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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40
NCBI: 02-MAR-2017
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus USA300_FPR3757
- locus tag: SAUSA300_RS00365 [old locus tag: SAUSA300_0072 ]
- pan locus tag?: SAUPAN000820000
- symbol: SAUSA300_RS00365
- pan gene symbol?: —
- synonym:
- product: methyltransferase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SAUSA300_RS00365 [old locus tag: SAUSA300_0072 ]
- symbol: SAUSA300_RS00365
- product: methyltransferase
- replicon: chromosome
- strand: +
- coordinates: 79705..80397
- length: 693
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_007793 (79705..80397) NCBI
- BioCyc: see SAUSA300_0072
- MicrobesOnline: see SAUSA300_0072
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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661ATGACTAAGACTTATGACGTTTGGTGGCAAAAAGGTCAAGAATCAGATGATGATATGGCA
CGAGACCATCAAGAAGCTTGGGAGAGAACAATAAAAATGCTTGATACATCTGACATCGAA
GGGAAAACGATTTTAGATGTGGGATGTAATCAAGGCGGATTTTTACGACAGTTATACGAT
ACAACACCGTTTAAAAAAGGTGTTGGCATAGATTTAGCACGTTTATCTTTGGAAAAGGCA
GAGACATTAAAAGGACAACGTCCACTTACATACTATTTAACAGATAAACCGCAAGAAACG
AAGCACGTGTTTGATACGGCAGTAAGTACGTCTGTCTTGTACTTAATAGAAGATATTCCG
CAACATGCAAAAGATTTAAAAGAGGTATTGAAACCAGGCGGTGTTTATTACGCTTCATTC
GCGGATTTAACTAATAACCCAAGTCGTCAGTTTATGGATGACACGATTAATCAATATGGT
GCAACACCTTCTCAGAATCACTCTCTAAAACATATCGTTGATAGCTTTGTGGATGCAGGA
TTTGAAGTTGCAGTAATGAAAGAGCATGTACCTGACGTGATTGATTTAACACATTATAGC
GATTTTTATTTATCACCGAATGATTATTTACAAACACTATATGAAGAATCGTTTTTAATA
AAAGCAAGTGTGAAAGAAGGTACTGAGAAATGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SAUSA300_RS00365 [old locus tag: SAUSA300_0072 ]
- symbol: SAUSA300_RS00365
- description: methyltransferase
- length: 230
- theoretical pI: 4.6315
- theoretical MW: 26232.2
- GRAVY: -0.571304
⊟Function[edit | edit source]
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Biotin malonyl-acyl carrier protein O-methyltransferase BioC (TIGR02072; EC 2.1.1.-; HMM-score: 35.4)Unknown function Enzymes of unknown specificity tRNA (mo5U34)-methyltransferase (TIGR00452; EC 2.1.1.-; HMM-score: 30.9)Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 3-demethylubiquinone-9 3-O-methyltransferase (TIGR01983; EC 2.1.1.64; HMM-score: 30.8)and 10 moreTranscription RNA processing 3' terminal RNA ribose 2'-O-methyltransferase Hen1 (TIGR04074; EC 2.1.1.-; HMM-score: 20.1)Protein synthesis tRNA and rRNA base modification 3' terminal RNA ribose 2'-O-methyltransferase Hen1 (TIGR04074; EC 2.1.1.-; HMM-score: 20.1)2-ketoarginine methyltransferase (TIGR04543; EC 2.1.1.243; HMM-score: 19.8)pseudaminic acid biosynthesis-associated methylase (TIGR03587; HMM-score: 18.8)methyltransferase, Rta_06860 family (TIGR04290; EC 2.1.1.-; HMM-score: 18.5)Biosynthesis of cofactors, prosthetic groups, and carriers Chlorophyll and bacteriochlorphyll magnesium protoporphyrin O-methyltransferase (TIGR02021; EC 2.1.1.11; HMM-score: 18.2)Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs putative 4-mercaptohistidine N1-methyltranferase (TIGR04345; HMM-score: 18.1)Amino acid biosynthesis Aspartate family methionine biosynthesis protein MetW (TIGR02081; HMM-score: 14)Protein synthesis tRNA and rRNA base modification tRNA (guanine-N(7)-)-methyltransferase (TIGR00091; EC 2.1.1.33; HMM-score: 12.1)Unknown function General TlyA family rRNA methyltransferase/putative hemolysin (TIGR00478; HMM-score: 11.3)
- TheSEED: see SAUSA300_0072
- PFAM: NADP_Rossmann (CL0063) Methyltransf_23; Methyltransferase domain (PF13489; HMM-score: 49)Methyltransf_31; Methyltransferase domain (PF13847; HMM-score: 41.2)Methyltransf_11; Methyltransferase domain (PF08241; HMM-score: 39.2)and 9 moreMethyltransf_12; Methyltransferase domain (PF08242; HMM-score: 37.6)Methyltransf_25; Methyltransferase domain (PF13649; HMM-score: 33.3)Methyltransf_9; Protein of unknown function (DUF1698) (PF08003; HMM-score: 28.1)NodS; Nodulation protein S (NodS) (PF05401; HMM-score: 20.8)FtsJ; FtsJ-like methyltransferase (PF01728; HMM-score: 13.3)Uteroglobin (CL0370) Feld-I_B; Allergen Fel d I-B chain (PF09252; HMM-score: 12.8)NADP_Rossmann (CL0063) Methyltransf_18; Methyltransferase domain (PF12847; HMM-score: 12.2)CMAS; Mycolic acid cyclopropane synthetase (PF02353; HMM-score: 12)Methyltransf_4; Putative methyltransferase (PF02390; HMM-score: 11.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.020523
- TAT(Tat/SPI): 0.000511
- LIPO(Sec/SPII): 0.001954
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI: 446091729 NCBI
- RefSeq: WP_000169584 NCBI
- UniProt: see SAUSA300_0072
⊟Protein sequence[edit | edit source]
- MTKTYDVWWQKGQESDDDMARDHQEAWERTIKMLDTSDIEGKTILDVGCNQGGFLRQLYDTTPFKKGVGIDLARLSLEKAETLKGQRPLTYYLTDKPQETKHVFDTAVSTSVLYLIEDIPQHAKDLKEVLKPGGVYYASFADLTNNPSRQFMDDTINQYGATPSQNHSLKHIVDSFVDAGFEVAVMKEHVPDVIDLTHYSDFYLSPNDYLQTLYEESFLIKASVKEGTEK
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: no data available
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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