PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

⊟Summary

• pan ID^?: SAUPAN004583000
• symbol^?: lukD
• synonym:
• description^?: leucotoxin LukDv

  descriptions from strain specific annotations:

  • leucotoxin LukDv
  • leukotoxin LukD
  • beta-channel forming cytolysin
  • leukocidin D-subunit
  • leukocidin LukD precursor
  • leukotoxin, LukD
  • gamma-hemolysin component B
  • gamma-hemolysin component B precursor
  • leukocidin-F subunit (Gamma-hemolysin, H-gamma-I subunit)
  • leukotoxin D subunit
  • leukotoxin F-subunit
  • lukF-PV
• strand^?: -
• coordinates^?: 4816411..4829614
• synteny block^?: BlockID0035640
• occurrence^?: in 70% of 33 strains

⊟Orthologs

COL:
SACOL1880 (lukD)
N315:
SA1637 (lukD)
NCTC8325:
SAOUHSC_01954
Newman:
NWMN_1718 (lukD)
USA300_FPR3757:
SAUSA300_1768 (lukD)
04-02981:
SA2981_1774 (lukD)
08BA02176:
—
11819-97:
MS7_1824
6850:
RSAU_001674 (lukD)
71193:
—
ECT-R 2:
ECTR2_1652
ED133:
SAOV_1812 (lukD)
ED98:
SAAV_1828 (lukD)
HO 5096 0412:
—
JH1:
SaurJH1_1904
JH9:
SaurJH9_1870
JKD6008:
—
JKD6159:
—
LGA251:
SARLGA251_17080 (hlgB)
M013:
—
MRSA252:
—
MSHR1132:
—
MSSA476:
SAS1748 (hlgB)
Mu3:
SAHV_1804 (lukD)
Mu50:
SAV1819 (lukD)
MW2:
MW1767 (lukD)
RF122:
SAB1686c (lukD)
ST398:
—
T0131:
SAT0131_01946
TCH60:
—
TW20:
SATW20_18210 (hlgB)
USA300_TCH1516:
USA300HOU_1817 (lukD)
VC40:
SAVC_08360

⊟Genome Viewer

COL
N315
NCTC8325
Newman
USA300_FPR3757

⊟Alignments

• alignment of orthologues:
  CLUSTAL format alignment by MAFFT L-INS-i (v7.307)
  
  
  COL             MKMKKLVKSSVASSIALLLLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDNDKLNISQ
  N315            MKMKKLVKSSVASSIALLLLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDNDKLNISQ
  NCTC8325        MKMKKLVKSSVASSIALLLLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDNDKLNISQ
  Newman          MKMKKLVKSSVASSIALLLLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDNDKLNISQ
  USA300_FPR3757  MKMKKLVKSSVASSIALLLLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDNDKLNISQ
                  ************************************************************
  
  COL             ILTFNFIKDKSYDKDTLVLKAAGNINSGYKKPNPKDYNYSQFYWGGKYNVSVSSESNDAV
  N315            ILTFNFIKDKSYDKDTLVLKAAGNINSGYKKPNPKDYNYSQFYWGGKYNVSVSSESNDAV
  NCTC8325        ILTFNFIKDKSYDKDTLVLKAAGNINSGYKKPNPKDYNYSQFYWGGKYNVSVSSESNDAV
  Newman          ILTFNFIKDKSYDKDTLVLKAAGNINSGYKKPNPKDYNYSQFYWGGKYNVSVSSESNDAV
  USA300_FPR3757  ILTFNFIKDKSYDKDTLVLKAAGNINSGYKKPNPKDYNYSQFYWGGKYNVSVSSESNDAV
                  ************************************************************
  
  COL             NVVDYAPKNQNEEFQVQQTLGYSYGGDINISNGLSGGLNGSKSFSETINYKQESYRTTID
  N315            NVVDYAPKNQNEEFQVQQTLGYSYGGDINISNGLSGGLNGSKSFSETINYKQESYRTTID
  NCTC8325        NVVDYAPKNQNEEFQVQQTLGYSYGGDINISNGLSGGLNGSKSFSETINYKQESYRTTID
  Newman          NVVDYAPKNQNEEFQVQQTLGYSYGGDINISNGLSGGLNGSKSFSETINYKQESYRTTID
  USA300_FPR3757  NVVDYAPKNQNEEFQVQQTLGYSYGGDINISNGLSGGLNGSKSFSETINYKQESYRTTID
                  ************************************************************
  
  COL             RKTNHKSIGWGVEAHKIMNNGWGPYGRDSYDPTYGNELFLGGRQSSSNAGQNFLPTHQMP
  N315            RKTNHKSIGWGVEAHKIMNNGWGPYGRDSYDPTYGNELFLGGRQSSSNAGQNFLPTHQMP
  NCTC8325        RKTNHKSIGWGVEAHKIMNNGWGPYGRDSYDPTYGNELFLGGRQSSSNAGQNFLPTHQMP
  Newman          RKTNHKSIGWGVEAHKIMNNGWGPYGRDSYDPTYGNELFLGGRQSSSNAGQNFLPTHQMP
  USA300_FPR3757  RKTNHKSIGWGVEAHKIMNNGWGPYGRDSYDPTYGNELFLGGRQSSSNAGQNFLPTHQMP
                  ************************************************************
  
  COL             LLARGNFNPEFISVLSHKQNDTKKSKIKVTYQREMDRYTNQWNRLHWVGNNYKNQNTVTF
  N315            LLARGNFNPEFISVLSHKQNDTKKSKIKVTYQREMDRYTNQWNRLHWIGNNYKNQNTVTF
  NCTC8325        LLARGNFNPEFISVLSHKQNDTKKSKIKVTYQREMDRYTNQWNRLHWVGNNYKNQNTVTF
  Newman          LLARGNFNPEFISVLSHKQNDTKKSKIKVTYQREMDRYTNQWNRLHWVGNNYKNQNTVTF
  USA300_FPR3757  LLARGNFNPEFISVLSHKQNDTKKSKIKVTYQREMDRYTNQWNRLHWVGNNYKNQNTVTF
                  ***********************************************:************
  
  COL             TSTYEVDWQNHTVKLIGTDSKETNPGV
  N315            TSTYEVDWQNHTVKLIGTDSKETNPGV
  NCTC8325        TSTYEVDWQNHTVKLIGTDSKETNPGV
  Newman          TSTYEVDWQNHTVKLIGTDSKETNPGV
  USA300_FPR3757  TSTYEVDWQNHTVKLIGTDSKETNPGV
                  ***************************