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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS11475 [old locus tag: SAUSA300_2084 ]
  • pan locus tag?: SAUPAN005426000
  • symbol: SAUSA300_RS11475
  • pan gene symbol?: coaA
  • synonym:
  • product: type II pantothenate kinase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS11475 [old locus tag: SAUSA300_2084 ]
  • symbol: SAUSA300_RS11475
  • product: type II pantothenate kinase
  • replicon: chromosome
  • strand: +
  • coordinates: 2247009..2247812
  • length: 804
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAAAGTTGGCATTGACGCTGGCGGTACACTAATTAAAATCGTTCAAGAGCAAGATAAC
    CAACGTACTTTTAAAACTGAATTAACTAAAAATATTGATCAAGTTGTGGAATGGTTAAAC
    CAACAGCAAATTGAAAAATTATGCTTAACTGGAGGTAATGCAGGTGTCATTGCTGAAAAC
    ATCAACATTCCTGCACAAATTTTTGTAGAGTTTGATGCTGCATCTCAAGGACTAGGTATT
    TTGTTAAAAGAGCAAGGCCATGACTTAGCAGATTATATTTTTGCAAATGTTGGTACCGGT
    ACGTCACTACATTATTTCGACGGCCAATCACAACGTCGTGTAGGCGGTATCGGTACAGGT
    GGAGGCATGATTCAAGGACTCGGTTATTTACTAAGTCAAATCACTGATTATAAACAGTTA
    ACTGACATGGCACAACACGGTGATCGTAACACTATCGATTTAAAGGTTAGACATATTTAT
    AAAGATACCGAACCACCCATTCCCGGTGATTTAACAGCAGCTAATTTTGGTCATGTACTA
    CATCATTTAGATGCTGATTTTACACCTAGCAATAAATTAGCAGCCGTTATTGGTGTCGTT
    GGCGAAGTTGTTACGACAATGGCCATTACTGTTGCACGTGAATTTAAAACTGAAAATATC
    GTTTATATCGGTTCTTCATTTCATAATAACGCTTTATTACGCAAAGTTGTGGAAGATTAT
    ACTGTGTTACGCGGTTGCAAACCGTACTATGTTGAAAACGGCGCATTTTCAGGTGCTATT
    GGTGCATTATATTTAGAAAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    804

⊟Protein[edit | edit source]

Protein Data Bank: 5ELZ
Protein Data Bank: 5JIC

⊟General[edit | edit source]

  • locus tag: SAUSA300_RS11475 [old locus tag: SAUSA300_2084 ]
  • symbol: SAUSA300_RS11475
  • description: type II pantothenate kinase
  • length: 267
  • theoretical pI: 5.55856
  • theoretical MW: 29096.8
  • GRAVY: -0.0988764

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.1.33?  ExPASy
    Pantothenate kinase ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate
  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A pantothenate kinase (TIGR00555; EC 2.7.1.33; HMM-score: 314.4)
    and 2 more
    Metabolism Amino acid biosynthesis Serine family cysteine synthase (TIGR01136; EC 2.5.1.47; HMM-score: 14.5)
    Metabolism Amino acid biosynthesis Serine family cysteine synthase A (TIGR01139; EC 2.5.1.47; HMM-score: 12.5)
  • TheSEED: see SAUSA300_2084
  • PFAM:
    Actin_ATPase (CL0108) Fumble; Fumble (PF03630; HMM-score: 86.6)
    and 1 more
    BcrAD_BadFG; BadF/BadG/BcrA/BcrD ATPase family (PF01869; HMM-score: 13.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.018811
    • TAT(Tat/SPI): 0.001751
    • LIPO(Sec/SPII): 0.000446
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLEK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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