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NCBI: 02-MAR-2017

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS13135 [old locus tag: SA2291 ]
  • pan locus tag?: SAUPAN006098000
  • symbol: SA_RS13135
  • pan gene symbol?: fnbA
  • synonym:
  • product: fibronectin-binding protein A

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SA_RS13135 [old locus tag: SA2291 ]
  • symbol: SA_RS13135
  • product: fibronectin-binding protein A
  • replicon: chromosome
  • strand: -
  • coordinates: 2571889..2575005
  • length: 3117
  • essential: no DEG other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_002745 (2571889..2575005) NCBI
  • BioCyc: SA_RS13135 BioCyc
  • MicrobesOnline: see SA2291

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    GTGAAAAACAATCTTAGGTACGGCATTAGAAAACATAAATTGGGAGCAGCATCAGTATTC
    TTAGGAACAATGATCGTTGTTGGGATGGGACAAGATAAAGAAGCTGCAGCATCAGAACAA
    AAGACAACTACAGTAGAAGAAAATGGGAATTCAGCTACTGATAATAAAACAAGTGAAACA
    CAAACAACTGCTACTAACGTTAATCATATAGAAGAAACTCAATCATATAACGCAACAGTA
    ACAGAACAACCGTCAAACGCAACACAAGTAACAACTGAAGAAGCACCAAAAGCAGTACAA
    GCACCACAAACTGCACAACCAGCAAATGTAGAAACAGTTAAAGAAGAAGAGAAACCTCAA
    GTTAAGGAAACGACACAACCTCAAGACAATAGCGGAAATCAAAGACAAGTAGATTTAACA
    CCTAAAAAGGTTACACAAAATCAAGGGACAGAAACACAAGTTGAAGTGGCACAGCCAAGA
    ACGGCATCAGAAAGTAAGCCACGTGTGACAAGATCAGCAGATGTAGCGGAAGCTAAGGAA
    GCTAGTGACGTTTCAGAAGTTAAAGGCACAGATGTTACAAGTAAAGTTACAGTAGAAAGT
    GGTTCTATTGAGGCACCTCAAGGAAATAAAGTAGAGCCACATGCTGGTCAACGTGTCGTA
    TTGAAATACAAATTGAAATTCGCAGATGGATTAAAAAGAGGAGATTATTTTGATTTTACA
    TTATCAAATAATGTAAATACTTATGGGGTTTCAACAGCTAGAAAGGTACCAGAGATTAAA
    AATGGCTCAGTTGTAATGGCTACAGGTGAGATCTTAGGGAATGGTAACATAAGATATACA
    TTTACTAACGAAATTGAACACAAGGTAGAGGTAACAGCTAATTTAGAAATCAACTTATTT
    ATTGACCCTAAAACTGTACAAAGCAATGGAGAACAAAAGATTACTTCTAAATTAAATGGT
    GAAGAAACAGAAAAAACAATACCAGTTGTTTATAATCCAGGTGTTAGCAATAGTTATACA
    AATGTAAATGGATCAATTGAAACATTTAATAAAGAATCTAATAAATTTACACATATAGCT
    TATATTAAGCCAATGAATGGAAACCAGTCAAACACTGTATCAGTAACAGGGACGTTGACT
    GAAGGTAGTAATTTAGCTGGTGGACAACCTACTGTTAAAGTATATGAATATCTAGGGAAA
    AAAGATGAATTGCCACAAAGTGTTTATGCAAATACATCAGATACTAACAAATTCAAAGAT
    GTAACAAAGGAAATGAATGGAAAATTGAGTGTGCAAGACAATGGTAGTTACTCATTGAAT
    TTAGATAAGTTGGATAAAACGTATGTCATTCATTATACAGGTGAATATTTGCAAGGGTCA
    GATCAGGTTAATTTTAGAACTGAATTATATGGGTATCCAGAACGAGCATATAAATCTTAC
    TATGTTTATGGGGGATATCGTTTAACTTGGGATAATGGTTTAGTTTTATATAGCAATAAA
    GCTGACGGCAATGGTAAAAATGGACAAATTATTCAAGATAATGATTTTGAATATAAAGAA
    GATACTGCAAAAGGAACTATGAGCGGGCAGTACGATGCCAAGCAAATTATTGAAACAGAA
    GAAAATCAAGACAATACACCGCTTGACATTGATTACCACACAGCTATAGATGGTGAGGGT
    GGTTATGTTGATGGGTATATTGAAACAATAGAAGAAACGGATTCATCAGCTATTGATATC
    GATTACCATACTGCTGTGGATAGTGAAGTGGGTCACGTTGGAGGATACACTGAGTCCTCT
    GAGGAATCAAATCCAATTGACTTTGAAGAATCGACACATGAAAATTCAAAACATCACGCT
    GATGTTGTTGAATATGAAGAGGATACAAATCCAGGTGGTGGCCAAGTAACAACTGAGTCT
    AACTTAGTTGAATTTGACGAAGAGTCTACAAAAGGTATTGTAACTGGCGCAGTGAGCGAC
    CATACAACAATTGAAGATACGAAAGAATATACGACTGAAAGTAATCTGATTGAACTAGTA
    GATGAACTACCTGAAGAACATGGTCAAGCACAAGGACCAATCGAGGAAATTACTGAAAAC
    AATCATCATATTTCTCATTCTGGTTTAGGAACTGAAAATGGTCACGGTAATTATGGCGTG
    ATTGAAGAAATCGAAGAAAATAGCCACGTTGATATTAAGAGTGAATTAGGTTACGAAGGT
    GGCCAAAATAGCGGTAACCAGTCATTCGAGGAAGACACAGAAGAAGACAAACCTAAATAT
    GAACAAGGTGGCAATATCGTAGATATCGATTTCGACAGTGTACCTCAAATTCATGGTCAA
    AATAAAGGTGACCAGTCATTCGAAGAAGATACAGAGAAAGACAAGCCTAAATATGAACAT
    GGCGGTAATATCATTGATATCGACTTCGACAGTGTGCCACAAATTCATGGATTCAATAAG
    CATAATGAAATTATTGAAGAAGATACAAACAAAGATAAACCTAATTATCAATTCGGTGGA
    CACAATAGTGTTGACTTTGAAGAAGATACACTTCCAAAAGTAAGCGGCCAAAATGAAGGT
    CAACAAACGATTGAAGAAGATACAACGCCGCCAACGCCACCGACACCAGAAGTACCGAGT
    GAGCCGGAAACACCAATGCCACCGACACCAGAAGTACCGAGTGAGCCGGAAACACCAACG
    CCACCAACACCAGAGGTACCAAGTGAGCCGGAAACACCAACACCACCGACTCCGGAAGTA
    CCAAGTGAGCCGGAAACACCAACACCACCGACACCAGAAGTGCCGAGTGAGCCAGAAACA
    CCAACACCGCCAACACCAGAGGTACCAGCTGAACCTGGTAAACCAGTACCACCCGCAAAA
    GAAGAACCTAAAAAGCCTTCTAAACCAGTGGAACAAGGTAAAGTAGTAACACCTGTTATT
    GAAATCAATGAAAAGGTTAAAGCAGTGGCACCAACTAAAAAAGCACAATCTAAGAAATCT
    GAACTACCTGAAACAGGTGGAGAAGAATCAACAAACAAAGGTATGTTGTTCGGCGGATTA
    TTCAGCATTCTAGGTTTAGCATTATTACGCAGAAATAAAAAGAATAACAAAGCATAA
    60
    120
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    240
    300
    360
    420
    480
    540
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    2160
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    2700
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    2820
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    3000
    3060
    3117

