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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_0408 [new locus tag: NWMN_RS02305 ]
  • pan locus tag?: SAUPAN002139000
  • symbol: lpl5nm
  • pan gene symbol?: lpl5
  • synonym:
  • product: tandem lipoprotein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_0408 [new locus tag: NWMN_RS02305 ]
  • symbol: lpl5nm
  • product: tandem lipoprotein
  • replicon: chromosome
  • strand: +
  • coordinates: 457321..458112
  • length: 792
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGGAATATCTAAAAAGGCTTGCATTGTTAATAAGTGTTATTATTTTGACCATTTTTATA
    ATGGGTTGTGATAGTCAAAGCGATACTGCAGAAAATCCAAAAGAAGGTTCAAAAGAAGCA
    CAAATTAAAAAGAGTTTTTCGAAAACGTTAGATATGTATCCAATTAAGAATCTCGAGGAT
    TTTTATGACAAAGAAGGATATCGAGATGGCGAATTTAAAAAAGATGATAAAGGTACTTGG
    CTAATTAGATCCGAAATAGTTAAACAGCCAAAGGGCAAAGTGATGAAAACAAGAGGTATG
    CAATTATATATTAATAGAAATACCGAAACAGCCAAAGGTTTCTTTGTTTTGAAAGAAATA
    AGTGAAAATAATAATCGTGTAAATAAAGATAAGGAGGAAAAATACGAAGTGAAAATGGTA
    GGAAATAAAATTATTCCTACTGAACAAATTAATGACGAGAAAATAAAAAAAGAAATTGAA
    AACTTCAAGTTTTTTGTGCAATATGGAAACTTTAAAAATTTCGAAAAATACAACAATGGT
    GAGTTTTCATATAATCCTGAAGCACCAATTTATTCGGCTAAATATCAATTACACAACGAT
    GATTACAATGTAAGGCAACTACGTAAAAGATATGACATTTCAACAAAAGAAACACCGAAG
    TTACTTTTGAAAGGTGGAGGAGATTTAAAAAATTCCTCAGTTGGTCAAAACGATATTGAA
    TTTACTTTTGTTGAAAGAAAAGGTGAGAATATTTATTTTAACGATAGTGTTGAATTCATA
    CCAAGTAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    792

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_0408 [new locus tag: NWMN_RS02305 ]
  • symbol: Lpl5nm
  • description: tandem lipoprotein
  • length: 263
  • theoretical pI: 9.1857
  • theoretical MW: 30819.8
  • GRAVY: -0.862738

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Staphylococcus tandem lipoproteins (TIGR01742; HMM-score: 343.3)
  • TheSEED:  
    FIG01107840: hypothetical protein 
  • PFAM:
    LolA_LolB (CL0048) DUF576; Csa1 family (PF04507; HMM-score: 383.3)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 4.6
    • Cellwall Score: 2.48
    • Extracellular Score: 2.92
    • Internal Helix: 1
  • LocateP: Lipid anchored
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPII)
    • Intracellular Possibility: 0
    • Signal Peptide Possibility: 0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: IFIMGCD
  • SignalP: Signal peptide length 28 aa
    • Ymax: 0.651
    • Ymax_pos: 28
    • Cmax: 0.547
    • Cmax_pos: 28
    • Smax: 0.941
    • Smax_pos: 22
    • Smean: 0.581
    • D: 0.624
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MEYLKRLALLISVIILTIFIMGCDSQSDTAENPKEGSKEAQIKKSFSKTLDMYPIKNLEDFYDKEGYRDGEFKKDDKGTWLIRSEIVKQPKGKVMKTRGMQLYINRNTETAKGFFVLKEISENNNRVNKDKEEKYEVKMVGNKIIPTEQINDEKIKKEIENFKFFVQYGNFKNFEKYNNGEFSYNPEAPIYSAKYQLHNDDYNVRQLRKRYDISTKETPKLLLKGGGDLKNSSVGQNDIEFTFVERKGENIYFNDSVEFIPSK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator: SaeR
    SaeR (TF) important in Virulence

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]