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⊟Summary[edit | edit source]
- pan ID?: SAUPAN004781000
- symbol?: airR
- synonym:
- description?: DNA-binding response regulator
- DNA-binding response regulator
- LuxR family DNA-binding response regulator
- response regulator transcription factor
- two-component response regulator
- two-component response regulator-like protein
- bacterial regulatory s, luxR family protein
- putative response regulator
- response regulator protein
- response regulator receiver
- two component LuxR family transcriptional regulator
- two-component response regulator protein
- two-component response regulator receiver protein
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 4991074..4991697
- synteny block?: BlockID0037130
- occurrence?: in 100% of 33 strains
airR: anaerobic iron-sulfur redox response regulator [1]
AirR has a DNA binding motif of: 5'-KAAMATNNAMAAAT-3' [2]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1804
08BA02176:
C248_1891
11819-97:
MS7_1853
6850:
RSAU_001707
71193:
ST398NM01_1914
ECT-R 2:
ECTR2_1690
ED133:
SAOV_1845
ED98:
SAAV_1867
HO 5096 0412:
SAEMRSA15_17530
JH1:
SaurJH1_1936
JH9:
SaurJH9_1902
JKD6008:
SAA6008_01805 (yhcR)
JKD6159:
SAA6159_01776 (yhcR)
LGA251:
SARLGA251_17310 (yhcR)
M013:
M013TW_1854
MRSA252:
SAR1939
MSHR1132:
SAMSHR1132_16940
MSSA476:
SAS1769
Mu3:
SAHV_1833 (yhcR)
Mu50:
SAV1848
MW2:
MW1789
RF122:
SAB1781c
ST398:
SAPIG1914
T0131:
SAT0131_01968
TCH60:
HMPREF0772_11296 (vraR2)
TW20:
SATW20_18420 (yhcR)
USA300_TCH1516:
USA300HOU_1842
VC40:
SAVC_08480
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPG
N315 MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPG
NCTC8325 MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPG
Newman MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPG
USA300_FPR3757 MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPG
************************************************************
COL MNGIEITEYIKAHYPDIKVLVLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVM
N315 MNGIEITEYIKAHYPEIKVLVLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVM
NCTC8325 MNGIEITEYIKAHYPDIKVLVLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVM
Newman MNGIEITEYIKAHYPDIKVLVLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVM
USA300_FPR3757 MNGIEITEYIKAHYPDIKVLVLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVM
***************:********************************************
COL NGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVKGKTNKEIAETLFVSEKTIKT
N315 NGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVKGKTNKEIAETLFVSEKTIKT
NCTC8325 NGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVKGKTNKEIAETLFVSEKTIKT
Newman NGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVKGKTNKEIAETLFVSEKTIKT
USA300_FPR3757 NGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVKGKTNKEIAETLFVSEKTIKT
************************************************************
COL HVSHIFSKLQVSDRTQAAIYAMENKLI
N315 HVSHIFSKLQVSDRTQAAIYAMENKLI
NCTC8325 HVSHIFSKLQVSDRTQAAIYAMENKLI
Newman HVSHIFSKLQVSDRTQAAIYAMENKLI
USA300_FPR3757 HVSHIFSKLQVSDRTQAAIYAMENKLI
***************************
- ↑ Lisa Bleul, Patrice Francois, Christiane Wolz
Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms.
Genes (Basel): 2021, 13(1);
[PubMed:35052374] [WorldCat.org] [DOI] (I e)Fei Sun, Quanjiang Ji, Marcus B Jones, Xin Deng, Haihua Liang, Bryan Frank, Joshua Telser, Scott N Peterson, Taeok Bae, Chuan He
AirSR, a [2Fe-2S] cluster-containing two-component system, mediates global oxygen sensing and redox signaling in Staphylococcus aureus.
J Am Chem Soc: 2012, 134(1);305-14
[PubMed:22122613] [WorldCat.org] [DOI] (I p)Haipeng Sun, Yifan Yang, Ting Xue, Baolin Sun
Modulation of cell wall synthesis and susceptibility to vancomycin by the two-component system AirSR in Staphylococcus aureus NCTC8325.
BMC Microbiol: 2013, 13;286
[PubMed:24320748] [WorldCat.org] [DOI] (I e)Jeffrey W Hall, Junshu Yang, Haiyong Guo, Yinduo Ji
The AirSR two-component system contributes to Staphylococcus aureus survival in human blood and transcriptionally regulates sspABC operon.
Front Microbiol: 2015, 6;682
[PubMed:26191060] [WorldCat.org] [DOI] (P e)Jeffrey W Hall, Junshu Yang, Haiyong Guo, Yinduo Ji
The Staphylococcus aureus AirSR Two-Component System Mediates Reactive Oxygen Species Resistance via Transcriptional Regulation of Staphyloxanthin Production.
Infect Immun: 2017, 85(2);
[PubMed:27872240] [WorldCat.org] [DOI] (I e) - ↑ Jeffrey W Hall, Junshu Yang, Haiyong Guo, Yinduo Ji
The Staphylococcus aureus AirSR Two-Component System Mediates Reactive Oxygen Species Resistance via Transcriptional Regulation of Staphyloxanthin Production.
Infect Immun: 2017, 85(2);
[PubMed:27872240] [WorldCat.org] [DOI] (I e)