NCBI: 06-JUL-2013

⊟Summary

• organism: Staphylococcus aureus Newman
• locus tag: NWMN_0804 [new locus tag: NWMN_RS04550 ]
• pan locus tag^?: SAUPAN003032000
• symbol: dltB
• pan gene symbol^?: dltB
• synonym:
• product: D-alanine lipoteichoic acid and wall teichoic acid esterification protein

⊟Gene

⊟General

• type: CDS
• locus tag: NWMN_0804 [new locus tag: NWMN_RS04550 ]
• symbol: dltB
• product: D-alanine lipoteichoic acid and wall teichoic acid esterification protein
• replicon: chromosome
• strand: +
• coordinates: 892519..893733
• length: 1215
• essential: unknown other strains

⊟Accession numbers

• Gene ID: 5331863 NCBI
• RefSeq: YP_001331838 NCBI
• BioCyc:
• MicrobesOnline: 3706353 MicrobesOnline

⊟Phenotype

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⊟DNA sequence

• 1
  61
  121
  181
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  301
  361
  421
  481
  541
  601
  661
  721
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  841
  901
  961
  1021
  1081
  1141
  1201
  
  ATGATTCCATATGGTGATTTTACATTCTTCTTAATTGCTTTAATTGCATTATTACCAGTC
  ATTATACTTGGATTTTTAGGTAAGCGAAGTTACATTTATAATGGCGTAGTTACAGCATTT
  ATGATTGTGTTAATCTTTTCTTCTGATAAACATAATCTGTTTGACCAAAAGTATTTAAGT
  GTTCAATTAATTAGTTTTATTATTTACGTCGTATGGCAAGTTTTATTGATAATGTTTTAT
  TATCATTCAAAACCAAAAAATAATTCATTTTCAAAATTTGTAACTGTAATGGTTTTATCA
  ATATTGCCATTAGCACTTGTGAAAGTGTTACAAAGTACATGGTTAGGTGGACATCAGATT
  CACTTCCATGAAAGTAAATTAATTGAATTTGTTGGTTTCTTAGGAATTTCTTATGTTACA
  TTCAAAAGTGTGCAGTTAATTATGGAAATTCGTGATGGTTCTATCAAAGAAATTAAAGTA
  TGGAAATTAATTCAATTTATTTCATTCTTCCCAACGATTTCATCTGGACCAATCGATCGT
  TACAAACGTTTCGTTAAAGACGATAAAAAAGTACCAACAGGCAATGAATATCGTGAATTA
  GTATTAAAAGCAATTCACATGATTATGCTTGGTTTCTTGTATAAATATATTGTTGCTTAC
  TTTATTAACACATATGCAATCATGCCGTTACAATTAGACTTACATGGCTTTGTCAATTTG
  TGGTTATATATGTACGCATACAGCTTATATTTATTCTTTGACTTTGCAGGTTATAGTTTA
  TTTGCGATAGCATTTAGTTATTTATTCGGTATTAAAACACCACCAAACTTCGATAAACCT
  TTCAAAGCGAAAAATATTAAAGATTTCTGGAATAGATGGCATATGACATTATCATTCTGG
  TTCAGAGATTGTATTTACATGAGATCTTTATTCTACATGTCTCGTAAAAAATTATTGAAG
  AGTCAATTTGCAATGTCTAACGTGGCATTCTTAATCAACTTCTTCATAATGGGAATTTGG
  CATGGTATCGAAGTGTATTACATTGTTTATGGTTTATACCATGCAGCATTGTTTATAGGT
  TATGGCTATTATGAACGTTGGCGTAAGAAACATCCGCCACGTTGGCAAAATGGTTTCACA
  ACAGCACTTAGCATTGTGATTACATTCCACTTTGTAACATTTGGCTTTTTAATCTTCTCA
  GGTAAACTTATATAA
  60
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  1215
  

⊟Protein

⊟General

• locus tag: NWMN_0804 [new locus tag: NWMN_RS04550 ]
• symbol: DltB
• description: D-alanine lipoteichoic acid and wall teichoic acid esterification protein
• length: 404
• theoretical pI: 10.088
• theoretical MW: 47774.5
• GRAVY: 0.493812

⊟Function

• TIGRFAM:
  Cell structureCell envelopeBiosynthesis and degradation of murein sacculus and peptidoglycanD-alanyl-lipoteichoic acid biosynthesis protein DltB (TIGR04091; HMM-score: 522.2)
• TheSEED:  
  Cell Wall and CapsuleGram-Positive cell wall componentsD-Alanyl Lipoteichoic Acid Biosynthesis D-alanyl transfer protein DltB 
  and 1 more
  Gram-Positive cell wall componentsTeichoic and lipoteichoic acids biosynthesis D-alanyl transfer protein DltB 
• PFAM:
  MBOAT-like (CL0517) MBOAT; MBOAT, membrane-bound O-acyltransferase family (PF03062; HMM-score: 72.9)
  and 1 more
  MBOAT_2; Membrane bound O-acyl transferase family (PF13813; HMM-score: 31)

⊟Structure, modifications & interactions

• domains:
• modifications:
• cofactors:
• effectors:
• protein partners:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 9
• LocateP: Multi-transmembrane
  • Prediction by SwissProt Classification: Membrane
  • Pathway Prediction: Sec-(SPI)
  • Intracellular Possibility: 0.17
  • Signal Peptide Possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • Ymax: 0.101
  • Ymax_pos: 11
  • Cmax: 0.124
  • Cmax_pos: 42
  • Smax: 0.144
  • Smax_pos: 3
  • Smean: 0.101
  • D: 0.101
• predicted transmembrane helices (TMHMM): 10

⊟Accession numbers

• GI: 151221016 NCBI
• RefSeq: YP_001331838 NCBI
• UniProt: A0A0H3KFB2 UniProt

⊟Protein sequence

• MIPYGDFTFFLIALIALLPVIILGFLGKRSYIYNGVVTAFMIVLIFSSDKHNLFDQKYLSVQLISFIIYVVWQVLLIMFYYHSKPKNNSFSKFVTVMVLSILPLALVKVLQSTWLGGHQIHFHESKLIEFVGFLGISYVTFKSVQLIMEIRDGSIKEIKVWKLIQFISFFPTISSGPIDRYKRFVKDDKKVPTGNEYRELVLKAIHMIMLGFLYKYIVAYFINTYAIMPLQLDLHGFVNLWLYMYAYSLYLFFDFAGYSLFAIAFSYLFGIKTPPNFDKPFKAKNIKDFWNRWHMTLSFWFRDCIYMRSLFYMSRKKLLKSQFAMSNVAFLINFFIMGIWHGIEVYYIVYGLYHAALFIGYGYYERWRKKHPPRWQNGFTTALSIVITFHFVTFGFLIFSGKLI

⊟Experimental data

• experimentally validated: no data available

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: NWMN_0802 > dltA > dltB > dltC > dltD

⊟Regulation

• sigma factor:
• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Other Information

You are kindly invited to share additional interesting facts.