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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS12670 [old locus tag: SAUSA300_2293 ]
  • pan locus tag?: SAUPAN005846000
  • symbol: SAUSA300_RS12670
  • pan gene symbol?: corA
  • synonym:
  • product: cobalt transporter CorA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS12670 [old locus tag: SAUSA300_2293 ]
  • symbol: SAUSA300_RS12670
  • product: cobalt transporter CorA
  • replicon: chromosome
  • strand: -
  • coordinates: 2465682..2466629
  • length: 948
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGCTTTAAAGATACGGTATCAAACTACATATGAACCGTTTAAAGTAGTTGATGATATC
    AAAGAGATACCAAAAGATGCGACTATTGTTTGGTATGATTTTGATGAACCGAATGAACAA
    GAAAATGAATGGTTTAAAGCACATTTTAATTTTAATGATTTAGAAGTGGATGATGCAATT
    AACGGTATGCCACGAGCTAAATATAAATCTTATAAAGATTATCAATACTTAGTATTCCAT
    AGTATTATGGGGTCAAACTATTCACCAATAGCACTAAATATTTTTATACAAGACAATGTA
    TTAGTAACATATCATCATCAAACGTTGGAATCATTAAATAAAGTAGTCTATAAGTATATG
    AATACATTAGATGCAGAATTAGATTGTGCAGATGTCGTCATATTAATTTTAGATATGATG
    GTTGATAAATATTTCAACTTTGTATATGCACTTGAAGATAGTGTTTATCATTTTGAAGAC
    CGCCATGTAGATGATCGCTTTAATAAAATGGTCATGGATAGTGTCTTTAAGTTACGTTCG
    GATTTGATTAAAGTAAAACGTGTACTGTTTCCTATGCAAGAGCTAATTGATACAATGAAA
    CAAAATGGTGATTTGATTATAGATAATAAACATTCGCTATACATTCAACATATCGATGAC
    CACTTGATTAAGCAACGTAATATCATTCGTACTGCTCAAGAAATGACAAACGAAATACGA
    GAAAATTTTGAGTCATACACGTCATTTAGAATGAATAGTATTATGCAAGTACTGACATTA
    GTATCAGTTATATTTTCACCGTTAACATTCATAGCTGGGATTTATGGTATGAACTTTGTA
    AATATGCCGGCATTACATTTACATTATGGATATTATATTTGCTTAGCTGTAATGTTTGTT
    ATAGCTGTCGTATTAATCATCTTTTTCAGACGTAAAAAATGGTTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    948

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SAUSA300_RS12670 [old locus tag: SAUSA300_2293 ]
  • symbol: SAUSA300_RS12670
  • description: cobalt transporter CorA
  • length: 315
  • theoretical pI: 5.76074
  • theoretical MW: 37526.2
  • GRAVY: -0.067619

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds magnesium and cobalt transport protein CorA (TIGR00383; HMM-score: 206.9)
  • TheSEED: see SAUSA300_2293
  • PFAM:
    no clan defined CorA; CorA-like Mg2+ transporter protein (PF01544; HMM-score: 244.6)
    and 6 more
    DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 17.9)
    Transporter (CL0375) Claudin_2; PMP-22/EMP/MP20/Claudin tight junction (PF13903; HMM-score: 13.9)
    GAG-polyprotein (CL0523) Retrotran_gag_2; gag-polypeptide of LTR copia-type (PF14223; HMM-score: 13.5)
    no clan defined SlyX; SlyX (PF04102; HMM-score: 13.4)
    Tetraspannin (CL0347) Tetraspannin; Tetraspanin family (PF00335; HMM-score: 11.2)
    RND_permease (CL0322) MMPL; MMPL family (PF03176; HMM-score: 8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.04
    • Cytoplasmic Membrane Score: 9.96
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 2
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002887
    • TAT(Tat/SPI): 0.00014
    • LIPO(Sec/SPII): 0.000381
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MALKIRYQTTYEPFKVVDDIKEIPKDATIVWYDFDEPNEQENEWFKAHFNFNDLEVDDAINGMPRAKYKSYKDYQYLVFHSIMGSNYSPIALNIFIQDNVLVTYHHQTLESLNKVVYKYMNTLDAELDCADVVILILDMMVDKYFNFVYALEDSVYHFEDRHVDDRFNKMVMDSVFKLRSDLIKVKRVLFPMQELIDTMKQNGDLIIDNKHSLYIQHIDDHLIKQRNIIRTAQEMTNEIRENFESYTSFRMNSIMQVLTLVSVIFSPLTFIAGIYGMNFVNMPALHLHYGYYICLAVMFVIAVVLIIFFRRKKWF

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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