From AureoWiki
Jump to navigation Jump to search

NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS01240 [old locus tag: SA0211 ]
  • pan locus tag?: SAUPAN001070000
  • symbol: SA_RS01240
  • pan gene symbol?: —
  • synonym:
  • product: gfo/Idh/MocA family oxidoreductase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS01240 [old locus tag: SA0211 ]
  • symbol: SA_RS01240
  • product: gfo/Idh/MocA family oxidoreductase
  • replicon: chromosome
  • strand: +
  • coordinates: 250117..251157
  • length: 1041
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (250117..251157) NCBI
  • BioCyc: SA_RS01240 BioCyc
  • MicrobesOnline: see SA0211

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGACAAAATTAAAAGTTGGTGTGATAGGTGTTGGTGGCATTGCACAAGACCGTCATATT
    CCAGCATTGCTGAAACTCAAAGACACAGTCTCATTAGTTGCAGTACAAGATATTAATACA
    GTGCAGATGATTGATGTTGCGAAGCGCTTTAATATACCTCAGGCAGTTGAGACACCTAGC
    GAGCTGTTTAAACTTGTTGATGCGGTGGTCATTTGTACACCCAATAAATTCCATGCTGAT
    CTTTCTATAGAAGCATTGAACCATGGTGTCCATGTCTTATGCGAAAAGCCAATGGCAATG
    ACGACGGAAGAGTGTGATCGCATGATTGAAGCGGCTAATAAAAATCACAAATTATTAACT
    GTCGCTTATCATTATCGTCACACAGATGTCGCTATGACTGCTAAAAAAGCAATTGAAGCA
    GGTGTGGTTGGTAAACCATTAGTAGCACGTGTACAAGCGATGCGTAGGCGTAAAGTACCT
    GGGTGGGGCGTTTTTACCAATAAAGCGTTGCAAGGTGGCGGTAGTTTAATCGATTATGGT
    TGCCACTTGTTAGACTTATCTTTGTGGCTATTAGGTAAAGATATGGTGCCGCATGAAGTG
    CTAGGAAAAACATATAATCAATTGAGCAAACAACCGAATCAAATTAATGATTGGGGAACA
    TTTGATCACACTAAATTTGATGTCGATGATCATGTTACTAGTTATATGACATTTGCCAAT
    CGAGCAAGCATGCAGTTTGAATGTTCGTGGTCTGCAAATATAAAGGAAGATAAGGTACAC
    GTTAGTTTATCAGGAGAAGATGGCGGTATCAATTTATTTCCATTTGAAATATATGAGCCC
    CGCTTTGGAACTATTTTTGAAAGCAAAGCTAATGTTGAGCATAACGAAGACATTGCTGGT
    GAGAGACAGGCGCGTAACTTTGTCAATGCGTGTTTAGGTATAGAAGAGATTGTGGTGAAA
    CCGGAAGAAGCACGCAATGTAAATGCCCTTATAGAAGCGATTTATCGTAGCGATCTTGAT
    AACAAGAGCATACAACTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1041

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS01240 [old locus tag: SA0211 ]
  • symbol: SA_RS01240
  • description: gfo/Idh/MocA family oxidoreductase
  • length: 346
  • theoretical pI: 6.5723
  • theoretical MW: 38550
  • GRAVY: -0.168786

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Sugars inositol 2-dehydrogenase (TIGR04380; EC 1.1.1.18; HMM-score: 106.9)
  • TheSEED: see SA0211
  • PFAM:
    NADP_Rossmann (CL0063) GFO_IDH_MocA; Oxidoreductase family, NAD-binding Rossmann fold (PF01408; HMM-score: 105.3)
    and 4 more
    ox_reductase_C (CL0218) GFO_IDH_MocA_C; Oxidoreductase family, C-terminal alpha/beta domain (PF02894; HMM-score: 35.8)
    NADP_Rossmann (CL0063) NAD_binding_3; Homoserine dehydrogenase, NAD binding domain (PF03447; HMM-score: 21.9)
    CoA_binding; CoA binding domain (PF02629; HMM-score: 13.6)
    NAD_binding_7; Putative NAD(P)-binding (PF13241; HMM-score: 13.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006081
    • TAT(Tat/SPI): 0.000203
    • LIPO(Sec/SPII): 0.001069
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTKLKVGVIGVGGIAQDRHIPALLKLKDTVSLVAVQDINTVQMIDVAKRFNIPQAVETPSELFKLVDAVVICTPNKFHADLSIEALNHGVHVLCEKPMAMTTEECDRMIEAANKNHKLLTVAYHYRHTDVAMTAKKAIEAGVVGKPLVARVQAMRRRKVPGWGVFTNKALQGGGSLIDYGCHLLDLSLWLLGKDMVPHEVLGKTYNQLSKQPNQINDWGTFDHTKFDVDDHVTSYMTFANRASMQFECSWSANIKEDKVHVSLSGEDGGINLFPFEIYEPRFGTIFESKANVEHNEDIAGERQARNFVNACLGIEEIVVKPEEARNVNALIEAIYRSDLDNKSIQL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CcpA, MalR see SA0211

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://aureowiki.med.uni-greifswald.de/index.php?title=SA_RS01240&oldid=98232"