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PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

Summary[edit | edit source]

  • pan ID?: SAUPAN005054000
  • symbol?:
  • synonym:
  • description?: Bacterial Ig-like domain-containing protein

      descriptions from strain specific annotations:

    • Bacterial Ig-like domain-containing protein
    • initmin-like phage surface protein
    • Phage protein
  • strand?: -
  • coordinates?: 5219932..5221073
  • synteny block?: BlockID0039300
  • occurrence?: in 29% of 34 strains

mtpL : serogroup F prophage major tail tube protein large subunit [1]

Most staphylococcal prophages require two major tail tube proteins to form orderly coiled polymers around the tail tape measure protein. While some prophage encode the two tail tube proteins as separate genes, Serogroup F prophage generates its longer "MtpL" variant via a programmed translational frameshift analogous to the mechanism used to generate structural diversity in tail assembly chaperones. As such, this mtpL coding sequence actually originates from SAUPAN005055000 and is generated via a 25% frequency programmed translational frameshift at the T TTG TAA slippery coding sequence. This results in ribosomal slippage to the +3 reading frame and a 303 amino acid protein ending in the stop codon from SAUPAN005054000.

Orthologs[edit | edit source]

    COL:
    N315:
    NCTC8325:
    Newman:
    USA300_FPR3757:
    JSNZ:
    04-02981:
    SA2981_1918
    08BA02176:
    11819-97:
    6850:
    71193:
    ST398NM01_2922
    ECT-R 2:
    ECTR2_1830
    ED133:
    ED98:
    HO 5096 0412:
    JH1:
    SaurJH1_2049
    JH9:
    SaurJH9_2013
    JKD6008:
    SAA6008_02012
    JKD6159:
    LGA251:
    M013:
    MRSA252:
    SAR2053
    MSHR1132:
    MSSA476:
    Mu3:
    Mu50:
    MW2:
    RF122:
    ST398:
    T0131:
    SAT0131_02091
    TCH60:
    HMPREF0772_11183
    TW20:
    USA300_TCH1516:
    VC40:

Genome Viewer[edit | edit source]

Alignments[edit | edit source]

  • alignment of orthologues:

  1. Jun Xu, Roger W Hendrix, Robert L Duda
    Conserved translational frameshift in dsDNA bacteriophage tail assembly genes.
    Mol Cell: 2004, 16(1);11-21
    [PubMed:15469818] [WorldCat.org] [DOI] (P p)
    Isabelle Auzat, Anja Dröge, Frank Weise, Rudi Lurz, Paulo Tavares
    Origin and function of the two major tail proteins of bacteriophage SPP1.
    Mol Microbiol: 2008, 70(3);557-69
    [PubMed:18786146] [WorldCat.org] [DOI] (I p)