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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

organism: Staphylococcus aureus N315
locus tag: SA_RS11665 [old locus tag: SA2028 ]
pan locus tag^?: SAUPAN005682000
symbol: SA_RS11665
pan gene symbol^?: secY
synonym:
product: protein translocase subunit SecY

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

type: CDS
locus tag: SA_RS11665 [old locus tag: SA2028 ]
symbol: SA_RS11665
product: protein translocase subunit SecY
replicon: chromosome
strand: -
coordinates: 2298151..2299443
length: 1293
essential: yes ^[1] DEG other strains

⊟Accession numbers[edit | edit source]

Location: NC_002745 (2298151..2299443) NCBI
BioCyc: SA_RS11665 BioCyc
MicrobesOnline: see SA2028

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

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1021
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ATGATTCAAACCCTTGTGAACTTCTTTAGAACAAAAGAGGTTCGTAACAAGATTTTCTTC
ACACTAGCAATGTTAGTAATTTTTAAAATAGGGACTTATATACCAGCTCCAGGAGTAAAT
CCTGCAGCTTTTGATAATCCCCAAGGTTCTCAAGGTGCCACTGAGTTATTAAATACTTTT
GGTGGCGGAGCCTTGAAACGATTTTCTATTTTTGCAATGGGTATTGTACCCTACATCACT
GCATCAATCGTAATGCAATTATTACAAATGGATATTGTCCCTAAATTCTCAGAATGGGCA
AAACAAGGTGAAGTAGGTAGAAGAAAGTTAAATAACGTTACTCGTTATTTAGCAATTTCT
TTAGCATTTATCCAATCTATAGGTATGGCATTCCAATTTAATAATTATCTCAAAGGTGCG
CTGATTATCAATCAGTCAATTATGAGTTATTTATTAATAGCACTAGTTTTGACAGCAGGA
ACTGCTTTCTTAATATGGCTTGGTGATCAAATCACTCAGTTCGGTGTTGGTAATGGTATT
TCTATTATCATATTTGCGGGTATTTTATCAACGTTGCCAGCCAGTCTAATTCAATTTGGA
CAAACTGCGTTCGTTGGGCAAGAAGATACATCATTAGCATGGTTGAAAGTATTAGGACTT
TTAGTGTCACTGATACTATTAACTGTAGGTGCTATTTATGTACTTGAAGCCGTTCGTAAA
ATTCCGATTCAATATGCTAAGAAACAAACTGCTCAAAGATTAGGTTCACAGGCAACTTAT
CTACCTTTAAAAGTGAACTCAGCCGGTGTTATTCCTGTAATCTTTGCAATGGCGTTCTTC
TTACTGCCTAGAACATTAACGTTGTTCTATCCAGATAAAGAATGGGCACAAAACATTGCG
AATGCTGCAAATCCTTCAAGTAATGTTGGTATGGTTGTATATATTGTACTAATTATACTA
TTCACATACTTCTATGCATTTGTACAAGTTAATCCGGAAAAAATGGCTGATAACCTTAAG
AAACAAGGTAGCTATGTTCCAGGCATTAGACCTGGTGAACAAACCAAAAAATATATTACT
AAAGTTTTATATCGTTTAACTTTTGTAGGTTCTATCTTCTTAGCCGTTATTTCAATTCTA
CCAATATTAGCAACTAAGTTTATGGGATTACCACAATCAATTCAGATTGGTGGTACAAGT
TTACTTATCGTTATTGGTGTAGCGATTGAAACAATGAAATCTTTAGAAGCTCAAGTATCT
CAAAAAGAATATAAAGGCTTTGGTGGTAGATAA
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⊟Protein[edit | edit source]

⊟General[edit | edit source]

locus tag: SA_RS11665 [old locus tag: SA2028 ]
symbol: SA_RS11665
description: protein translocase subunit SecY
length: 430
theoretical pI: 10.3709
theoretical MW: 47147.6
GRAVY: 0.554419

⊟Function[edit | edit source]

TIGRFAM:
Genetic information processing Protein fate Protein and peptide secretion and trafficking preprotein translocase, SecY subunit (TIGR00967; HMM-score: 482.9)
and 1 more
Genetic information processing Protein fate Protein and peptide secretion and trafficking accessory Sec system translocase SecY2 (TIGR02920; HMM-score: 209.7)
TheSEED: see SA2028
PFAM:
no clan defined SecY; SecY translocase (PF00344; HMM-score: 360.2)

⊟Structure, modifications & cofactors[edit | edit source]

domains:
modifications:
cofactors:
effectors:

⊟Localization[edit | edit source]

PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 9
LocateP:
SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.461739
- TAT(Tat/SPI): 0.011703
- LIPO(Sec/SPII): 0.015722
predicted transmembrane helices (TMHMM): 10

⊟Accession numbers[edit | edit source]

GI: 446539438 NCBI
RefSeq: WP_000616784 NCBI
UniProt: see SA2028

⊟Protein sequence[edit | edit source]

MIQTLVNFFRTKEVRNKIFFTLAMLVIFKIGTYIPAPGVNPAAFDNPQGSQGATELLNTFGGGALKRFSIFAMGIVPYITASIVMQLLQMDIVPKFSEWAKQGEVGRRKLNNVTRYLAISLAFIQSIGMAFQFNNYLKGALIINQSIMSYLLIALVLTAGTAFLIWLGDQITQFGVGNGISIIIFAGILSTLPASLIQFGQTAFVGQEDTSLAWLKVLGLLVSLILLTVGAIYVLEAVRKIPIQYAKKQTAQRLGSQATYLPLKVNSAGVIPVIFAMAFFLLPRTLTLFYPDKEWAQNIANAANPSSNVGMVVYIVLIILFTYFYAFVQVNPEKMADNLKKQGSYVPGIRPGEQTKKYITKVLYRLTFVGSIFLAVISILPILATKFMGLPQSIQIGGTSLLIVIGVAIETMKSLEAQVSQKEYKGFGGR

⊟Experimental data[edit | edit source]

experimentally validated: data available for COL, NCTC8325
protein localization: data available for COL
quantitative data / protein copy number per cell:
interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

regulator:

⊟Transcription pattern[edit | edit source]

S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Aureolib: no data available

⊟Protein stability[edit | edit source]

half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

↑ R Allyn Forsyth, Robert J Haselbeck, Kari L Ohlsen, Robert T Yamamoto, Howard Xu, John D Trawick, Daniel Wall, Liangsu Wang, Vickie Brown-Driver, Jamie M Froelich, Kedar G C, Paula King, Melissa McCarthy, Cheryl Malone, Brian Misiner, David Robbins, Zehui Tan, Zhan-yang Zhu Zy, Grant Carr, Deborah A Mosca, Carlos Zamudio, J Gordon Foulkes, Judith W Zyskind
A genome-wide strategy for the identification of essential genes in Staphylococcus aureus.
Mol Microbiol: 2002, 43(6);1387-400
[PubMed:11952893] [WorldCat.org] [DOI] (P p)

⊟Relevant publications[edit | edit source]

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