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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS01500 [old locus tag: SAUSA300_0280 ]
  • pan locus tag?: SAUPAN001177000
  • symbol: SAUSA300_RS01500
  • pan gene symbol?: essA
  • synonym:
  • product: protein EssA

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_RS01500 [old locus tag: SAUSA300_0280 ]
  • symbol: SAUSA300_RS01500
  • product: protein EssA
  • replicon: chromosome
  • strand: +
  • coordinates: 333927..334385
  • length: 459
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGTTGATGAATAGCGTGATTGCTTTAACTTTTTTAACAGCATCTAGCAATAATGGCGGA
    CTTAATATTGATGTGCAACAAGAAGAGGAAAAGCGAATCAATAATGATTTAAATCAATAT
    GATACAACGCTATTTAATAAAGACAGCAAAGCGGTTAATGATGCGATTGCTAAGCAGAAA
    AAAGAACGACAACAACAAATAAAAAATGATATGTTTCAAAATCAAGCGAGTCACTCGACT
    CGCTTGAATGAAACTAAAAAAGTGTTATTTTCCAAATCTAACTTAGAAAAGACTTCGGAG
    AGTGATAAAAGCCCCTATATTCAAAACAAGCAGGAGAAAAAAATATTCCCGTACATTTTG
    ATGTCTGTAGGGGCTTTTTTGACTTTAGGATTTGTCATTTTTTCAATTCATAAAGGGAGA
    CGAACGAAAAATGAATCAGCACGTAAAAGTAACATTTGA
    60
    120
    180
    240
    300
    360
    420
    459

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_RS01500 [old locus tag: SAUSA300_0280 ]
  • symbol: SAUSA300_RS01500
  • description: protein EssA
  • length: 152
  • theoretical pI: 10.3846
  • theoretical MW: 17392.6
  • GRAVY: -0.768421

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EssA (TIGR03927; HMM-score: 113.3)
  • TheSEED: see SAUSA300_0280
  • PFAM:
    no clan defined EssA; WXG100 protein secretion system (Wss), protein EssA (PF10661; HMM-score: 27.4)
    and 5 more
    DUF2370; Protein of unknown function (DUF2370) (PF10176; HMM-score: 16.4)
    DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 16.1)
    YrhC; YrhC-like protein (PF14143; HMM-score: 14.5)
    PIRT; Phosphoinositide-interacting protein family (PF15099; HMM-score: 12.6)
    Peptidase_AD (CL0130) Presenilin; Presenilin (PF01080; HMM-score: 9.6)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.095756
    • TAT(Tat/SPI): 0.001748
    • LIPO(Sec/SPII): 0.319717
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MLMNSVIALTFLTASSNNGGLNIDVQQEEEKRINNDLNQYDTTLFNKDSKAVNDAIAKQKKERQQQIKNDMFQNQASHSTRLNETKKVLFSKSNLEKTSESDKSPYIQNKQEKKIFPYILMSVGAFLTLGFVIFSIHKGRRTKNESARKSNI

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]