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NCBI: 10-JUN-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_2626 [new locus tag: SAUSA300_RS14590 ]
  • pan locus tag?: SAUPAN006450000
  • symbol: SAUSA300_2626
  • pan gene symbol?: bstA
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_2626 [new locus tag: SAUSA300_RS14590 ]
  • symbol: SAUSA300_2626
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2852036..2852500
  • length: 465
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGACTACAAAAACAGTATTTGATGTCATTGATATGGGGTTAGGATATTTAGTAAATGTG
    TATGATGCTTGGAAAGTTGAAAAGGTACTTGATGATTATCATAAGCCTTTTTCTAATACC
    ATTCATTGGCAATTTGGTCATGTATTAACAATTTTTGAATCGGCCTTAGCTGTTGCTGGT
    AAAGAGAATATTGATTTAAATATCTATAGACCTTTATTCGGAAATGGTTCGTCTCCAGAT
    GAATGGAAGGATGAAGTACCGAGTATTGAAAGGATTTTAGAAGGTCTCCAAACTTTACCT
    GAACGTGCACGAAATCTAACTGAAGATGATTTAGCAATTGAATTGAAACAGCCAATTGTC
    GGTTGTAATAACTTAGAAGAGTTATTAGTATTAAATGCCATTCACATCCCACTTCATGCT
    GGTAAAATTGAAGAGATGTCTCGTATATTAAAAAATTTAAAATAA
    60
    120
    180
    240
    300
    360
    420
    465

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_2626 [new locus tag: SAUSA300_RS14590 ]
  • symbol: SAUSA300_2626
  • description: hypothetical protein
  • length: 154
  • theoretical pI: 4.72146
  • theoretical MW: 17511
  • GRAVY: -0.143506

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • FIG01107962: hypothetical protein
  • PFAM:
    DinB (CL0310) DinB_2; DinB superfamily (PF12867; HMM-score: 22.2)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00392
    • TAT(Tat/SPI): 0.000197
    • LIPO(Sec/SPII): 0.000499
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MTTKTVFDVIDMGLGYLVNVYDAWKVEKVLDDYHKPFSNTIHWQFGHVLTIFESALAVAGKENIDLNIYRPLFGNGSSPDEWKDEVPSIERILEGLQTLPERARNLTEDDLAIELKQPIVGCNNLEELLVLNAIHIPLHAGKIEEMSRILKNLK

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]

Varahenage R Perera, Gerald L Newton, Kit Pogliano
Bacillithiol: a key protective thiol in Staphylococcus aureus.
Expert Rev Anti Infect Ther: 2015, 13(9);1089-107
[PubMed:26184907] [WorldCat.org] [DOI] (I p)