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⊟Summary[edit | edit source]
- pan ID?: SAUPAN004921000
- symbol?: rumA
- synonym:
- description?: RNA methyltransferase
- RNA methyltransferase
- 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
- RNA methyltransferase TrmA family protein
- 23S rRNA (uracil-5-)-methyltransferase RumA
- 23S rRNA m(5)U1939 methyltransferase
- putative RNA methyltransferase
- RNA methyltransferase, TrmA family
- RNA methyltransferase-like protein
- rRNA methyltransferase RumA
- TrmA family RNA methyltransferase
- Uncharacterized RNA methyltransferase
descriptions from strain specific annotations:
- strand?: -
- coordinates?: 5109944..5111305
- synteny block?: BlockID0038270
- occurrence?: in 100% of 33 strains
rumA (rlmCD): 23S rRNA uridine(792),cytidine(1966)-(5)-methyltransferase [1]
⊟Orthologs[edit | edit source]
04-02981:
SA2981_1853
08BA02176:
C248_1971
11819-97:
MS7_1932 (rumA)
6850:
RSAU_001784
71193:
ST398NM01_1990
ECT-R 2:
ECTR2_1768 (rumA)
ED133:
SAOV_1996
ED98:
SAAV_1963 (rumA)
HO 5096 0412:
SAEMRSA15_18040
JH1:
SaurJH1_1985
JH9:
SaurJH9_1951
JKD6008:
SAA6008_01917
JKD6159:
SAA6159_01828
LGA251:
SARLGA251_17790
M013:
M013TW_1933
MRSA252:
SAR1988
MSHR1132:
SAMSHR1132_17420
MSSA476:
SAS1819
Mu3:
SAHV_1882
Mu50:
SAV1897
MW2:
MW1838
RF122:
SAB1829c
ST398:
SAPIG1990 (rumA)
T0131:
SAT0131_02022 (gap)
TCH60:
HMPREF0772_11246 (rumA)
TW20:
SATW20_18910
USA300_TCH1516:
USA300HOU_1896
VC40:
SAVC_08745
⊟Genome Viewer[edit | edit source]
| COL | |
| N315 | |
| NCTC8325 | |
| Newman | |
| USA300_FPR3757 |
⊟Alignments[edit | edit source]
- alignment of orthologues: CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
COL MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLL
N315 MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLL
NCTC8325 MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLL
Newman MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLL
USA300_FPR3757 MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLL
************************************************************
COL NINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTV
N315 NINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTV
NCTC8325 NINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTV
Newman NINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTV
USA300_FPR3757 NINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTV
************************************************************
COL GMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSIL
N315 GMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSIL
NCTC8325 GMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSIL
Newman GMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSIL
USA300_FPR3757 GMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSIL
************************************************************
COL KDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
N315 KDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
NCTC8325 KDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
Newman KDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
USA300_FPR3757 KDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
************************************************************
COL SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAI
N315 SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAI
NCTC8325 SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAI
Newman SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAI
USA300_FPR3757 SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAI
************************************************************
COL EYAQLTGNEVVLDTYCGIGTIGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFV
N315 EYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSSIEDAQQNATINQCNNTTFV
NCTC8325 EYAQLTGNEVVLDTYCGIGTIGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFV
Newman EYAQLTGNEVVLDTYCGIGTIGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFV
USA300_FPR3757 EYAQLTGNEVVLDTYCGIGTIGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFV
*************************** ************:*******************
COL CGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDA
N315 CGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDA
NCTC8325 CGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDA
Newman CGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDA
USA300_FPR3757 CGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDA
************************************************************
COL LLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
N315 LLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
NCTC8325 LLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
Newman LLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
USA300_FPR3757 LLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
*********************************
- ↑ Adrián González-López, Daniel S D Larsson, Ravi Kiran Koripella, Brett N Cain, Martin Garcia Chavez, Paul J Hergenrother, Suparna Sanyal, Maria Selmer
Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.
Sci Rep: 2024, 14(1);14253
[PubMed:38902339] [WorldCat.org] [DOI] (I e)