PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS10525 [old locus tag: SA1834 ]
• pan locus tag^?: SAUPAN005254000
• symbol: SA_RS10525
• pan gene symbol^?: —
• synonym:
• product: transcriptional regulator

⊟Additional information (user-provided)

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS10525 [old locus tag: SA1834 ]
• symbol: SA_RS10525
• product: transcriptional regulator
• replicon: chromosome
• strand: +
• coordinates: 2070412..2071086
• length: 675
• essential: no DEG

⊟Accession numbers

• Location: NC_002745 (2070412..2071086) NCBI
• BioCyc: SA_RS10525 BioCyc
• MicrobesOnline: see SA1834

⊟Phenotype

⊟Additional information (user-provided)

⊟DNA sequence

• 1
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  661
  
  ATGATTAGAAATAGATTGTCTGAACTACTGTCAGAAAGAGGACTAAAAATATCTCGTGTT
  GCAAAAGATGTAAAAATAGCAAGAAGTTCACTTACTTCAATGGCACAAAATGATTCTGAA
  ATGATAAGATATGATGCTATAGATAAATTATGTAGTTATCTGCACATATCTCCTTCAGAA
  TTTTTTGAACATAATCCGATCAATTTTGACTTTACTTTTGATGAAGAACCGAATTATAAA
  ATTAATGATGTTTTCGAGGGATTTGAAGTAACTGCAAACATTACTCACGCTTTTTCGATT
  GAAAATTTTGACTTTGAAATTTTAGTAGACGTCGAATTAGATAATAGGCAAAAATTAAAT
  TTTGACTTAGACGTCTCATATAAAGAAACTGAAAAGATAACTAATTCACAACATAGATTT
  ATTTTCACGATTAAAAATGAAGATGAAAATATCGGATTAAAAAAATACGTTGATAGTTTA
  TCTGCAGGCCTTAAAAACTTGTTATTTAAAAAAATTAACCAAAAGTTAAGTGGGTATGTT
  TCTGAAATAATAGTAAAAAATATAGACGATATTGAAGAGCTTTTTCCAAATAAAGGCGAA
  AAAAGTACGACTCTACATAAAGAAATTTTACAAACTGATAGCCGTTTATCTAGTGATATT
  TTTAAAGAATATTAA
  60
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  675
  

⊟Protein

⊟General

• locus tag: SA_RS10525 [old locus tag: SA1834 ]
• symbol: SA_RS10525
• description: transcriptional regulator
• length: 224
• theoretical pI: 4.76882
• theoretical MW: 26084.2
• GRAVY: -0.476786

⊟Function

• TIGRFAM:
• TheSEED: see SA1834
• PFAM:
  HTH (CL0123) HTH_26; Cro/C1-type HTH DNA-binding domain (PF13443; HMM-score: 48.2)
  and 3 more
  HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 22)
  HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 14.4)
  HTH_3; Helix-turn-helix (PF01381; HMM-score: 13.5)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.7124
  • Cytoplasmic Membrane Score: 0.1563
  • Cell wall & surface Score: 0.0049
  • Extracellular Score: 0.1264
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.009677
  • TAT(Tat/SPI): 0.006551
  • LIPO(Sec/SPII): 0.002198
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446543511 NCBI
• RefSeq: WP_000620857 NCBI
• UniProt: see SA1834

⊟Additional information (user-provided)

⊟Protein sequence

• MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Additional information (user-provided)

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Additional information (user-provided)

⊟Other information (user-provided)

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications