PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS07600 [old locus tag: SA1341 ]
• pan locus tag^?: SAUPAN004050000
• symbol: SA_RS07600
• pan gene symbol^?: spcT
• synonym:
• product: MFS transporter

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS07600 [old locus tag: SA1341 ]
• symbol: SA_RS07600
• product: MFS transporter
• replicon: chromosome
• strand: -
• coordinates: 1549029..1550246
• length: 1218
• essential: no DEG

⊟Accession numbers

• Location: NC_002745 (1549029..1550246) NCBI
• BioCyc: SA_RS07600 BioCyc
• MicrobesOnline: see SA1341

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  
  ATGTCATATACTTCTGTATTGTTTAATAAGAACTTTACTTTTTATTTAATAGGGATAGCT
  TTTTCTAACATGGGCAGTGCTTTTACTACGTTTGTTTTTCCATTAATGATTTTAAAGCTT
  ACTGGATCTGCATTTCAAGTTGGCATAGTTTCTGCACTAAGTTTTATACCTTATGCAATT
  TTAGGATTGCCAGCTGGTGCTTTAATTGACAGATTGAATAAGAAGACCATAATGAAATGT
  GCTGATATAATTAGGTTCGTTTCATATTTAAGTATACCAGTATTAAGTTTTTTCAATATG
  TTAAGCATCTTTCAAATTTATGTAGTTGCAATCATTTCAGGTATTGGATTAGTATTTCAC
  AGTATTTCTGAGGTTTCGATAATCCCAAGTATTGTAAAAGAAGAAGATTTGGCGAGCGCA
  AACAGTTATATATACGCTACTCAAAATGTTTCGGAATTTTTGGGCCCTATAATTGGAGGT
  TTACTTTATACATATATGGGATATTCAATATTGATTTTTATAGATTCTATGACTTTTTTA
  CTCTCATTTTTCAGTTTGATATTAATTAAAATTGAAACAAAGAGTATATTCAATCAAGAA
  AAGTTGAGTGGAAAAAATTTTTTGAGCGATGTTAAAGTTGGATTTGATTATCTATTATCT
  AATTCAACTATTAGAGTAATGGCTGTTGTTGTAAGTTTATCCAATCTAATTATCTCACCT
  TATTATATTTATATAGTAATGTTTGTAAAGGAAGACATGAATCAATCATCTCAAGCATTG
  GGGTTAGTTTTAGGTATCTCATCATTAGGTGCGCTAATCGGTTCATTATCTGCAAGTTTT
  CTCTTGAAATTATTTAATTTCGGAAAACTAATTGTAATTATATTATTTTTAGATACAATT
  TTTAGATTAATGTTACCATTTAGTACTTATATTTTTATACTCATCCCACTTTTAGGGTTG
  ACATATATGACACAATCCATTTTAAATATAGCGATAATCACACTGAGGCAAAAGAAATGT
  TCAGAAAATATGTTAGGACGTGTTAATAGTGTTTTTAAAACAATGGTTTTTGCATTCAGA
  CCTATAGGCCTTTTTTTAGGCGGTATATTACTTGAAAATAAAGGTGGATTTTATGCACTT
  ACGATCAGTGCTGTGTTATTTATACCATTAGTGTTATATATACTGAAAAATAGATTTTAT
  CAAGTTGAAGAATATTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  1020
  1080
  1140
  1200
  1218
  

⊟Protein

⊟General

• locus tag: SA_RS07600 [old locus tag: SA1341 ]
• symbol: SA_RS07600
• description: MFS transporter
• length: 405
• theoretical pI: 9.53556
• theoretical MW: 45126.7
• GRAVY: 0.928889

⊟Function

• TIGRFAM:
  Metabolism Transport and binding proteins Cations and iron carrying compounds H+ Antiporter protein (TIGR00900; HMM-score: 229.8)
  and 3 more
  multidrug resistance protein (TIGR00880; HMM-score: 40.2)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-galactonate transporter (TIGR00893; HMM-score: 22.5)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids phosphoglycerate transporter family protein (TIGR00881; HMM-score: 8.8)
• TheSEED: see SA1341
• PFAM:
  MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 105.6)
  MFS_3; Transmembrane secretion effector (PF05977; HMM-score: 88.9)
  and 1 more
  no clan defined GPHR_N; The Golgi pH Regulator (GPHR) Family N-terminal (PF12537; HMM-score: 8.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 10
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.011449
  • TAT(Tat/SPI): 0.000366
  • LIPO(Sec/SPII): 0.004593
• predicted transmembrane helices (TMHMM): 10

⊟Accession numbers

• GI: 446044855 NCBI
• RefSeq: WP_000122710 NCBI
• UniProt: see SA1341

⊟Protein sequence

• MSYTSVLFNKNFTFYLIGIAFSNMGSAFTTFVFPLMILKLTGSAFQVGIVSALSFIPYAILGLPAGALIDRLNKKTIMKCADIIRFVSYLSIPVLSFFNMLSIFQIYVVAIISGIGLVFHSISEVSIIPSIVKEEDLASANSYIYATQNVSEFLGPIIGGLLYTYMGYSILIFIDSMTFLLSFFSLILIKIETKSIFNQEKLSGKNFLSDVKVGFDYLLSNSTIRVMAVVVSLSNLIISPYYIYIVMFVKEDMNQSSQALGLVLGISSLGALIGSLSASFLLKLFNFGKLIVIILFLDTIFRLMLPFSTYIFILIPLLGLTYMTQSILNIAIITLRQKKCSENMLGRVNSVFKTMVFAFRPIGLFLGGILLENKGGFYALTISAVLFIPLVLYILKNRFYQVEEY

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications