSDTSEFEISYGRNLDITYATLFPRTGIYAERKHNAFVNRNFVVRYEVNW
  NCTC8325        FITTLSHEKGSSDTSEFEISYGRNLDITYATLFPRTGIYAERKHNAFVNRNFVVRYEVNW
  Newman          FITTLSHEKGSSDTSEFEISYGRNLDITYATLFPRTGIYAERKHNAFVNRNFVVRYEVNW
  USA300_FPR3757  FITTLSHEKGSSDTSEFEISYGRNLDITYATLFPRTGIYAERKHNAFVNRNFVVRYEVNW
                  ************************************************************
  
  COL             KTHEIKVKGHN
  N315            KTHEIKVKGHN
  NCTC8325        KTHEIKVKGHN
  Newman          KTHEIKVKGHN
  USA300_FPR3757  KTHEIKVKGHN
                  ***********