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Pangenome04-0298108BA0217611819-97685071193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS00490 [old locus tag: SA0068 ]
  • pan locus tag?: SAUPAN000456000
  • symbol: SA_RS00490
  • pan gene symbol?: kdpA
  • synonym:
  • product: potassium-transporting ATPase subunit A

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS00490 [old locus tag: SA0068 ]
  • symbol: SA_RS00490
  • product: potassium-transporting ATPase subunit A
  • replicon: chromosome
  • strand: +
  • coordinates: 77116..78792
  • length: 1677
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_002745 (77116..78792) NCBI
  • BioCyc: G1G21-73 BioCyc
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
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    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGAGTATTGTGTTGTTTTTGATTGTATTTATCTTGCTCTCACTCATTGTGAGCCGATAT
    TTATATTCAGTTGCTTTAAATGTGCCATCTAAAATAGATGTTGTTTTTAATCCGATTGAG
    AAATTGATTTATCAACTGATTGGCACGAAATTAGAACACATGTCTGGGAAGACGTATATC
    AAACATTTTTTGTTGTTTAACGGATTGATGGGCGGATTGTCCTTTGTATTATTGCTTATT
    CAACAATGGCTGTTTTTGAATCCTAACCATAATTTAAATCAATCTGTATCGTTAGCCTTT
    AATACTATGGCATCTTTTTTGACCAATACTAACTTACAGCATTATGCAGGTGAAACAGAT
    TTAAGTTATTTAACACAAATGTGTGTCATCACTTTCTTAATGTTCACGTCAGCAGCGTCA
    GGTTACGCCGTATGTATTGCGATGTTAAGACGTTTGACTGGAATGACAGATGTGATTGGT
    AATTTCTATCAAGATATTACGCGTTTTATTGTACGGGTGCTCATACCTTTCGCATTGATC
    ATCAGTTTGTTTTTAATCAGTCAGGGCACACCGCAAACGCTTAAAGGTAATTTGGTGATT
    GAGACATTATCAGGTGTGAAACAAACGATTGCATATGGACCGATGGCGTCTTTAGAATCT
    ATTAAACATTTAGGGACAAATGGTGGTGGTTTCTTAGGTGCGAACTCTTCTACACCTTTT
    GAAAATCCGACATACTGGTCTAATTACGCTGAAGCTTTAAGTATGATGTTGATTCCAGGT
    TCATTAGTCTTTCTATTCGGTAGAATGTTGAAAACTAAACTACAGATTCATCCGCATGCG
    ATTATGATTTTCGTTGCGATGTTTGTAATGTTCATCGGCTTTTTAGTGACATGTCTCTAT
    TTTGAATTTGCGGGGAATCCAGTGTTGCATCACTTAGGTATTGCCGGTGGCAATATGGAA
    GGCAAAGAAACACGTTTCGGTATTGGCTTATCCGCTTTATTTACAACCATTACGACCGCT
    TTTACTACAGGAACAGTTAACAATATGCACGATAGTCTTACACCGCTAGGCGGCATGGTT
    CCAATGGTATTAATGATGTTGAATGCAGTTTTTGGCGGTGAAGGTGTTGGGCTGATGAAC
    ATGTTGATTTATGTCATGTTAACGGTCTTTATCTGTAGTTTGATGATTGGGAAAACACCA
    AGTTATTTAGGAATGAAGATTGAAGGTAAAGAGATGAAACTCATTGCGCTTTCTTTCTTA
    GTACATCCTTTACTTATTTTGGTTTTTTCAGCACTAGCTTTTATTGTGCCAGGGGCATCA
    GATGCGTTAACTAATCCGCAATTCCACGGTGTATCACAAGTGTTGTATGAGTTTACATCA
    TCTTCAGCGAATAATGGCTCTGGTTTTGAAGGATTAGGAGACAATACGGTATTTTGGAAC
    ATTTCAACAGGCATTGTGATGTTGCTTGCACGATATATTCCAATCGTTTTACAAATTTTG
    ATTGTATCTAGTTTGGTAAATAAAAAGACCTATCAGCAACATACTCAAGATGTACCGATT
    AATAATTTATTTTTCAGCAGTGTATTGATTATCTTTATTATTTTGTTGAGCGGCTTAACG
    TTCTTACCTGACTTAATGCTTGGACCAATAGGCGAACAGCTTTTGCTGCACGCATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
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    720
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    840
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    960
    1020
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    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1677

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS00490 [old locus tag: SA0068 ]
  • symbol: SA_RS00490
  • description: potassium-transporting ATPase subunit A
  • length: 558
  • theoretical pI: 7.72916
  • theoretical MW: 61262.4
  • GRAVY: 0.72276

Function[edit | edit source]

  • reaction:
    EC 3.6.3.12?  ExPASy
    Potassium-transporting ATPase ATP + H2O + K+(Out) = ADP + phosphate + K+(In)
  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds K+-transporting ATPase, A subunit (TIGR00680; EC 3.6.3.12; HMM-score: 588.1)
  • TheSEED:
  • PFAM:
    Ion_channel (CL0030) KdpA; Potassium-transporting ATPase A subunit (PF03814; HMM-score: 716.7)
    and 1 more
    CopD_like (CL0430) DUF4149; Domain of unknown function (DUF4149) (PF13664; HMM-score: 14.7)

Structure, modifications & interactions[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.256215
    • TAT(Tat/SPI): 0.002539
    • LIPO(Sec/SPII): 0.025806
  • predicted transmembrane helices (TMHMM): 12

Accession numbers[edit | edit source]

  • GI: 445951575 NCBI
  • RefSeq: WP_000029430 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MSIVLFLIVFILLSLIVSRYLYSVALNVPSKIDVVFNPIEKLIYQLIGTKLEHMSGKTYIKHFLLFNGLMGGLSFVLLLIQQWLFLNPNHNLNQSVSLAFNTMASFLTNTNLQHYAGETDLSYLTQMCVITFLMFTSAASGYAVCIAMLRRLTGMTDVIGNFYQDITRFIVRVLIPFALIISLFLISQGTPQTLKGNLVIETLSGVKQTIAYGPMASLESIKHLGTNGGGFLGANSSTPFENPTYWSNYAEALSMMLIPGSLVFLFGRMLKTKLQIHPHAIMIFVAMFVMFIGFLVTCLYFEFAGNPVLHHLGIAGGNMEGKETRFGIGLSALFTTITTAFTTGTVNNMHDSLTPLGGMVPMVLMMLNAVFGGEGVGLMNMLIYVMLTVFICSLMIGKTPSYLGMKIEGKEMKLIALSFLVHPLLILVFSALAFIVPGASDALTNPQFHGVSQVLYEFTSSSANNGSGFEGLGDNTVFWNISTGIVMLLARYIPIVLQILIVSSLVNKKTYQQHTQDVPINNLFFSSVLIIFIILLSGLTFLPDLMLGPIGEQLLLHA

Experimental data[edit | edit source]

  • experimentally validated: no data available

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]