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Summary[edit | edit source]

  • pan ID?: SAUPAN006309000
  • symbol?: mbcS
  • synonym:
  • description?: acetyl-CoA synthetase

      descriptions from strain specific annotations:

    • acetyl-CoA synthetase
    • acetate-CoA ligase
    • acetate-CoA ligase, AMP-dependent
    • acyl--CoA ligase
    • putative AMP-binding enzyme
    • acetyl-CoA synthetase, putative
    • acetyl-coenzyme A synthetase
    • Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase
    • acyl-coenzyme A synthetase/AMP-(fatty) acidligases, YtcI-like protein
    • AMP-binding protein
    • AMP-dependent synthetase and ligase
  • strand?: -
  • coordinates?: 6353573..6355171
  • synteny block?: BlockID0050250
  • occurrence?: in 100% of 33 strains

Orthologs[edit | edit source]

    COL:
    N315:
    NCTC8325:
    Newman:
    USA300_FPR3757:
    04-02981:
    SA2981_2547
    08BA02176:
    C248_2667
    11819-97:
    MS7_2613
    6850:
    RSAU_002449
    71193:
    ST398NM01_2656
    ECT-R 2:
    ECTR2_2462
    ED133:
    SAOV_2653c
    ED98:
    SAAV_2675
    HO 5096 0412:
    SAEMRSA15_25130
    JH1:
    SaurJH1_2685
    JH9:
    SaurJH9_2631
    JKD6008:
    SAA6008_02666 (acsA2)
    JKD6159:
    SAA6159_02505 (acsA2)
    LGA251:
    SARLGA251_23810
    M013:
    M013TW_2586
    MRSA252:
    SAR2687
    MSHR1132:
    SAMSHR1132_24240
    MSSA476:
    SAS2494
    Mu3:
    SAHV_2593
    Mu50:
    SAV2609
    MW2:
    MW2528
    RF122:
    SAB2482c
    ST398:
    SAPIG2656
    T0131:
    SAT0131_02842
    TCH60:
    HMPREF0772_10583 (acsA)
    TW20:
    SATW20_27470
    USA300_TCH1516:
    USA300HOU_2602 (acsA2)
    VC40:
    SAVC_11905

Genome Viewer[edit | edit source]

COL
N315
NCTC8325
Newman
USA300_FPR3757

Alignments[edit | edit source]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.307)


    COL             -------MQKSALFAPEKYNIISEIEKYSHIPDKKAILYHNTEGEDISVTYQQLIEQSNK
    N315            MYERKLVMQKSALFAPEKYNIISEIEKYSHIPDKKAILYHNTEGEDISVTYQQLIEQSNK
    NCTC8325        -------MQKSALFAPEKYNIISEIEKYSHIPDKKAILYHNTEGEDISVTYQQLIEQSNK
    Newman          MYERKLVMQKSALFAPEKYNIISEIEKYSHIPDKKAILYHNTEGEDISVTYQQLIEQSNK
    USA300_FPR3757  -------MQKSALFAPEKYNIISEIEKYSHIPDKKAILYHNTEGEDISVTYQQLIEQSNK
                           *****************************************************

    COL             VGNVLASHGLSKGDKVLIMMPRSIATYELYIAALKLGVAIIPCSEMLRTKDLQYRITHGE
    N315            VGNVLASHGLSKGDKVLIMMPRSIATYELYIAALKLGVAIIPCSEMLRTKDLQYRITHGE
    NCTC8325        VGNVLASHGLSKGDKVLIMMPRSIATYELYIAALKLGVAIIPCSEMLRTKDLQYRITHGE
    Newman          VGNVLASHGLSKGDKVLIMMPRSIATYELYIAALKLGVAIIPCSEMLRTKDLQYRITHGE
    USA300_FPR3757  VGNVLASHGLSKGDKVLIMMPRSIATYELYIAALKLGVAIIPCSEMLRTKDLQYRITHGE
                    ************************************************************

    COL             INAVIALEPFTVEFEKIKEYDALTKFVIAGQKDGWISLEAEKENASNKLEMADTTRDDMA
    N315            INAVIALEPFTVEFEKIKEYDALTKFVIAGQKDGWISLEAEKENASNKLEMADTTRDDMA
    NCTC8325        INAVIALEPFTVEFEKIKEYDALTKFVIAGQKDGWISLEAEKENASNKLEMADTTRDDMA
    Newman          INAVIALEPFTVEFEKIKEYDALTKFVIAGQKDGWISLEAEKENASNKLEMADTTRDDMA
    USA300_FPR3757  INAVIALEPFTVEFEKIKEYDALTKFVIAGQKDGWISLEAEKENASNKLEMADTTRDDMA
                    ************************************************************

