PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159JSNZLGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS10130 [old locus tag: SA1762 ]
• pan locus tag^?: SAUPAN005041000
• symbol: SA_RS10130
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS10130 [old locus tag: SA1762 ]
• symbol: SA_RS10130
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 2012574..2012948
• length: 375
• essential: no DEG

⊟Accession numbers

• Location: NC_002745 (2012574..2012948) NCBI
• BioCyc: SA_RS10130 BioCyc
• MicrobesOnline: see SA1762

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  
  TTGGATGATATTCAGAAAATAAAAAAAGAGCTTTCTGAATTAGTTGAACGTGTTGATGAT
  GTTGAAATACTAGCAAACGAAACAGCTGATCATGTGCTTGAACTTAGAGAGGAACATAAG
  CAACATCATAATGAACTAAGAGAATCTCATAAAGAACTTAAAGATAAGCAAGATAAAGTT
  GTAGATGAGAATTTAGAGCAAACAAAGATATTAAACAGAATTGAAGAAAGATATCAAACG
  CAAGTAGATGTTGCGCAAAAAAATGAAGAAAAGACACTCGCCCAAAATAAATGGCTCGTA
  GGTGCCATATGGGCGCTTGTAACAATTGTTATGATTGCAGTCATTACTGCATCAATTACT
  GCGTTATTACCTTAA
  60
  120
  180
  240
  300
  360
  375
  

⊟Protein

⊟General

• locus tag: SA_RS10130 [old locus tag: SA1762 ]
• symbol: SA_RS10130
• description: hypothetical protein
• length: 124
• theoretical pI: 4.77438
• theoretical MW: 14429.3
• GRAVY: -0.557258

⊟Function

• TIGRFAM:
  SH3 domain protein (TIGR04211; HMM-score: 17)
  and 5 more
  Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 12.5)
  Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 12.5)
  Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 9.9)
  Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 9.9)
  Genetic information processing Protein synthesis tRNA aminoacylation serine--tRNA ligase (TIGR00414; EC 6.1.1.11; HMM-score: 9)
• TheSEED: see SA1762
• PFAM:
  no clan defined DUF6674; Family of unknown function (DUF6674) (PF20379; HMM-score: 19.5)
  CheZ; Chemotaxis phosphatase, CheZ (PF04344; HMM-score: 16.9)
  PHA_synth_III_E; Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) (PF09712; HMM-score: 15.9)
  and 14 more
  Ion_channel (CL0030) Lig_chan; Ligand-gated ion channel (PF00060; HMM-score: 15.2)
  Flavoprotein (CL0042) Flavodoxin_3; Flavodoxin domain (PF12641; HMM-score: 14.7)
  no clan defined US6; Viral unique short region 6 (PF17616; HMM-score: 13.4)
  DUF6092; Family of unknown function (DUF6092) (PF19585; HMM-score: 13.4)
  TMPIT; TMPIT-like protein (PF07851; HMM-score: 12.7)
  DAG1; Dystroglycan (Dystrophin-associated glycoprotein 1) (PF05454; HMM-score: 12.6)
  DUF7603; Domain of unknown function (DUF7603) (PF24554; HMM-score: 11.8)
  TPR_MLP1_2; TPR/MLP1/MLP2-like protein (PF07926; HMM-score: 11.4)
  DUF334; Domain of unknown function (DUF334) (PF03904; HMM-score: 10.6)
  AATF-Che1; Apoptosis antagonizing transcription factor (PF13339; HMM-score: 10.4)
  PF (CL0431) AP-5_subunit_s1; AP-5 complex subunit sigma-1 (PF15001; HMM-score: 10.4)
  no clan defined zf-C4H2; Zinc finger-containing protein (PF10146; HMM-score: 9.4)
  DUF4337; Domain of unknown function (DUF4337) (PF14235; HMM-score: 9.4)
  Pec_lyase-like (CL0268) FapA; Flagellar Assembly Protein A beta solenoid domain (PF03961; HMM-score: 6.6)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helix: 1
• DeepLocPro: Cytoplasmic Membrane
  • Cytoplasmic Score: 0.008
  • Cytoplasmic Membrane Score: 0.8127
  • Cell wall & surface Score: 0.0249
  • Extracellular Score: 0.1545
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.001774
  • TAT(Tat/SPI): 0.001282
  • LIPO(Sec/SPII): 0.000299
• predicted transmembrane helices (TMHMM): 1

⊟Accession numbers

• GI: 446263122 NCBI
• RefSeq: WP_000340977 NCBI
• UniProt: see SA1762

⊟Protein sequence

• MDDIQKIKKELSELVERVDDVEILANETADHVLELREEHKQHHNELRESHKELKDKQDKVVDENLEQTKILNRIEERYQTQVDVAQKNEEKTLAQNKWLVGAIWALVTIVMIAVITASITALLP

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications