From AureoWiki
Jump to navigation Jump to search

NCBI: 10-JUN-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_1197 [new locus tag: SAUSA300_RS06465 ]
  • pan locus tag?: SAUPAN003622000
  • symbol: SAUSA300_1197
  • pan gene symbol?: bsaA
  • synonym:
  • product: glutathione peroxidase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_1197 [new locus tag: SAUSA300_RS06465 ]
  • symbol: SAUSA300_1197
  • product: glutathione peroxidase
  • replicon: chromosome
  • strand: -
  • coordinates: 1319065..1319541
  • length: 477
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGAGACAATTTATGATTTTGTAGTAGAAACAAATAAAGGTGTTACTTACAAATTAGAT
    GCATATAAGGGTGACGTTATGCTAATTGTTAATACAGCTAGCGAATGTGGCTTTACTTCA
    CAATTTGAAGGTTTGCAATCATTATACGAGAAATACAAAGATCAAGGGTTTGTAATTCTA
    GGTTTCCCTTGTAATCAATTTGGTGGCCAAGAACCTGGTTCAGGCGAAGAAGCAGCTCAA
    AACTGTAAATTAAACTATGGTGTTACCTTCCCTATGCATCAAAAAATAGACGTAAAAGGG
    GAACATCAATTACCTTTATTTAGATATTTGACTGCGGCACAACACGGATTCTTTAATGAG
    AAAATCAAATGGAATTTCACTAAGTTTTTAGTGGATCGCGAAGGTAACGTTGTTAAACGA
    TTTGCACCTCAAAAAAAACCTGTTCAAATCGAAAGAGAAATAGAAAAATTATTATAA
    60
    120
    180
    240
    300
    360
    420
    477

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_1197 [new locus tag: SAUSA300_RS06465 ]
  • symbol: SAUSA300_1197
  • description: glutathione peroxidase
  • length: 158
  • theoretical pI: 6.77696
  • theoretical MW: 18117.6
  • GRAVY: -0.423418

Function[edit | edit source]

  • TIGRFAM:
    putative glutathione peroxidase Gpx7 (TIGR02540; EC 1.11.1.9; HMM-score: 131.3)
  • TheSEED  :
    • Glutathione peroxidase (EC 1.11.1.9)
    • Thioredoxin peroxidase (EC 1.11.1.24)
    Stress Response Oxidative stress Glutathione: Redox cycle  Glutathione peroxidase (EC 1.11.1.9)
    and 1 more
    Stress Response Oxidative stress Glutathione: Redox cycle  Glutathione peroxidase family protein
  • PFAM:
    Thioredoxin (CL0172) GSHPx; Glutathione peroxidase (PF00255; HMM-score: 131.5)
    and 2 more
    AhpC-TSA; AhpC/TSA family (PF00578; HMM-score: 25.7)
    Redoxin; Redoxin (PF08534; HMM-score: 19.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.047312
    • TAT(Tat/SPI): 0.000368
    • LIPO(Sec/SPII): 0.004337
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • METIYDFVVETNKGVTYKLDAYKGDVMLIVNTASECGFTSQFEGLQSLYEKYKDQGFVILGFPCNQFGGQEPGSGEEAAQNCKLNYGVTFPMHQKIDVKGEHQLPLFRYLTAAQHGFFNEKIKWNFTKFLVDREGNVVKRFAPQKKPVQIEREIEKLL

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]