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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS12900 [old locus tag: SA2246 ]
  • pan locus tag?: SAUPAN006014000
  • symbol: SA_RS12900
  • pan gene symbol?: —
  • synonym:
  • product: prevent-host-death protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS12900 [old locus tag: SA2246 ]
  • symbol: SA_RS12900
  • product: prevent-host-death protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2522760..2523017
  • length: 258
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2522760..2523017) NCBI
  • BioCyc: SA_RS12900 BioCyc
  • MicrobesOnline: see SA2246

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTT
    AATAATAATCACGAACCAATTTATATTAGTGGCAATAATGCCGAAAATAATGCTGTGATT
    ATAGGTTTAGAAGATTGGAAAAGTATACAAGAGACAATATATCTTGAATCTACTGGTACA
    ATGGACAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
    GATTGGGATAATCTTTAA
    60
    120
    180
    240
    258

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS12900 [old locus tag: SA2246 ]
  • symbol: SA_RS12900
  • description: prevent-host-death protein
  • length: 85
  • theoretical pI: 4.1354
  • theoretical MW: 9774.67
  • GRAVY: -0.805882

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Toxin production and resistance prevent-host-death family protein (TIGR01552; HMM-score: 37.9)
    Genetic information processing Mobile and extrachromosomal element functions Other prevent-host-death family protein (TIGR01552; HMM-score: 37.9)
    and 1 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (TIGR00420; EC 2.1.1.61; HMM-score: 11.4)
  • TheSEED: see SA2246
  • PFAM:
    Plasmid-antitox (CL0136) PhdYeFM_antitox; Antitoxin Phd_YefM, type II toxin-antitoxin system (PF02604; HMM-score: 62.8)
    and 1 more
    PHD_like; Antitoxin of toxin-antitoxin, RelE / RelB, TA system (PF12910; HMM-score: 21.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006313
    • TAT(Tat/SPI): 0.000113
    • LIPO(Sec/SPII): 0.000337
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIITSPTEARKDFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKSIQETIYLESTGTMDKVREREKDNSGTTNIDDIDWDNL

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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