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Summary[edit | edit source]

  • pan ID?: SAUPAN006269000
  • symbol?: pyrD
  • synonym:
  • description?: dihydroorotate dehydrogenase 2

      descriptions from strain specific annotations:

    • dihydroorotate dehydrogenase 2
    • dihydroorotate dehydrogenase (quinone)
    • dihydroorotate dehydrogenase
    • quinone-dependent dihydroorotate dehydrogenase
    • dihydroorotate oxidase
    • putative dihydroorotate dehydrogenase
  • strand?: +
  • coordinates?: 6320594..6321658
  • synteny block?: BlockID0049920
  • occurrence?: in 100% of 33 strains

pyrD : dihydroorotate:quinone oxidoreductase [1]

Orthologs[edit | edit source]

    COL:
    SACOL2606 (pyrD)
    N315:
    NCTC8325:
    Newman:
    NWMN_2488 (pyrD)
    USA300_FPR3757:
    04-02981:
    SA2981_2527
    08BA02176:
    C248_2650
    11819-97:
    MS7_2595 (pyrD)
    6850:
    RSAU_002430 (pyrD)
    71193:
    ST398NM01_2639
    ECT-R 2:
    ECTR2_2443 (pyrD)
    ED133:
    SAOV_2634
    ED98:
    SAAV_2655 (pyrD)
    HO 5096 0412:
    SAEMRSA15_24920
    JH1:
    SaurJH1_2665
    JH9:
    SaurJH9_2611
    JKD6008:
    SAA6008_02648 (pyrD)
    JKD6159:
    SAA6159_02486 (pyrD)
    LGA251:
    SARLGA251_23630
    M013:
    M013TW_2563
    MRSA252:
    SAR2669
    MSHR1132:
    SAMSHR1132_24040
    MSSA476:
    SAS2475
    Mu3:
    SAHV_2573
    Mu50:
    SAV2589
    MW2:
    MW2509
    RF122:
    SAB2464
    ST398:
    SAPIG2639 (pyrD)
    T0131:
    SAT0131_02823 (hisB)
    TCH60:
    HMPREF0772_10602 (pyrD)
    TW20:
    SATW20_27300
    USA300_TCH1516:
    USA300HOU_2583 (pyrD)
    VC40:
    SAVC_11825

Genome Viewer[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

Alignments[edit | edit source]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.307)


    COL             MYKLIKPFLFKIEPEKAHGLTIDALKTLQKFPVLFPVVDKLFTYKNPTLSQTIQGNTYDN
    N315            MYKLIKPFLFKIEPEKAHGLTIDALKTLQKFPVLFPVVDKLFTYKNPTLSQTIQGNTYDN
    NCTC8325        MYKLIKPFLFKIEPEKAHGLTIDALKTLQKFPVLFPVVDKLFTYKNPTLSQTIQGNTYDN
    Newman          MYKLIKPFLFKIEPEKAHGLTIDALKTLQKFPVLFPVVDKLFTYKNPTLSQTIQGNTYDN
    USA300_FPR3757  MYKLIKPFLFKIEPEKAHGLTIDALKTLQKFPVLFPVVDKLFTYKNPTLSQTIQGNTYDN
                    ************************************************************

    COL             PIGLAAGFDKSCEVPKALEHLGFGALELGGITPKPQPGNPQPRMFRLLEDDALINRMGFN
    N315            PIGLAAGFDKSCEVPKALEHLGFGALELGGITPKPQPGNPQPRMFRLLEDDALINRMGFN
    NCTC8325        PIGLAAGFDKSCEVPKALEHLGFGALELGGITPKPQPGNPQPRMFRLLEDDALINRMGFN
    Newman          PIGLAAGFDKSCEVPKALEHLGFGALELGGITPKPQPGNPQPRMFRLLEDDALINRMGFN
    USA300_FPR3757  PIGLAAGFDKSCEVPKALEHLGFGALELGGITPKPQPGNPQPRMFRLLEDDALINRMGFN
                    ************************************************************

