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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS06335 [old locus tag: SAUSA300_1171 ]
  • pan locus tag?: SAUPAN003579000
  • symbol: SAUSA300_RS06335
  • pan gene symbol?:
  • synonym:
  • product: peptidase M16

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS06335 [old locus tag: SAUSA300_1171 ]
  • symbol: SAUSA300_RS06335
  • product: peptidase M16
  • replicon: chromosome
  • strand: +
  • coordinates: 1289440..1290705
  • length: 1266
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    TTGAGTAGACAATCTCAACCAAATATACATATCAAAGTTTCACCAACAACTAAATTTAAA
    ACAACTACTATAGTTTTTAAATTTATGGCACCTTTAGAATATGACACAATAACAGCTAGA
    TCATTATTAAGCAAATTATTAGTTCGAGCAACTAAGAAATGGCCAACCGATAAGTCGTTT
    AATAATCACTTAGCCGATTTATATGGTGCGTATGTGAATAGTACAATTTCAAAATTCAAA
    GATCAGCATGTCATTACATTTTCATTAGAAATTGTTAATGAACGTTATTTAAGAAACGGT
    GAATCATTATTTAATCAAGGATTAGATTTATTACAAGAAATCATTTGGAATCCATTAATT
    GAAAATAAAGCATTCAATGATAATTTTGTTAACCAAGAGAAAACATTATTAGCCAAAAAA
    ATAGAAGCAATGGTAGATAATAAAGCACAATATTCGTTTTTAAAATTACTCGACCATATG
    TTTGAAAATGAAGCATATAAATACTTATCTACAGGACAACTAGAACAAATCCCACATATT
    ACTGCTGAAACACTATATCATACATATCAATCAATGATTAATAATGATCAATGTTCTGTT
    TATGTTGTCGGCAATGTAGAACCTGAAAGTGTTGAGAAACAAATACGTGAAAAATTTGCA
    CTTAAACCATTCGATAAACATCAATTCCAACATTCTACTCATCATTTACACGATGAAGAA
    GTTGATTATATTGTTGAATATGATGACGTGGATCAAGCTAAATTAAATATGGGATACCGT
    TTTCCAACACAATATGGACAAAGTGGATATGCTGCCTTTGTTGTATTTAACATGATGTTT
    GGAGGAGATCCTTCATCTGTTTTATTTAATGAAGTGCGAGAAAAGCAAAGTTTAGCGTAC
    TCTATACATTCACAAATTGATGGCAAAAATGGCTATTTATTTGTTTTGAGTGGGGTTTCA
    AGTGATAAGTACGAAACTGCAAAAGACACTATTATAAGTGAATTTGAAAAAATAAAAGCA
    GGAGATTTCACTGAAGAAAAATTAGAGTTAGCTAAAAAAGTAATCATTTCTCATCGATAT
    GAATCTGAAGATCGTCCGAAAAGTATTATAGAGATTATGCATAACCAAATATTATTAGAG
    CAACCACAAAGCAAAGAAACATTTATAAATGATATACAGAAGGTAAGTCGCGAAGATATT
    GTTTCTGTTGCTGAAAAAGCATTTTTAGATACAATCTATGTGTTGACAAAAGGAGGGGAT
    AAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1266

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_RS06335 [old locus tag: SAUSA300_1171 ]
  • symbol: SAUSA300_RS06335
  • description: peptidase M16
  • length: 421
  • theoretical pI: 6.03414
  • theoretical MW: 48617.7
  • GRAVY: -0.454632

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SAUSA300_1171
  • PFAM:
    Peptidase_ME (CL0094) Peptidase_M16_C; Peptidase M16 inactive domain (PF05193; HMM-score: 97.9)
    and 2 more
    Peptidase_M16; Insulinase (Peptidase family M16) (PF00675; HMM-score: 18.2)
    no clan defined Peptidase_M29; Thermophilic metalloprotease (M29) (PF02073; HMM-score: 14.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006709
    • TAT(Tat/SPI): 0.000717
    • LIPO(Sec/SPII): 0.000537
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MSRQSQPNIHIKVSPTTKFKTTTIVFKFMAPLEYDTITARSLLSKLLVRATKKWPTDKSFNNHLADLYGAYVNSTISKFKDQHVITFSLEIVNERYLRNGESLFNQGLDLLQEIIWNPLIENKAFNDNFVNQEKTLLAKKIEAMVDNKAQYSFLKLLDHMFENEAYKYLSTGQLEQIPHITAETLYHTYQSMINNDQCSVYVVGNVEPESVEKQIREKFALKPFDKHQFQHSTHHLHDEEVDYIVEYDDVDQAKLNMGYRFPTQYGQSGYAAFVVFNMMFGGDPSSVLFNEVREKQSLAYSIHSQIDGKNGYLFVLSGVSSDKYETAKDTIISEFEKIKAGDFTEEKLELAKKVIISHRYESEDRPKSIIEIMHNQILLEQPQSKETFINDIQKVSREDIVSVAEKAFLDTIYVLTKGGDK

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]