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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1075 [new locus tag: NWMN_RS06095 ]
  • pan locus tag?: SAUPAN003426000
  • symbol: NWMN_1075
  • pan gene symbol?: ssl12
  • synonym:
  • product: superantigen-like protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_1075 [new locus tag: NWMN_RS06095 ]
  • symbol: NWMN_1075
  • product: superantigen-like protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1178781..1179497
  • length: 717
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGAGTAAGAACATCACGAAAAATATAATTTTAACGACAACATTATTACTATTAGGTACT
    GTATTACCTCAAAATCAAAAACCAGTATTTAGTTTTTACTCTGAAGCTAAAGCTTATAGC
    ATTGGTCAAGATGAAACTAACATCAATGAATTAATTAAATATTACACACAGCCTCATTTT
    TCATTTTCAAATAAATGGCTATATCAATATGATAATGGAAACATTTATGTTGAACTTAAG
    AGATATTCATGGTCAGCACATATATCTTTATGGGGCGCTGAAAGTTGGGGAAATATTAAT
    CAGTTAAAAGATCGTTACGTAGATGTGTTTGGACTAAAAGACAAAGATACTGATCAGTTA
    TGGTGGTCTTATAGAGAGACATTTACAGGTGGCGTTACACCAGCCGCAAAACCTTCTGAT
    AAAACTTATAATCTTTTTGTGCAATACAAAGATAAACTACAAACGATTATTGGTGCGCAT
    AAAATATACCAAGGCAATAAACCAGTATTAACATTGAAAGAAATCGATTTCCGTGCACGA
    GAAGCGTTAATAAAAAATAAAATATTATATAACGAAAATCGTAATAAAGGTAAGCTTAAG
    ATCACCGGTGGCGGTAATAACTACACTATTGATTTAAGCAAAAGATTACATTCAGATCTA
    GCAAATGTTTATGTTAAAAATCCTAATAAAATAACTGTTGACGTCCTCTTTGATTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    717

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_1075 [new locus tag: NWMN_RS06095 ]
  • symbol: NWMN_1075
  • description: superantigen-like protein
  • length: 238
  • theoretical pI: 9.83237
  • theoretical MW: 27568.1
  • GRAVY: -0.542857

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:  
    FIG01107944: hypothetical protein 
  • PFAM:
    Ant-toxin_C (CL0386) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 21)
    OB_enterotoxin (CL0658) SSL_OB; Staphylococcal superantigen-like OB-fold domain (PF09199; HMM-score: 17.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.01
    • Extracellular Score: 9.97
    • Internal Helices: 0
  • LocateP: N-terminally anchored (No CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: -0.17
    • Signal Peptide Possibility: 1
    • N-terminally Anchored Score: 5
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.274
    • Ymax_pos: 27
    • Cmax: 0.17
    • Cmax_pos: 39
    • Smax: 0.766
    • Smax_pos: 9
    • Smean: 0.59
    • D: 0.397
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MSKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]

Ilse Jongerius, Jörg Köhl, Manoj K Pandey, Maartje Ruyken, Kok P M van Kessel, Jos A G van Strijp, Suzan H M Rooijakkers
Staphylococcal complement evasion by various convertase-blocking molecules.
J. Exp. Med.: 2007, 204(10);2461-71
[PubMed:17893203] [WorldCat.org] [DOI] (P p)