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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS09245 [old locus tag: SA1643 ]
  • pan locus tag?: SAUPAN004609000
  • symbol: SA_RS09245
  • pan gene symbol?: sen
  • synonym:
  • product: exotoxin

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS09245 [old locus tag: SA1643 ]
  • symbol: SA_RS09245
  • product: exotoxin
  • replicon: chromosome
  • strand: -
  • coordinates: 1877369..1878124
  • length: 756
  • essential: no DEG

Accession numbers[edit | edit source]

  • Location: NC_002745 (1877369..1878124) NCBI
  • BioCyc: SA_RS09245 BioCyc
  • MicrobesOnline: see SA1643

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGAGATTGTTCTACATAGCTGCAATTATAATAACTTTATTATGTCTTATTAATAATAAT
    TATGTTAATGCTGAAGTAGACAAAAAAGATTTAAAGAAAAAATCTGATCTAGATAGTAGT
    AAGTTATTTAATTTAACAAGCTATTATACTGATATAACGTGGCAATTAGACGAGTCAAAT
    AAAATTAGTACAGATCAACTACTGAATAATACTATAATATTAAAAAATATTGATATATCC
    GTACTTAAAACTTCTAGTTTGAAAGTTGAGTTTAACTCATCAGATTTAGCAAATCAATTT
    AAAGGAAAAAATATAGATATTTATGGACTGTATTTTGGAAATAAATGTGTAGGCTTAACT
    GAAGAAAAAACATCATGCTTATACGGAGGAGTTACGATACATGATGGAAATCAATTAGAT
    GAAGAGAAAGTTATAGGCGTTAATGTATTTAAAGATGGTGTCCAACAAGAAGGTTTTGTT
    ATAAAAACCAAAAAGGCTAAAGTAACAGTACAAGAATTAGACACTAAAGTTCGATTTAAA
    TTAGAAAATTTATATAAAATATACAATAAAGATACCGGTAACATACAAAAAGGATGCATT
    TTCTTTCATTCTCATAATCATCAAGATCAATCATTTTATTATGATTTATATAACGTAAAA
    GGTTCAGTGGGAGCAGAGTTTTTTCAATTTTATAGTGATAATAGAACAGTTAGCTCATCT
    AATTATCATATTGATGTATTTTTATATAAAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    756

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS09245 [old locus tag: SA1643 ]
  • symbol: SA_RS09245
  • description: exotoxin
  • length: 251
  • theoretical pI: 7.02705
  • theoretical MW: 28819.4
  • GRAVY: -0.354582

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SA1643
  • PFAM:
    Ant-toxin_C (CL0386) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 84.1)
    and 3 more
    OB_enterotoxin (CL0658) Stap_Strp_toxin; Staphylococcal/Streptococcal toxin, OB-fold domain (PF01123; HMM-score: 39)
    no clan defined DUF1413; Domain of unknown function (DUF1413) (PF07205; HMM-score: 12.6)
    BPD_transp_1 (CL0404) YjgP_YjgQ; Predicted permease YjgP/YjgQ family (PF03739; HMM-score: 12.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0
    • Extracellular Score: 10
    • Internal Helix: 1
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 24 aa
    • SP(Sec/SPI): 0.988593
    • TAT(Tat/SPI): 0.000317
    • LIPO(Sec/SPII): 0.002995
    • Cleavage Site: CS pos: 24-25. VNA-EV. Pr: 0.9722
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MRLFYIAAIIITLLCLINNNYVNAEVDKKDLKKKSDLDSSKLFNLTSYYTDITWQLDESNKISTDQLLNNTIILKNIDISVLKTSSLKVEFNSSDLANQFKGKNIDIYGLYFGNKCVGLTEEKTSCLYGGVTIHDGNQLDEEKVIGVNVFKDGVQQEGFVIKTKKAKVTVQELDTKVRFKLENLYKIYNKDTGNIQKGCIFFHSHNHQDQSFYYDLYNVKGSVGAEFFQFYSDNRTVSSSNYHIDVFLYKD

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]