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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS05125 [old locus tag: SAUSA300_0954 ]
  • pan locus tag?: SAUPAN003258000
  • symbol: SAUSA300_RS05125
  • pan gene symbol?:
  • synonym:
  • product: MarR family transcriptional regulator

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS05125 [old locus tag: SAUSA300_0954 ]
  • symbol: SAUSA300_RS05125
  • product: MarR family transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 1043593..1044012
  • length: 420
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGTATAAACAACTTGAAAAACTTATTACACTGACTAACAATGACTTAAACTTAGTGAAT
    AGAAGATTTGGACAACGCACGGATATCAAATCTGAACAGCTAGAACTTCTCCGTATTTTA
    TTTAATTACGATCGCTTATCACAGTATGATTTGACGATGAAGATTAGCAGGGAACAATCT
    ATAGTTTCAAGGTGGATTAAGAAATTAGTTTTGAAAGGGTACATCACAAGTCAACAATCT
    AGCGAAGATTTAAGATGTAAAGAATTAATTTTGACTGATCAAGCACGTACATTAATTTCA
    CAAATAAATAATGCACGTTGCGAATTGATTGAAGCAAGATGTCAATGTTTATCGGAAGTC
    GAATTAGACAATTTAAATCAATTACTTGATAAGTTAAATCAACGACGCATATCGTTGTAA
    60
    120
    180
    240
    300
    360
    420

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_RS05125 [old locus tag: SAUSA300_0954 ]
  • symbol: SAUSA300_RS05125
  • description: MarR family transcriptional regulator
  • length: 139
  • theoretical pI: 8.93819
  • theoretical MW: 16477
  • GRAVY: -0.457554

Function[edit | edit source]

  • TIGRFAM:
    homoprotocatechuate degradation operon regulator, HpaR (TIGR02337; HMM-score: 26.3)
    and 2 more
    mobile rSAM pair MarR family regulator (TIGR04472; HMM-score: 19.2)
    Signal transduction Regulatory functions DNA interactions staphylococcal accessory regulator family (TIGR01889; HMM-score: 15.4)
  • TheSEED: see SAUSA300_0954
  • PFAM:
    HTH (CL0123) MarR; MarR family (PF01047; HMM-score: 50.6)
    and 4 more
    MarR_2; MarR family (PF12802; HMM-score: 25.8)
    HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 24.3)
    TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 17.9)
    HTH_36; Helix-turn-helix domain (PF13730; HMM-score: 14.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002792
    • TAT(Tat/SPI): 0.000236
    • LIPO(Sec/SPII): 0.000289
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MYKQLEKLITLTNNDLNLVNRRFGQRTDIKSEQLELLRILFNYDRLSQYDLTMKISREQSIVSRWIKKLVLKGYITSQQSSEDLRCKELILTDQARTLISQINNARCELIEARCQCLSEVELDNLNQLLDKLNQRRISL

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]