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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS08765 [old locus tag: SAUSA300_1609 ]
  • pan locus tag?: SAUPAN004272000
  • symbol: SAUSA300_RS08765
  • pan gene symbol?: comC
  • synonym:
  • product: prepilin peptidase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS08765 [old locus tag: SAUSA300_1609 ]
  • symbol: SAUSA300_RS08765
  • product: prepilin peptidase
  • replicon: chromosome
  • strand: -
  • coordinates: 1760212..1760919
  • length: 708
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    TTGGTAGTATTGTTATCTTATAGTTGCAGTTGTATTTTTAGTTTTCTATATCAATTTATA
    TCTATAGAAGAAACGTCATTTGATTATTTACATAGAAGATCGAAATGTGATTATTGTAAT
    TCGTCACTCAAATGGTATGAATTAATGCCGATTATTAGTTTTTTATTATTAAAAGGGCGA
    TGTCGAAACTGTCGAAAGCGTATTTCCCTAACACATTTCTTAGGGGAAACCTTTGCTTTA
    ATACCTATCGTCTTTATTAAGTATGATTTCACATACGTAAATGCTACGCTATTTATAACT
    ACATATGTTTTTCTGCTTATTTTTACTATGACCGATATCACTTCTTTAATGTTAGATTGT
    CGCTTAATTATAATTTATTGTATCGTTTCTCTCTCGTTAAGTATGATTTATCCAGTAGCT
    TTTATCATTATTAGTATGACCACGCATATATTCTACTTTTTATTTCGGGCATATATTGGT
    TATGGTGACGTTTTACTAATATCTGCACTTTCTTTGTTTTTCCCTCTCCAATTCACTATT
    TATGTCATTTTATTTACATTTGTCATTGCTGGTTTAGTTGCTTTAATTACCATGATATTT
    AAGCCGATTAAACTATTACCCCTTGTTCCATTTATATTTATTTCCTTTTTTATCAATTCA
    CTTTTTTATAATGATATCCATCAATTTTTAGGAGGCGTATATTTTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    708

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_RS08765 [old locus tag: SAUSA300_1609 ]
  • symbol: SAUSA300_RS08765
  • description: prepilin peptidase
  • length: 235
  • theoretical pI: 8.36288
  • theoretical MW: 27504
  • GRAVY: 1.0834

Function[edit | edit source]

  • TIGRFAM:
    cxxc_20_cxxc protein (TIGR04104; HMM-score: 17.7)
  • TheSEED: see SAUSA300_1609
  • PFAM:
    no clan defined DiS_P_DiS; Bacterial Peptidase A24 N-terminal domain (PF06750; HMM-score: 69.6)
    and 2 more
    Peptidase_AD (CL0130) Peptidase_A24; Type IV leader peptidase family (PF01478; HMM-score: 15.6)
    Zn_Beta_Ribbon (CL0167) DZR; Double zinc ribbon (PF12773; HMM-score: 13)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.082256
    • TAT(Tat/SPI): 0.004679
    • LIPO(Sec/SPII): 0.017514
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MVVLLSYSCSCIFSFLYQFISIEETSFDYLHRRSKCDYCNSSLKWYELMPIISFLLLKGRCRNCRKRISLTHFLGETFALIPIVFIKYDFTYVNATLFITTYVFLLIFTMTDITSLMLDCRLIIIYCIVSLSLSMIYPVAFIIISMTTHIFYFLFRAYIGYGDVLLISALSLFFPLQFTIYVILFTFVIAGLVALITMIFKPIKLLPLVPFIFISFFINSLFYNDIHQFLGGVYF

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]