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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0193 [new locus tag: SA_RS01145 ]
  • pan locus tag?: SAUPAN001048000
  • symbol: SA0193
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA0193 [new locus tag: SA_RS01145 ]
  • symbol: SA0193
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 227874..229052
  • length: 1179
  • essential: no DEG

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAGGAAAGTTTTAAATATTTTTACAATAGCTTTTAAATCAATATTGAAAAATAAAGGT
    AGAAATATATTTACAATGATAGGTATAATCATCGGTATTTCTTCTGTTATTACGATAATG
    TCTTTGGGAAATGGCTTTAAAAAAACTGCTGCTGATCAATTTTCAGATGCTGGCGCCGGA
    AAACAAGAAGCGTTGATTAGCTTTACTTTTAAAGTTGATGAGAAAATCAAAAAGTATCCT
    TTTAATCAAAGAGATATAGAGTTGGTAAATCAAGTTGATGGCGTACTAGATGCGAAGCTA
    AAGGAAAATAAAGAAGAAGGAATTGAAGCCACAATAACTAATGTCCAGAAAAAAAGTGAC
    ATCTTCATTATAAAAAAACAAAATTTACACTCTTTTAAAGTAGGTAGAGGGTTTGATAAA
    GAGGATAATGAATTACGTAAGAAAATAGTGGTTATAAATGATCAAGTAGCAAAAACTGTA
    TTCAATAATAATGCTATTGGTAAATCGCTATATATTGAGGGACAGGGATTTGAAGTCATA
    GGAATTACGGATAAACTATATTCTGACTCATCTACCGTTATAATGCCTGAAAATACATTC
    AACTACTATATGGGACACTTACATCAAGGTCTGCCTACCTTACAGATAATTATTGAAGAT
    GGTTACAATAAAAAAACTGTAGTTAAAAAAGTAGAATCACTATTAAATAAAAAAGGATCG
    GGCTCTGTTTTAGGTGAGTATACATATACAGACACTGAAGAAATTATCAAAAGTATTGAT
    AAAATTTTTGATAGTATTACTTATTTTGTAGCAGCTGTTGCCGGTATTTCACTTTTTATT
    GCTGGTATTGGAGTTATGAATGTCATGTATATATCTGTAGCTGAAAGAACAGAAGAAATT
    GCGATACGACGTGCATTTGGTGCAAAAAGTCGAGATATTGAACTACAATTTTTAATAGAG
    AGCATTTTAATATGTGTGACAAGTGGTTTTATTGGACTTATTTTAGGTGTTGTGTTTGCA
    ACAATAATTGATGTATTAACACCAGATTATATTAAAAGTGTAGTAAGTTTGAGTTCTGTC
    ATAATTGCGGTTAGTGTGTCGATATTAATTGGACTTCTTTTTGGATGGATACCAGCTCGC
    GCAGCATCTAAGAAAGAGCTCATAGATATTATAAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1179

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA0193 [new locus tag: SA_RS01145 ]
  • symbol: SA0193
  • description: hypothetical protein
  • length: 392
  • theoretical pI: 9.39443
  • theoretical MW: 43335.3
  • GRAVY: 0.225765

Function[edit | edit source]

  • TIGRFAM:
    acidobacterial duplicated orphan permease (TIGR03434; HMM-score: 100)
    and 4 more
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein, LolC/E family (TIGR02212; HMM-score: 40)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein LolE (TIGR02213; HMM-score: 18.8)
    Cellular processes Cellular processes Cell division putative protein insertion permease FtsX (TIGR00439; HMM-score: 8.4)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking putative protein insertion permease FtsX (TIGR00439; HMM-score: 8.4)
  • TheSEED  :
    • ABC transporter, permease protein SERP0016
    MRSA analysis Oli  ABC transporter, permease protein
  • PFAM:
    no clan defined MacB_PCD; MacB-like periplasmic core domain (PF12704; HMM-score: 82.2)
    and 3 more
    BPD_transp_1 (CL0404) FtsX; FtsX-like permease family (PF02687; HMM-score: 51.2)
    no clan defined SpecificRecomb; Site-specific recombinase (PF10136; HMM-score: 10.7)
    Tetraspannin (CL0347) DUF4064; Protein of unknown function (DUF4064) (PF13273; HMM-score: 9.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 9.99
    • Cellwall Score: 0.01
    • Extracellular Score: 0.01
    • Internal Helices: 4
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -0.5
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.168094
    • TAT(Tat/SPI): 0.001081
    • LIPO(Sec/SPII): 0.016825
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MRKVLNIFTIAFKSILKNKGRNIFTMIGIIIGISSVITIMSLGNGFKKTAADQFSDAGAGKQEALISFTFKVDEKIKKYPFNQRDIELVNQVDGVLDAKLKENKEEGIEATITNVQKKSDIFIIKKQNLHSFKVGRGFDKEDNELRKKIVVINDQVAKTVFNNNAIGKSLYIEGQGFEVIGITDKLYSDSSTVIMPENTFNYYMGHLHQGLPTLQIIIEDGYNKKTVVKKVESLLNKKGSGSVLGEYTYTDTEEIIKSIDKIFDSITYFVAAVAGISLFIAGIGVMNVMYISVAERTEEIAIRRAFGAKSRDIELQFLIESILICVTSGFIGLILGVVFATIIDVLTPDYIKSVVSLSSVIIAVSVSILIGLLFGWIPARAASKKELIDIIK

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]