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PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 10-JUN-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0885 [new locus tag: SACOL_RS04545 ]
  • pan locus tag?: SAUPAN002841000
  • symbol: SACOL0885
  • pan gene symbol?: int
  • synonym:
  • product: pathogenicity island protein, integrase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SACOL0885 [new locus tag: SACOL_RS04545 ]
  • symbol: SACOL0885
  • product: pathogenicity island protein, integrase
  • replicon: chromosome
  • strand: -
  • coordinates: 903491..904711
  • length: 1221
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGTGGTTAGAAAAATTTAAAAATAAGAATAAAGAAACTAAATATAGATATTACGAGAAG
    TACAAAGACCCTCTCACTGCCAAATGGAGACGTGTTAGCGTGGTACTTAATAAGAATGGT
    AAGCAATCACAAAAAGAAGCTCAAAGACTCTTAAATGAGCGTATAGAAGCAAAACTGAAT
    GATAAGACACCTACTACACTTAAGTCACTAACTTTCCATGTCGCATGTGATGAGTGGTTT
    CAGAGTTATATCAAAACGTCTGGGTCAAAAAGAACAACTATTAAAACTAAATTGAGTAAG
    CTAAACACTTTGAAGAAATTTGTAGATGAAGATATTTTAATCAATAAAATAACACTTTCA
    TATGCGCAACAAGTTTTCGATGAAATGGATAATAAAGGTTATGTATATCAAGTAAACAAA
    GATGCGTTAAGCATATTCAAAAATGTATTTGAATACACTAGACGTATCTATAAACTGCAA
    GATTTAGAATTTTTAAAAGATATAACGTTAAATAAAAGAATTAAGTCTTATGATGAAGTG
    AAAGCTAAACGTAATAAGTACCTCGAATTAAATGAAATACAATCTATCATCAAAGATATT
    AATACGAAGGCTCAGAAGATGCACTCAGGTATCCATAAGCGGTTTTATTTATTCGTTGCA
    CTCATGACAGAATTCCAAGCCTTAAATGGTATGCGTATTGGTGAAATGTTAGCCATTCAA
    AATGAAGATATAGACTTTGATAATAAGAGTTTAAATATTAACGGAACAATCCATTGGTTT
    CACGATGAATCTGGTGGATTCGGTGTAAAAGATACCACTAAAACAGAGTCTAGTTATAGA
    ACAATTGGATTGAGTAGCAGAAGTTGCGAGATATTAAAGAAAGCAATACTGGAGAACAAA
    AAGGATTCAAAATGGAATGATGGATATCTAAATAGAAATTTTGTATTTACTAATCATAAA
    GGCAACCCAATGCAGACTGAAAGATTCAATAAAATCCTTAGGGAAGCAGCTAAAGATGTT
    GGTATTGATAAAGAAGTTTCTTCACATATATTAAGACATAGCCACATATCATTACTCTCT
    CAACAAGGCGTGTCACTTAAAGCTATTATGGATCGTGTAGGCCATTCCGACCACCGTACA
    ACACTTTCCATTTATTCTCACGTTACTGAACAGATGGATAAGGATATGATGAACAAACTT
    GAACAGGTAAAACTTGGATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1221

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SACOL0885 [new locus tag: SACOL_RS04545 ]
  • symbol: SACOL0885
  • description: pathogenicity island protein, integrase
  • length: 406
  • theoretical pI: 10.1504
  • theoretical MW: 47586.3
  • GRAVY: -0.724384

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerD (TIGR02225; HMM-score: 79.1)
    and 3 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerC (TIGR02224; HMM-score: 58.8)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair integron integrase (TIGR02249; HMM-score: 58.7)
    Genetic information processing Mobile and extrachromosomal element functions Other integron integrase (TIGR02249; HMM-score: 58.7)
  • TheSEED  :
    • Integrase, superantigen-encoding pathogenicity islands SaPI
    Phages, Prophages, Transposable elements, Plasmids Pathogenicity islands Staphylococcal pathogenicity islands SaPI  Integrase, superantigen-encoding pathogenicity islands SaPI
  • PFAM:
    DNA-mend (CL0382) Phage_integrase; Phage integrase family (PF00589; HMM-score: 105.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011643
    • TAT(Tat/SPI): 0.000629
    • LIPO(Sec/SPII): 0.004835
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MWLEKFKNKNKETKYRYYEKYKDPLTAKWRRVSVVLNKNGKQSQKEAQRLLNERIEAKLNDKTPTTLKSLTFHVACDEWFQSYIKTSGSKRTTIKTKLSKLNTLKKFVDEDILINKITLSYAQQVFDEMDNKGYVYQVNKDALSIFKNVFEYTRRIYKLQDLEFLKDITLNKRIKSYDEVKAKRNKYLELNEIQSIIKDINTKAQKMHSGIHKRFYLFVALMTEFQALNGMRIGEMLAIQNEDIDFDNKSLNINGTIHWFHDESGGFGVKDTTKTESSYRTIGLSSRSCEILKKAILENKKDSKWNDGYLNRNFVFTNHKGNPMQTERFNKILREAAKDVGIDKEVSSHILRHSHISLLSQQGVSLKAIMDRVGHSDHRTTLSIYSHVTEQMDKDMMNKLEQVKLG

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]