PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA_RS13980 [old locus tag: SA2439 ]
• pan locus tag^?: SAUPAN006379000
• symbol: SA_RS13980
• pan gene symbol^?: sasF
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA_RS13980 [old locus tag: SA2439 ]
• symbol: SA_RS13980
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 2742448..2744355
• length: 1908
• essential: no DEG other strains

⊟Accession numbers

• Location: NC_002745 (2742448..2744355) NCBI
• BioCyc: SA_RS13980 BioCyc
• MicrobesOnline: see SA2439

⊟Phenotype

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⊟DNA sequence

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  ATGGCTAAATATCGAGGGAAACCGTTTCAATTATATGTAAAGTTATCGTGTTCGACAATG
  ATGGCGTCAAGTATCATTTTAACGAATATCTTGCCGTACGATGCCCAAGCTGCATCTGAA
  AAGGATACTGAAATTTCAAAAGAGATATTATCTAAGCAAGATTTATTAGACAAAGTTGAC
  AAAGCAATTCGTCAAATTGAGCAATTAAAACAGTTATCGGCTTCATCTAAAGCACATTAT
  AAAGCACAACTAAATGAAGCGAAAACAGCATCGCAAATAGATGAAATCATAAAACGAGCT
  AATGAGTTGGATAGCAAAGAAAATAAAAGTTCTCACACTGAAATGAACGGTCAAAGTGAT
  ATAGACAGTAAATTAGATCAATTGCTTAAAGATTTAAATGAGGTTTCTTCAAATGTTGAT
  AGGGGTCAACAAAGTGGCGAGGACGATCTTAATGCAATGAAAAATGATATGTCACAAACG
  GCTACAACAAAATATGGAGAAAAAGATGATAAAAATGATGAAGCAATGGTAAATAAGGCG
  TTAGAAGACCTAGACCATTTGAATCAGCAAATACACAAATCGAAAGATGCATTGAAAGAT
  GCATCGAAAGATCCGGCAGTGTCTACAACAGATAGTAATCATGAAGTAGCTAAAACGCCA
  AATAATGATGGTTCTGGACATGTTGTGTTAAATAAATTTCTTTCAAATGAAGAGAATCAA
  AGCCATAGTAATCAACTCACTGATAAATTACAAGGAAGCGATAAAATTAATCATGCTATG
  ATTGAAAAATTGGCTAAAAGTAATGCCTCAACGCAACATTACACATATCATAAACTGAAT
  ACGTTACAATCTTTAGATCAACGTATTGCAAATACGCAACTTCCTAAAAATCAAAAATCA
  GACTTAATGAGCGAAGTAAATAAGACGAAAGAGCGTATAAAAAGTCAACGAAATATTATT
  TTGGAAGAACTTGCACGTACTGATGATAAAAAGTATGCTACACAAAGCATTTTAGAAAGT
  ATATTTAATAAAGACGAGGCAGATAAAATTCTAAAAGATATACGTGTTGATGGTAAAACA
  GATCAACAAATTGCAGATCAAATTACTCGTCATATTGATCAACTATCTCTGACAACGAGT
  GATGATTTATTAACGTCATTGATTGATCAATCACAAGATAAGTCGCTATTGATTTCTCAA
  ATCTTACAAACGAAATTAGGAAAAGCTGAAGCAGATAAATTGGCTAAAGATTGGACGAAT
  AAAGGATTATCAAATCGCCAAATCGTTGACCAATTGAAGAAACATTTTGCATCAACTGGC
  GACACGTCTTCAGATGATATATTAAAAGCAATTTTGAATAATGCCAAAGATAAAAAGCAA
  GCAATTGAAACGATTTTAGCAACACGTATAGAAAGACAAAAGGCAAAATTACTGGCAGAT
  TTAATTACTAAAATAGAAACAGATCAAAATAAAATTTTTAATTTAGTTAAATCGGCATTG
  AATGGTAAAGCGGATGATTTATTGAATTTACAAAAGAGACTCAATCAAACGAAAAAAGAT
  ATAGACTATATTTTATCACCAATAGTAAATCGTCCAAGTTTACTAGATCGATTGAATAAA
  AATGGGAAAACAACGGATTTAAATAAGTTAGCAAATTTAATGAATCAAGGATCAAATTTA
  TTAGACAGTATTCCAGATATACCCACACCAAAGCCAGAAAAGACGTTAACACTTGGTAAA
  GGTAATGGATTGTTAAGTGGATTATTAAATGCTGATGGTAATGTATCTTTGCCTAAAGCG
  GGGGAAACGATAAAAGAACATTGGTTGCCGATATCTGTAATTGTTGGTGCAATGGGTGTA
  CTAATGATTTGGTTATCACGACGCAATAAGTTGAAAAATAAAGCATAA
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⊟Protein