    COL             ILSYTSGTTGNPKAVTHCHGWGFAHLQMAPKHWLCINEDDLVWATAAPGWQKWVWSPFLS
    N315            ILSYTSGTTGNPKAVTHCHGWGFAHLQMAPKHWLCINEDDLVWATAAPGWQKWVWSPFLS
    NCTC8325        ILSYTSGTTGNPKAVTHCHGWGFAHLQMAPKHWLCINEDDLVWATAAPGWQKWVWSPFLS
    Newman          ILSYTSGTTGNPKAVTHCHGWGFAHLQMAPKHWLCINEDDLVWATAAPGWQKWVWSPFLS
    USA300_FPR3757  ILSYTSGTTGNPKAVTHCHGWGFAHLQMAPKHWLCINEDDLVWATAAPGWQKWVWSPFLS
                    ************************************************************

    COL             VLGSGATAFVFNGRFSPETYLELLQKYQINVLCCTPTEYRMMAKLQNLNDYDLTHLHSAV
    N315            VLGSGATAFVFNGRFSPETYLELLQKYQINVLCCTPTEYRMMAKLQNLNDYDLTHLHSAV
    NCTC8325        VLGSGATAFVFNGRFSPETYLELLQKYQINVLCCTPTEYRMMAKLQNLNDYDLTHLHSAV
    Newman          VLGSGATAFVFNGRFSPETYLELLQKYQINVLCCTPTEYRMMAKLQNLNDYDLTHLHSAV
    USA300_FPR3757  VLGSGATAFVFNGRFSPETYLELLQKYQINVLCCTPTEYRMMAKLQNLNDYDLTHLHSAV
                    ************************************************************

    COL             SAGEPLNREVVEQFKKYFNLTVRDGYGQTESTLLIGFLKDTPQRIGSMGKGIPGSSVTVV
    N315            SAGEPLNREVVEQFKKYFNLTVRDGYGQTESTLLIGFLKDTPQRIGSMGKGIPGSSVTVV
    NCTC8325        SAGEPLNREVVEQFKKYFNLTVRDGYGQTESTLLIGFLKDTPQRIGSMGKGIPGSSVTVV
    Newman          SAGEPLNREVVEQFKKYFNLTVRDGYGQTESTLLIGFLKDTPQRIGSMGKGIPGSSVTVV
    USA300_FPR3757  SAGEPLNREVVEQFKKYFNLTVRDGYGQTESTLLIGFLKDTPQRIGSMGKGIPGSSVTVV
                    ************************************************************

    COL             DDEGNSVPANTKGNIAVPLDLPALFKGYYKEPERTAKAQTGKYYITGDLAHVDDDGYFWF
    N315            DDEGNSVPANTKGNIAVPLDLPALFKGYYKEPERTAKAQTGKYYITGDLAHVDDDGYFWF
    NCTC8325        DDEGNSVPANTKGNIAVPLDLPALFKGYYKEPERTAKAQTGKYYITGDLAHVDDDGYFWF
    Newman          DDEGNSVPANTKGNIAVPLDLPALFKGYYKEPERTAKAQTGKYYITGDLAHVDDDGYFWF
    USA300_FPR3757  DDEGNSVPANTKGNIAVPLDLPALFKGYYKEPERTAKAQTGKYYITGDLAHVDDDGYFWF
                    ************************************************************

    COL             EGRRDDIIISSGYTIGPFEVEDALTNHPAVKECAVVAKPHDIRGNIVKAFVILQDHTAGD
    N315            EGRRDDIIISSGYTIGPFEVEDALTNHPAVKECAVVAKPHDIRGNIVKAFVILQDHTAGD
    NCTC8325        EGRRDDIIISSGYTIGPFEVEDALTNHPAVKECAVVAKPHDIRGNIVKAFVILQDHTAGD
    Newman          EGRRDDIIISSGYTIGPFEVEDALTNHPAVKECAVVAKPHDIRGNIVKAFVILQDHTAGD
    USA300_FPR3757  EGRRDDIIISSGYTIGPFEVEDALTNHPAVKECAVVAKPHDIRGNIVKAFVILQDHTAGD
                    ************************************************************

    COL             DTLVKELQQFVKNEVAPYKYPREIEFVDDLPKTNSGKIRRVELRDAEIEKWQQQKDSNQ
    N315            DTLVKELQQFVKNEVAPYKYPREIEFVDDLPKTNSGKIRRVELRDSEIEKWQQQKDSNQ
    NCTC8325        DTLVKELQQFVKNEVAPYKYPREIEFVDDLPKTNSGKIRRVELRDAEIEKWQQQKDSNQ
    Newman          DTLVKELQQFVKNEVAPYKYPREIEFVDDLPKTNSGKIRRVELRDAEIEKWQQQKDSNQ
    USA300_FPR3757  DTLVKELQQFVKNEVAPYKYPREIEFVDDLPKTNSGKIRRVELRDAEIEKWQQQKDSNQ
                    *********************************************:*************