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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS04290 [old locus tag: SAS020 ]
  • pan locus tag?: SAUPAN002811000
  • symbol: SA_RS04290
  • pan gene symbol?:
  • synonym:
  • product: histidine phosphatase family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS04290 [old locus tag: SAS020 ]
  • symbol: SA_RS04290
  • product: histidine phosphatase family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 860392..860952
  • length: 561
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (860392..860952) NCBI
  • BioCyc: SA_RS04290 BioCyc
  • MicrobesOnline: see SAS020

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGCGCCACGGACAAACTTTGTTTAATTTTAAGGGACTAATTCAGGGATTTGGAGATTCG
    CCGCTAACAGAACTTGGAATTGCTCAAGCTCAAAAGGCACGTAGTTATTATGAAACTAAG
    GGGATAAACTTCGATTTATATGCATCATCAACGCAAGAACGCGCAAGTGACACACTTGAA
    AATGTTGCACCTAACCAATCGTATCAACGTTTTAAGGGACTGAAGGAATGGCATTTTGGA
    ATATTTGAAGGTGAGTCAGTCTATCTATTTGATAATCTATACAAGCCTGAGGACTTATTC
    GGAGATCGAATTGTTCCTTTCAAAGGAGAGGCAAGGCAACAAGTTGAAGAACGCATTGTG
    AAAACTTTACATGACATTATGTCTCAAACAAAGAATAATGCATTAGTCGTGAGTCATGGA
    ACAATAATGGGAGTATTTTTAAGATATTGCCTTAAACTAGATGAAGCATTAAAGCATAAT
    ATCGGTAATTGTAATATCCTGAAATTTGAATATGACAATGGAACATTTAAATTTGTTGAG
    TTAATTGATCCAAATTTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    561

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS04290 [old locus tag: SAS020 ]
  • symbol: SA_RS04290
  • description: histidine phosphatase family protein
  • length: 186
  • theoretical pI: 6.35683
  • theoretical MW: 21342
  • GRAVY: -0.413441

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin alpha-ribazole phosphatase (TIGR03162; EC 3.1.3.73; HMM-score: 65)
    and 2 more
    phosphoglycerate mutase 1 family (TIGR01258; HMM-score: 37.3)
    Signal transduction Regulatory functions Protein interactions phosphohistidine phosphatase SixA (TIGR00249; EC 3.1.3.-; HMM-score: 18.9)
  • TheSEED: see SAS020
  • PFAM:
    His_phosphatase (CL0071) His_Phos_1; Histidine phosphatase superfamily (branch 1) (PF00300; HMM-score: 120.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.049798
    • TAT(Tat/SPI): 0.011232
    • LIPO(Sec/SPII): 0.003719
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGIFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEERIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]