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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS00565 [old locus tag: SA0082 ]
  • pan locus tag?: SAUPAN000487000
  • symbol: SA_RS00565
  • pan gene symbol?: cstA
  • synonym:
  • product: dihydroneopterin aldolase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS00565 [old locus tag: SA0082 ]
  • symbol: SA_RS00565
  • product: dihydroneopterin aldolase
  • replicon: chromosome
  • strand: +
  • coordinates: 91521..92585
  • length: 1065
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_002745 (91521..92585) NCBI
  • BioCyc: G1G21-89 BioCyc
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAAACAATACGGAGAAAAGTTTATCGATGAATTTAGTAAAGCAGAATTGGAAAAACTA
    GCCAAGCAAGGGCAATTAATTGATGTTAGAACAGAAGAGGAGTATGCATTAGGACATATC
    AATGGTTCCATACTTCATCCTGTTGATGAGATTGAGTCATTCAATAAAGAAAAAAATAAA
    ACCTATTATGTAATCTGTAGAAGTGGTAACAGAAGTGCTAATGCTAGTAAATATTTAGCT
    AAACAAGGTTATAACGTTATAAATCTTGATGGTGGTTATAAAGCTTATGAAGAAAACGAT
    AGTTATGATACACAAGAAGAATATAAAAGTATAGAAATTAAAGCAGATCGTAAACAATTT
    AACTATCGTGGTTTTCAATGTCCAGGGCCAATTGTAAAAATTAGTCAAGAAATGAAGAAT
    ATTGAAGTAGGTGACCAAATTGAAGTCAAAGTCACAGACCCTGGATTCCCTAGTGATATT
    AAAAGTTGGGTGAAACAAACAAGGCATACTTTAGTTAAGCTTGATGAAAATAACAATGGA
    ATTAATGCGATTATTCAAAAAGAAAAAGCAAAAGATTTAGATATAAATTATTCTGCTAAA
    GGTACTACAATTGTATTATTTAGTGGAGAATTAGACAAAGCTGTAGCAGCATTGATTATT
    GCAAATGGCGCTAGAGCTGCTGGAAAAGATGTAACTATCTTCTTTACTTTTTGGGGGCTT
    AATGCATTAAAAAAAGTGCAAACAGTTAATGTTAAAAAGCAAGGTATTGCAAAAATGTTT
    GATTTAATGTTGCCCCAAAAGAATATACGAATGCCTCTTTCCAAAATGAATATGTTTGGT
    TTAGGAAATATGATGATGCGCTACGTAATGAAAAAGAAAAATGTTGATTCATTACCAACA
    CTTATCAATCAAGCTATTGAGCAAAATATCAAATTAATCGCTTGTACGATGAGTATGGAT
    GTCATGGGTATTCAGAAAGAAGAACTTAGAGATGAAGTTGAGTACGGTGGTGTAGGCACT
    TATATTGGTGCTACTGAAAATGCGAATCATAATTTATTTATCTAA
    60
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    1020
    1065

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS00565 [old locus tag: SA0082 ]
  • symbol: SA_RS00565
  • description: dihydroneopterin aldolase
  • length: 354
  • theoretical pI: 8.36755
  • theoretical MW: 39991.7
  • GRAVY: -0.441243

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA 2-selenouridine synthase (TIGR03167; EC 2.9.1.-; HMM-score: 36.9)
    phage shock operon rhodanese PspE (TIGR02981; EC 2.8.1.1; HMM-score: 31.5)
    and 2 more
    selenium metabolism protein YedF (TIGR03527; HMM-score: 21.7)
    thiazole biosynthesis domain (TIGR04271; HMM-score: 12.9)
  • TheSEED:
  • PFAM:
    DsrEFH-like (CL0394) DrsE_2; DsrE/DsrF/DrsH-like family (PF13686; HMM-score: 195.4)
    and 4 more
    TusA-like (CL0397) TusA; Sulfurtransferase TusA (PF01206; HMM-score: 68.3)
    Phosphatase (CL0031) Rhodanese; Rhodanese-like domain (PF00581; HMM-score: 59.2)
    DsrEFH-like (CL0394) DrsE; DsrE/DsrF-like family (PF02635; HMM-score: 40.4)
    6_Hairpin (CL0059) Prenyltrans; Prenyltransferase and squalene oxidase repeat (PF00432; HMM-score: 11.7)

Structure, modifications & interactions[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005604
    • TAT(Tat/SPI): 0.001709
    • LIPO(Sec/SPII): 0.001465
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI: 446738877 NCBI
  • RefSeq: WP_000816133 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MKQYGEKFIDEFSKAELEKLAKQGQLIDVRTEEEYALGHINGSILHPVDEIESFNKEKNKTYYVICRSGNRSANASKYLAKQGYNVINLDGGYKAYEENDSYDTQEEYKSIEIKADRKQFNYRGFQCPGPIVKISQEMKNIEVGDQIEVKVTDPGFPSDIKSWVKQTRHTLVKLDENNNGINAIIQKEKAKDLDINYSAKGTTIVLFSGELDKAVAALIIANGARAAGKDVTIFFTFWGLNALKKVQTVNVKKQGIAKMFDLMLPQKNIRMPLSKMNMFGLGNMMMRYVMKKKNVDSLPTLINQAIEQNIKLIACTMSMDVMGIQKEELRDEVEYGGVGTYIGATENANHNLFI

Experimental data[edit | edit source]

  • experimentally validated: no data available

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]