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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS10795 [old locus tag: SA1876 ]
  • pan locus tag?: SAUPAN005343000
  • symbol: SA_RS10795
  • pan gene symbol?:
  • synonym:
  • product: membrane protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS10795 [old locus tag: SA1876 ]
  • symbol: SA_RS10795
  • product: membrane protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2123363..2123854
  • length: 492
  • essential: no DEG other strains

Accession numbers[edit | edit source]

  • Location: NC_002745 (2123363..2123854) NCBI
  • BioCyc: SA_RS10795 BioCyc
  • MicrobesOnline: see SA1876

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAGGGATTATAATTTTATGTCACCACACGCTAAAAAAGTGATGAGGTTAAGTGCTGTG
    CTGTTTTGGATACCCATAGCGCTTGTACTTTTAATCGCATTTAATATTTTGAACTGGCTA
    TTTTGGGAGATATTAGATAACAATATATCCATTGTTAGTAGTGTGATTATAATATTACTT
    GTTGCTGTTTTCACGCTTGTCATAGCGCCAGTATATCGATATAAGCACTGCAGATATGCA
    TTTGAAAAACACCATTTGCGTGTACGAAACGGCATTTTATTTTTGGATGAAAAAGTAATA
    CCATATTTTCGTATTCAAAATATTGATATCGATGTTGGTCCTATAATGAGACGCTATCGA
    TTAGCAACTTTGACCCTTTATACAGCGGGTGGTCAAGCTGAAATTGAATTAATAGATAGA
    AGTGAAGCACGTAGATTGAAACGATGGTTAAATAACGAGAGACATTTAGAAAACAATAAA
    AATGAGGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    492

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA_RS10795 [old locus tag: SA1876 ]
  • symbol: SA_RS10795
  • description: membrane protein
  • length: 163
  • theoretical pI: 9.99458
  • theoretical MW: 19381.7
  • GRAVY: 0.13681

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: see SA1876
  • PFAM:
    PH (CL0266) bPH_2; Bacterial PH domain (PF03703; HMM-score: 69.8)
    and 7 more
    no clan defined DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 15.9)
    PH (CL0266) Rtt106; Histone chaperone Rttp106-like (PF08512; HMM-score: 15.3)
    bPH_3; Bacterial PH domain (PF14470; HMM-score: 12.8)
    no clan defined RseC_MucC; Positive regulator of sigma(E), RseC/MucC (PF04246; HMM-score: 12.3)
    DUF3974; Domain of unknown function (DUF3974) (PF13120; HMM-score: 12.3)
    YlaC; Inner membrane protein YlaC (PF10777; HMM-score: 10.1)
    DUF4191; Domain of unknown function (DUF4191) (PF13829; HMM-score: 6.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001133
    • TAT(Tat/SPI): 0.000167
    • LIPO(Sec/SPII): 0.014009
  • predicted transmembrane helices (TMHMM): 2

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MRDYNFMSPHAKKVMRLSAVLFWIPIALVLLIAFNILNWLFWEILDNNISIVSSVIIILLVAVFTLVIAPVYRYKHCRYAFEKHHLRVRNGILFLDEKVIPYFRIQNIDIDVGPIMRRYRLATLTLYTAGGQAEIELIDRSEARRLKRWLNNERHLENNKNEE

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]