PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS09225 [old locus tag: SA1640 ]
• pan locus tag^?: SAUPAN004607000
• symbol: SA_RS09225
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS09225 [old locus tag: SA1640 ]
• symbol: SA_RS09225
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 1874153..1874647
• length: 495
• essential: no DEG

⊟Accession numbers

• Location: NC_002745 (1874153..1874647) NCBI
• BioCyc: SA_RS09225 BioCyc
• MicrobesOnline: see SA1640

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  
  ATGAGGAGATTACTCAGTCTATTACTAGCTAGTACAATGATTTTAGTCGCATGTGGGAAT
  GCTAACAATGAAAATAAGAAAAAGGAAGACGAAAAAAAATCAGAAGTAAAAAAAGAAGCT
  ACGAAAAATAATGATAAACCAAAGAACGAAAAGAAGAATCAAGATATAAATAAAAACAAT
  AATGAGCAAGTTCAAAATGTCAATAATAAACAACCAGTCTTAAATAATAATAGTAATCAT
  AACAATCAACAACAAAGCAATAAAAATAATTACACAGTTATAGAAAACGGGAATACAGTT
  ACAGAAATTTATAATGGACAATCACACACAACTACAAATAACCCTATTAGAGAAGAATAT
  GTAGAGGGAGAAACAGACCCGATATATAAAAGAGAGTATAAGCATTTTTATACACCTGAA
  GAAGCTCAAAGAGCACAAGAAAATAGCGACCAAATTTTAAGAGAAATGGGTCTCGAACCA
  GAAAGATATGAATAA
  60
  120
  180
  240
  300
  360
  420
  480
  495
  

⊟Protein

⊟General

• locus tag: SA_RS09225 [old locus tag: SA1640 ]
• symbol: SA_RS09225
• description: hypothetical protein
• length: 164
• theoretical pI: 6.29008
• theoretical MW: 19125.8
• GRAVY: -1.54939

⊟Function

• TIGRFAM:
  mycoides cluster lipoprotein, LppA/P72 family (TIGR03490; HMM-score: 16.9)
  Cellular processes Cellular processes Sporulation and germination sporulation lipoprotein, YhcN/YlaJ family (TIGR02898; HMM-score: 15.5)
  and 6 more
  Sec region non-globular protein (TIGR04420; HMM-score: 9.1)
  cobaltochelatase subunit (TIGR02442; EC 6.6.1.2; HMM-score: 8.1)
  Cellular processes Cellular processes Chemotaxis and motility flagellar biosynthesis protein FlhF (TIGR03499; HMM-score: 7.6)
  GLPGLI family protein (TIGR01200; HMM-score: 6.2)
  Metabolism Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 4.1)
  Cellular processes Cellular processes Sporulation and germination stage III sporulation protein AE (TIGR02829; HMM-score: 3.3)
• TheSEED: see SA1640
• PFAM:
  no clan defined FAM176; FAM176 family (PF14851; HMM-score: 12.6)
  AhpD-like (CL0423) PA26; PA26 p53-induced protein (sestrin) (PF04636; HMM-score: 11.7)
  LppaM (CL0421) LPAM_1; Prokaryotic membrane lipoprotein lipid attachment site (PF08139; HMM-score: 11.7)
  no clan defined TP53IP5; Cellular tumour antigen p53-inducible 5 (PF15331; HMM-score: 10.1)
  and 12 more
  DMT (CL0184) Zip; ZIP Zinc transporter (PF02535; HMM-score: 9.6)
  no clan defined DUF4638; Domain of unknown function (DUF4638) (PF15472; HMM-score: 9.5)
  Peptidase_AD (CL0130) Presenilin; Presenilin (PF01080; HMM-score: 9.3)
  no clan defined Serinc; Serine incorporator (Serinc) (PF03348; HMM-score: 8.9)
  Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region (PF02932; HMM-score: 8.6)
  NPR (CL0435) NPR3; Nitrogen Permease regulator of amino acid transport activity 3 (PF03666; HMM-score: 8.4)
  FUSC (CL0307) ALMT; Aluminium activated malate transporter (PF11744; HMM-score: 8.1)
  DMT (CL0184) CSG2; Ceramide synthase regulator (PF16965; HMM-score: 8.1)
  no clan defined WDCP; WD repeat and coiled-coil-containing protein family (PF15390; HMM-score: 7.7)
  GPCR_A (CL0192) SID-1_RNA_chan; dsRNA-gated channel SID-1 (PF13965; HMM-score: 7.6)
  no clan defined Spore_YhcN_YlaJ; Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) (PF09580; HMM-score: 6.5)
  CLN3; CLN3 protein (PF02487; HMM-score: 6.4)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 3.33
  • Cellwall Score: 3.33
  • Extracellular Score: 3.33
  • Internal Helix: 1
• LocateP:
• SignalP: Signal peptide LIPO(Sec/SPII) length 17 aa
  • SP(Sec/SPI): 0.000858
  • TAT(Tat/SPI): 0.000097
  • LIPO(Sec/SPII): 0.998715
  • Cleavage Site: CS pos: 17-18. LVA-CG. Pr: 0.9992
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 447176176 NCBI
• RefSeq: WP_001253432 NCBI
• UniProt: see SA1640

⊟Protein sequence

• MRRLLSLLLASTMILVACGNANNENKKKEDEKKSEVKKEATKNNDKPKNEKKNQDINKNNNEQVQNVNNKQPVLNNNSNHNNQQQSNKNNYTVIENGNTVTEIYNGQSHTTTNNPIREEYVEGETDPIYKREYKHFYTPEEAQRAQENSDQILREMGLEPERYE

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications