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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS10125 [old locus tag: SA1761 ]
  • pan locus tag?: SAUPAN005038000
  • symbol: SA_RS10125
  • pan gene symbol?: sep
  • synonym:
  • product: exotoxin

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS10125 [old locus tag: SA1761 ]
  • symbol: SA_RS10125
  • product: exotoxin
  • replicon: chromosome
  • strand: -
  • coordinates: 2011380..2012162
  • length: 783
  • essential: no DEG

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2011380..2012162) NCBI
  • BioCyc: SA_RS10125 BioCyc
  • MicrobesOnline: see SA1761

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    GTGAGTAAAATAAAAAAAACAACATTTATACTACTTTCATTTATTGCCCTAACGTTGATA
    ACAAGTCCATTTGTAAATTGTAGCGAGAAAAGCGAAGAAATAAATGGAAAAGATTTACAA
    AAAAAGTCTGAATTGCAGGGAACTGCTTTAAGCAATCTTAGACAAACCTATTATCATAAT
    GGAAGTGCTATAATTGAAAATAAAGAGAGTAATGATCAATTTTTAAAGAACACTATATTG
    TTTAATGATTTTTTTACAGGTCATCAATGGTATAATGATTTATTAGTAGACCTTGGTTCA
    AAAGACACCGCCAATATATACAAAGGGAAAAAAGTGGATTTATATGGTGTTTATTATGGT
    TATCAATGTACTGGGGGTACACCATTCAAAACAGCTTGTATGTATGGCGGTGTAACGTTA
    CATGATAATAATCAATTGGAGGAAGAAAAGAAAGTACCGATTAACTTATGGATAGATGGT
    AAACAAAATACAGTACCTTTGGGAACGGTTAAAACTAATAAAAAAGAAGTAACTGTTCAG
    GAGCTAGACCTTCAGTCAAGACATTATTTACATGAAACATATAATTTATATAACACAGAT
    GCATTTAATGGAAAAATACAAAGAGGATTAATTGAGTTTCACCCTTCTTCTGGTGATTCG
    GTTGGTTATGATTTATTTGGTGCTCAAGGACAATATCCAGATACACAGTTGAGGATATAT
    AGAGATAATAAAACGATTAAGTCTAAAAATATGCATATTGATATATATTTATATACAACT
    TGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    783

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS10125 [old locus tag: SA1761 ]
  • symbol: SA_RS10125
  • description: exotoxin
  • length: 260
  • theoretical pI: 7.61272
  • theoretical MW: 29708.3
  • GRAVY: -0.578846

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SA1761
  • PFAM:
    Ant-toxin_C (CL0386) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 113.7)
    and 1 more
    OB_enterotoxin (CL0658) Stap_Strp_toxin; Staphylococcal/Streptococcal toxin, OB-fold domain (PF01123; HMM-score: 26.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0
    • Extracellular Score: 10
    • Internal Helix: 1
  • LocateP:
  • SignalP: Signal peptide LIPO(Sec/SPII) length 26 aa
    • SP(Sec/SPI): 0.494503
    • TAT(Tat/SPI): 0.001092
    • LIPO(Sec/SPII): 0.501455
    • Cleavage Site: CS pos: 26-27. FVN-CS. Pr: 0.4999
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSKIKKTTFILLSFIALTLITSPFVNCSEKSEEINGKDLQKKSELQGTALSNLRQTYYHNGSAIIENKESNDQFLKNTILFNDFFTGHQWYNDLLVDLGSKDTANIYKGKKVDLYGVYYGYQCTGGTPFKTACMYGGVTLHDNNQLEEEKKVPINLWIDGKQNTVPLGTVKTNKKEVTVQELDLQSRHYLHETYNLYNTDAFNGKIQRGLIEFHPSSGDSVGYDLFGAQGQYPDTQLRIYRDNKTIKSKNMHIDIYLYTT

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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