    COL             NIGMNKALSHLRKNAYQVPVGINVGVNKMTPYEARYQDYIKVIDTFKHDVSFFTVNISSP
    N315            NIGMNKALSHLRKNAYQVPVGINVGVNKMTPYEARYQDYIKVIDTFKHDVSFFTVNISSP
    NCTC8325        NIGMNKALSHLRKNAYQVPVGINVGVNKMTPYEARYQDYIKVIDTFKHDVSFFTVNISSP
    Newman          NIGMNKALSHLRKNAYQVPVGINVGVNKMTPYEARYQDYIKVIDTFKHDVSFFTVNISSP
    USA300_FPR3757  NIGMNKALSHLRKNAYQVPVGINVGVNKMTPYEARYQDYIKVIDTFKHDVSFFTVNISSP
                    ************************************************************

    COL             NTENLQNFHDKDEFSMLCQALTAFKKQHDVTVPIYLKLTSDMDFDGLKALLPAITETFDG
    N315            NTENLQNFHDKDEFSMLCQALTTFKKQHDVTVPIYLKLTSDMDFDGLKALLPAITETFDG
    NCTC8325        NTENLQNFHDKDEFSMLCQALTAFKKQHDVTVPIYLKLTSDMDFDGLKALLPAITETFDG
    Newman          NTENLQNFHDKDEFSMLCQALTAFKKQHDVTVPIYLKLTSDMDFDGLKALLPAITETFDG
    USA300_FPR3757  NTENLQNFHDKDEFSMLCQALTAFKKQHDVTVPIYLKLTSDMDFDGLKALLPAITETFDG
                    **********************:*************************************

    COL             IILANTTRQRDGLTSANKVEEGGLSGRPLFERNLKLIKYAYQQTNGEFLIIGTGGVFSTE
    N315            IILANTTRQRDGLTSANKVEEGGLSGRPLFERNLKLIKYAYQQTNGEFLIIGTGGVFSTE
    NCTC8325        IILANTTRQRDGLTSANKVEEGGLSGRPLFERNLKLIKYAYQQTNGEFLIIGTGGVFSTE
    Newman          IILANTTRQRDGLTSANKVEEGGLSGRPLFERNLKLIKYAYQQTNGEFLIIGTGGVFSTE
    USA300_FPR3757  IILANTTRQRDGLTSANKVEEGGLSGRPLFERNLKLIKYAYQQTNGEFLIIGTGGVFSTE
                    ************************************************************

    COL             DAIKMMRHGASLIQIYSSLVIEGPGLTKKMNKGIARYLKDHHFDNVSDIIGLDA
    N315            DAIKMMRHGASLIQIYSSLVIEGPGLTKKMNKGIARYLKDHHFDNVSDIIGLDA
    NCTC8325        DAIKMMRHGASLIQIYSSLVIEGPGLTKKMNKGIARYLKDHHFDNVSDIIGLDA
    Newman          DAIKMMRHGASLIQIYSSLVIEGPGLTKKMNKGIARYLKDHHFDNVSDIIGLDA
    USA300_FPR3757  DAIKMMRHGASLIQIYSSLVIEGPGLTKKMNKGIARYLKDHHFDNVSDIIGLDA
                    ******************************************************

  1. Filipe M Sousa, Patrícia Pires, Andreia Barreto, Patrícia N Refojo, Micael S Silva, Pedro B Fernandes, Ana P Carapeto, Tiago T Robalo, Mário S Rodrigues, Mariana G Pinho, Eurico J Cabrita, Manuela M Pereira
    Unveiling the membrane bound dihydroorotate: Quinone oxidoreductase from Staphylococcus aureus.
    Biochim Biophys Acta Bioenerg: 2023, 1864(2);148948
    [PubMed:36481274] [WorldCat.org] [DOI] (I p)