⊟General

• locus tag: SA_RS13980 [old locus tag: SA2439 ]
• symbol: SA_RS13980
• description: hypothetical protein
• length: 635
• theoretical pI: 8.94127
• theoretical MW: 70840.6
• GRAVY: -0.734173

⊟Function

• TIGRFAM:
• TheSEED: see SA2439
• PFAM:
  HHH (CL0198) HHH_6; Helix-hairpin-helix motif (PF14579; HMM-score: 15.7)
  B_GA (CL0598) GA; GA module (PF01468; HMM-score: 15)
  no clan defined Poly_export; Polysaccharide biosynthesis/export protein (PF02563; HMM-score: 12.9)
  and 2 more
  SAP30_Sin3_bdg; Sin3 binding region of histone deacetylase complex subunit SAP30 (PF13867; HMM-score: 11.8)
  B2; RNA binding protein B2 (PF11473; HMM-score: 7.7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cellwall
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 0
  • Cellwall Score: 10
  • Extracellular Score: 0
  • Internal Helix: 1
• LocateP:
• SignalP: Signal peptide SP(Sec/SPI) length 37 aa
  • SP(Sec/SPI): 0.924285
  • TAT(Tat/SPI): 0.018817
  • LIPO(Sec/SPII): 0.004269
  • Cleavage Site: CS pos: 37-38. AQA-AS. Pr: 0.8814
• predicted transmembrane helices (TMHMM): 1

⊟Accession numbers

• GI: 447074634 NCBI
• RefSeq: WP_001151890 NCBI
• UniProt: see SA2439

⊟Protein sequence

• MAKYRGKPFQLYVKLSCSTMMASSIILTNILPYDAQAASEKDTEISKEILSKQDLLDKVDKAIRQIEQLKQLSASSKAHYKAQLNEAKTASQIDEIIKRANELDSKENKSSHTEMNGQSDIDSKLDQLLKDLNEVSSNVDRGQQSGEDDLNAMKNDMSQTATTKYGEKDDKNDEAMVNKALEDLDHLNQQIHKSKDALKDASKDPAVSTTDSNHEVAKTPNNDGSGHVVLNKFLSNEENQSHSNQLTDKLQGSDKINHAMIEKLAKSNASTQHYTYHKLNTLQSLDQRIANTQLPKNQKSDLMSEVNKTKERIKSQRNIILEELARTDDKKYATQSILESIFNKDEADKILKDIRVDGKTDQQIADQITRHIDQLSLTTSDDLLTSLIDQSQDKSLLISQILQTKLGKAEADKLAKDWTNKGLSNRQIVDQLKKHFASTGDTSSDDILKAILNNAKDKKQAIETILATRIERQKAKLLADLITKIETDQNKIFNLVKSALNGKADDLLNLQKRLNQTKKDIDYILSPIVNRPSLLDRLNKNGKTTDLNKLANLMNQGSNLLDSIPDIPTPKPEKTLTLGKGNGLLSGLLNADGNVSLPKAGETIKEHWLPISVIVGAMGVLMIWLSRRNKLKNKA

⊟Experimental data

• experimentally validated: data available for NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications