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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

Summary[edit | edit source]

  • pan ID?: SAUPAN005050000
  • symbol?:
  • synonym:
  • description?: phi77 ORF100-like protein

      descriptions from strain specific annotations:

    • phi77 ORF100-like protein
    • putative bacteriophage protein
    • phage protein
    • Phi77 hypothetical protein
    • phi77 protein
  • strand?: -
  • coordinates?: 5218159..5218439
  • synteny block?: BlockID0039280
  • occurrence?: in 41% of 34 strains

tacL (gpGT) : serogroup F prophage tail assembly chaperone large subunit [1]

Staphylococcal prophages require tail assembly chaperone proteins (TACs) to coat the tape measure protein and prevent asynchronized and unstructured major tail tube protein binding. They will then nucleate major tail tube protein polymerization and be displaced by major tail tube protein subunits in orderly tail tube assembly. This large subunit actually originates from SAUPAN005052000 and is generated via a 1% frequency programmed translational frameshift at the A AAT TTT slippery coding sequence. This results in ribosomal slippage to the +3 reading frame and a 179 amino acid protein.

Orthologs[edit | edit source]

    COL:
    N315:
    NCTC8325:
    Newman:
    USA300_FPR3757:
    04-02981:
    08BA02176:
    11819-97:
    6850:
    RSAU_000607
    71193:
    ST398NM01_2920
    ECT-R 2:
    ECTR2_1828
    ED133:
    ED98:
    HO 5096 0412:
    SAEMRSA15_18710
    JH1:
    SaurJH1_2047
    JH9:
    SaurJH9_2011
    JKD6008:
    SAA6008_02010
    JKD6159:
    JSNZ:
    LGA251:
    M013:
    MRSA252:
    SAR2051
    MSHR1132:
    SAMSHR1132_17960
    MSSA476:
    Mu3:
    Mu50:
    MW2:
    RF122:
    ST398:
    T0131:
    SAT0131_02089
    TCH60:
    HMPREF0772_11185
    TW20:
    SATW20_19480
    USA300_TCH1516:
    USA300HOU_1960
    VC40:

Genome Viewer[edit | edit source]

Alignments[edit | edit source]

  • alignment of orthologues:

  1. Jun Xu, Roger W Hendrix, Robert L Duda
    Conserved translational frameshift in dsDNA bacteriophage tail assembly genes.
    Mol Cell: 2004, 16(1);11-21
    [PubMed:15469818] [WorldCat.org] [DOI] (P p)
    Lisa G Pell, Nichole Cumby, Teresa E Clark, Ashleigh Tuite, Kevin P Battaile, Aled M Edwards, Nickolay Y Chirgadze, Alan R Davidson, Karen L Maxwell
    A conserved spiral structure for highly diverged phage tail assembly chaperones.
    J Mol Biol: 2013, 425(14);2436-49
    [PubMed:23542344] [WorldCat.org] [DOI] (I p)