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SA_RS13135 [old locus tag: SA2291 ]
  • symbol: SA_RS13135
  • description: fibronectin-binding protein A
  • length: 1038
  • theoretical pI: 4.26899
  • theoretical MW: 113618
  • GRAVY: -0.943545

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 25.1)
    gram-positive signal peptide, YSIRK family (TIGR01168; HMM-score: 21.9)
  • TheSEED: see SA2291
  • PFAM:
    Adhesin (CL0204) SdrG_C_C; C-terminus of bacterial fibrinogen-binding adhesin (PF10425; HMM-score: 115.7)
    no clan defined Fn_bind; Fibronectin binding repeat (PF02986; HMM-score: 104.5)
    and 2 more
    Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 33)
    YSIRK_signal; YSIRK type signal peptide (PF04650; HMM-score: 32.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 0
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 37 aa
    • SP(Sec/SPI): 0.882163
    • TAT(Tat/SPI): 0.008947
    • LIPO(Sec/SPII): 0.090988
    • Cleavage Site: CS pos: 37-38. AAA-SE. Pr: 0.7401
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKNNLRYGIRKHKLGAASVFLGTMIVVGMGQDKEAAASEQKTTTVEENGNSATDNKTSETQTTATNVNHIEETQSYNATVTEQPSNATQVTTEEAPKAVQAPQTAQPANVETVKEEEKPQVKETTQPQDNSGNQRQVDLTPKKVTQNQGTETQVEVAQPRTASESKPRVTRSADVAEAKEASDVSEVKGTDVTSKVTVESGSIEAPQGNKVEPHAGQRVVLKYKLKFADGLKRGDYFDFTLSNNVNTYGVSTARKVPEIKNGSVVMATGEILGNGNIRYTFTNEIEHKVEVTANLEINLFIDPKTVQSNGEQKITSKLNGEETEKTIPVVYNPGVSNSYTNVNGSIETFNKESNKFTHIAYIKPMNGNQSNTVSVTGTLTEGSNLAGGQPTVKVYEYLGKKDELPQSVYANTSDTNKFKDVTKEMNGKLSVQDNGSYSLNLDKLDKTYVIHYTGEYLQGSDQVNFRTELYGYPERAYKSYYVYGGYRLTWDNGLVLYSNKADGNGKNGQIIQDNDFEYKEDTAKGTMSGQYDAKQIIETEENQDNTPLDIDYHTAIDGEGGYVDGYIETIEETDSSAIDIDYHTAVDSEVGHVGGYTESSEESNPIDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEESTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQNKGDQSFEEDTEKDKPKYEHGGNIIDIDFDSVPQIHGFNKHNEIIEEDTNKDKPNYQFGGHNSVDFEEDTLPKVSGQNEGQQTIEEDTTPPTPPTPEVPSEPETPMPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPAEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKKAQSKKSELPETGGEESTNKGMLFGGLFSILGLALLRRNKKNNKA

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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