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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS08385 [old locus tag: SA1490 ]
  • pan locus tag?: SAUPAN004278000
  • symbol: SA_RS08385
  • pan gene symbol?:
  • synonym:
  • product: aminopeptidase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS08385 [old locus tag: SA1490 ]
  • symbol: SA_RS08385
  • product: aminopeptidase
  • replicon: chromosome
  • strand: -
  • coordinates: 1697759..1698832
  • length: 1074
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (1697759..1698832) NCBI
  • BioCyc: SA_RS08385 BioCyc
  • MicrobesOnline: see SA1490

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGACAATGATATATAGAAATAATTTCATTGTGTTCGTTTTATCATTTTTTATTAGTATT
    ATATTGTATTCATCGCACGTATTACTCCCATTTATGTTTGGTCCTATTATCGCATCAATC
    ATTTGTGTGAAAGTTTTCAAACTTGATATTAAATGGCCATTCTTACTTAGTGAATTAGGG
    ATTGTACTATTAGGGGTGCAAATCGGATCAACGTTTACGAAAAATGTCGTTATGGATATT
    AAAAACAATTGGCTTTCGATTATTGTTGTATCTATTTCGATATTATTAATTGCAATAGTA
    ATGGCATTTATTTTTAAAAAAATTGCACGTATTAATACAGAAACAGCTATTTTAAGTGTT
    ATACCAGGAGCACTAACACAAATGCTGGTCATGGCTGAACAAGACAAACGTGCTAATTTG
    TTAGTTGTTAGCTTAACGCAAACATCACGAATTATATTTGTTGTTGTTTTAGTACCGTTC
    ATTTCATATTTTTTTCATGATGGTAACATGCATGCGAATGGAAAGTTAACAAAAGTCTTG
    CCTTTATCACAAGTATTAAACATAGGGCAAATAGTTATTTTAGCGATAGCTATCTTTATA
    GTTTATCTAATTATGTCTAAAATAAAGTTTCCAACATTTCAATTATTAGCACCACTCATT
    GTATTAATTGTTTGGAATTTTTCTACAGGTTTAACATTTACACTAGATCATTGGTTGTTG
    AACATGGCACAACTAATATATATGATTAGAATTGGAGTTCAAATTGCGCATTTATTGTCA
    GATTTAAAAGGTAGACTAGCAATCGCAATTACAATTCAAAATATTATGTTGATAATTGGT
    GCGCTAATCATGGTTTATATCATACATTTCTTTGATAATAATCCTATTAATGAATTGTTT
    CTTGGTGCAGCACCAGGAGGGGTTAATCAGATAGTTTTAGTTGCATTAGCTACTGGTGCC
    GATGTTGCTATGATTACGAGTTATCATATTTTCCGAATCTTTTTCATCCTATTTATTATT
    GCACCAGGAATTAATTACTTTTTAAAATATCGTTCGAATAAGCGTGAAGATTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1074

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS08385 [old locus tag: SA1490 ]
  • symbol: SA_RS08385
  • description: aminopeptidase
  • length: 357
  • theoretical pI: 10.1975
  • theoretical MW: 40109.5
  • GRAVY: 1.08375

Function[edit | edit source]

  • TIGRFAM:
    membrane protein AbrB duplication (TIGR03082; HMM-score: 238.2)
  • TheSEED: see SA1490
  • PFAM:
    Membrane_trans (CL0142) AbrB; Transition state regulatory protein AbrB (PF05145; HMM-score: 256.9)
    and 2 more
    CPA_AT (CL0064) Asp-Al_Ex; Predicted Permease Membrane Region (PF06826; HMM-score: 22.7)
    Actin_ATPase (CL0108) BcrAD_BadFG; BadF/BadG/BcrA/BcrD ATPase family (PF01869; HMM-score: 13.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006155
    • TAT(Tat/SPI): 0.000558
    • LIPO(Sec/SPII): 0.005272
  • predicted transmembrane helices (TMHMM): 10

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MTMIYRNNFIVFVLSFFISIILYSSHVLLPFMFGPIIASIICVKVFKLDIKWPFLLSELGIVLLGVQIGSTFTKNVVMDIKNNWLSIIVVSISILLIAIVMAFIFKKIARINTETAILSVIPGALTQMLVMAEQDKRANLLVVSLTQTSRIIFVVVLVPFISYFFHDGNMHANGKLTKVLPLSQVLNIGQIVILAIAIFIVYLIMSKIKFPTFQLLAPLIVLIVWNFSTGLTFTLDHWLLNMAQLIYMIRIGVQIAHLLSDLKGRLAIAITIQNIMLIIGALIMVYIIHFFDNNPINELFLGAAPGGVNQIVLVALATGADVAMITSYHIFRIFFILFIIAPGINYFLKYRSNKRED

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]