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NCBI: 10-JUN-2013

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_2285 [new locus tag: SAUSA300_RS12630 ]
  • pan locus tag?: SAUPAN005829000
  • symbol: galM
  • pan gene symbol?: galM
  • synonym:
  • product: aldose 1-epimerase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_2285 [new locus tag: SAUSA300_RS12630 ]
  • symbol: galM
  • product: aldose 1-epimerase
  • replicon: chromosome
  • strand: -
  • coordinates: 2457407..2458426
  • length: 1020
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGATAGTTGAAGTTGAGCACCAAAGACAAGGTGTAGATTTAATCAAAATTGATAATGAT
    GAAACTAAAATTATTTTTACGAATTATGGAGCAAGAGTAGTGTCTTGGAAATATCATGAT
    AATAATATTGTTCTTGGAAATGTTGTTGAAGCGGATGAATTTTATCATAGTAATCCTTTT
    AAATTTGGTGCTTCTATAGGAAGATATAGCGGTAGAATTGATAATGCTAAATTTAAGTTG
    AAAGGTAAAGAATATCAGTTAGAAAAAAACAACGGTGAACATCATTTACATGGTGGATGT
    CATGGTTTGGACAATAAGTTATTTGATTATGAAATTAGAAATGAAATTGCTCAAATTAAA
    GTTATATTTAAGACGGTGTTGAAATCAGCTGATGATCATTTCCCGGGTGATATCGATGTG
    ACGATTACACATATTTATGATGCGGATCACCAATGGTCGATTGAATACGAAGCAGTTGCA
    TCAGAAGACACATTGTTTAGTCCTACGAATCATGTGTACTTCAATTTGAATCGAGATAAT
    AATGTCGTTGATAATCATCGCATTTCAAGTAATCAATTAGATATGTATGTATTAGATGAG
    CGAAATATTGTTACAGGTGATATTCTAGATTTACATGAAGTGTTTGAAGATAACAAGATA
    AAATTGAGTGATATTTTTACATCACAACATGCGCAATTAAGCCAACAAATGACACGTTTT
    GGTGGTCTCGATCACCCATTTACAGTTGGTGAACATAAAATGTATGTTGAAAATCATGAA
    TTTATGTTAGAGGTCGATACAGATATGCCTCATGTTGTGTTCTTTACTTTTAACCAGCCT
    GATGAGTGGGATAGTCCATTTAATATTTATAAACCACATTCTGGCTTTACATTAGAAACA
    CAATTTTTACCAAATGATATTAATTTATATGGTGAAAAAGCACCGTCAATTTTAAAAGCT
    GGTGAAGTGTTCAATTCGAAAACAAGTTTCCGTATCGAAGAAAAAGTAGAAAATGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_2285 [new locus tag: SAUSA300_RS12630 ]
  • symbol: GalM
  • description: aldose 1-epimerase
  • length: 339
  • theoretical pI: 4.83314
  • theoretical MW: 39279.3
  • GRAVY: -0.564897

⊟Function[edit | edit source]

  • reaction:
    EC 5.1.3.3?  ExPASy
    Aldose 1-epimerase Alpha-D-glucose = beta-D-glucose
  • TIGRFAM:
    galactose mutarotase (TIGR02636; EC 5.1.3.3; HMM-score: 202)
  • TheSEED  :
    • Aldose 1-epimerase (EC 5.1.3.3)
    Carbohydrates Di- and oligosaccharides Lactose and Galactose Uptake and Utilization  Aldose 1-epimerase (EC 5.1.3.3)
    and 1 more
    Carbohydrates Di- and oligosaccharides Maltose and Maltodextrin Utilization  Aldose 1-epimerase (EC 5.1.3.3)
  • PFAM:
    Gal_mutarotase (CL0103) Aldose_epim; Aldose 1-epimerase (PF01263; HMM-score: 200.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005433
    • TAT(Tat/SPI): 0.000198
    • LIPO(Sec/SPII): 0.00079
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIVEVEHQRQGVDLIKIDNDETKIIFTNYGARVVSWKYHDNNIVLGNVVEADEFYHSNPFKFGASIGRYSGRIDNAKFKLKGKEYQLEKNNGEHHLHGGCHGLDNKLFDYEIRNEIAQIKVIFKTVLKSADDHFPGDIDVTITHIYDADHQWSIEYEAVASEDTLFSPTNHVYFNLNRDNNVVDNHRISSNQLDMYVLDERNIVTGDILDLHEVFEDNKIKLSDIFTSQHAQLSQQMTRFGGLDHPFTVGEHKMYVENHEFMLEVDTDMPHVVFFTFNQPDEWDSPFNIYKPHSGFTLETQFLPNDINLYGEKAPSILKAGEVFNSKTSFRIEEKVEND

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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