From AureoWiki
Jump to: navigation, search
NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_1079 [new locus tag: NWMN_RS06115 ]
  • pan locus tag?: SAUPAN003430000
  • symbol: arcC
  • pan gene symbol?: arcC1
  • synonym:
  • product: carbamate kinase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_1079 [new locus tag: NWMN_RS06115 ]
  • symbol: arcC
  • product: carbamate kinase
  • replicon: chromosome
  • strand: +
  • coordinates: 1182612..1183544
  • length: 933
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGCGAAAATAGTAGTAGCATTAGGTGGTAATGCTTTAGGAAAATCACCTCAAGAACAA
    CTCGAGCTTGTTAAAAATACTGCGAAATCATTAGTAGGATTAATAACAAAAGGACATGAG
    ATTGTTATTAGTCATGGTAATGGACCACAGGTTGGAAGCATTAATTTGGGACTTAACTAT
    GCTGCAGAACATAACCAAGGTCCGGCATTTCCATTTGCTGAATGTGGCGCAATGAGTCAA
    GCTTACATCGGCTATCAATTACAAGAAAGCTTACAAAATGAATTGCATTCTATTGGAATG
    GATAAACAAGTGGTAACACTAGTGACACAAGTTGAAGTTGATGAAAATGATCCGGCATTT
    AACAATCCTTCAAAACCAATTGGGTTATTTTACAACAAAGAAGAAGCTGAACAAATTCAA
    AAAGAAAAAGGATTTATATTTGTTGAAGATGCTGGAAGAGGATATAGACGCGTTGTTCCT
    TCACCACAACCCATCTCTATTATTGAATTAGAGAGTATTAAAACACTTATTAAAAATGAT
    ACACTCGTTATTGCTGCTGGTGGTGGAGGTATACCAGTAATTAGAGAGCAACATGATGGT
    TTTAAAGGTATTGATGCAGTTATAGACAAAGATAAAACAAGTGCGTTGTTGGGTGCTAAT
    ATTCAATGCGATCAATTGATTATTTTAACAGCAATTGATTATGTATATATTAATTTTAAC
    ACTGAAAACCAACAGCCTTTGAAAACAACAAATGTTGATGAATTAAAACGATATATAGAC
    GAAAATCAATTTGCAAAAGGAAGTATGTTACCAAAAATTGAAGCAGCCATATCATTTATT
    GAAAACAATCCAAAAGGAAGTGTGCTTATAACATCATTAAATGAATTAGATGCTGCCTTA
    GAGGGTAAAGTAGGTACTGTGATTAAAAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    933

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_1079 [new locus tag: NWMN_RS06115 ]
  • symbol: ArcC
  • description: carbamate kinase
  • length: 310
  • theoretical pI: 4.84797
  • theoretical MW: 33596.1
  • GRAVY: -0.157419

Function[edit source | edit]

  • reaction:
    EC 2.7.2.2?  ExPASy
    Carbamate kinaseATP + NH3 + CO2 = ADP + carbamoyl phosphate
  • TIGRFAM:
    MetabolismEnergy metabolismAmino acids and aminescarbamate kinase (TIGR00746; EC 2.7.2.2; HMM-score: 384.5)
    MetabolismAmino acid biosynthesisGlutamate familyacetylglutamate kinase (TIGR00761; EC 2.7.2.8; HMM-score: 35.9)
    MetabolismAmino acid biosynthesisGlutamate familyglutamate 5-kinase (TIGR01027; EC 2.7.2.11; HMM-score: 22.1)
    MetabolismAmino acid biosynthesisGlutamate familydelta l-pyrroline-5-carboxylate synthetase (TIGR01092; HMM-score: 16.4)
    MetabolismPurines, pyrimidines, nucleosides, and nucleotidesNucleotide and nucleoside interconversionsputative uridylate kinase (TIGR02076; EC 2.7.4.-; HMM-score: 16.3)
    cyanobactin biosynthesis protein, PatB/AcyB/McaB family (TIGR04220; HMM-score: 11.5)
  • TheSEED:  
    Amino Acids and DerivativesArginine; urea cycle, polyaminesArginine and Ornithine Degradation Carbamate kinase (EC 2.7.2.2) 
    Arginine; urea cycle, polyaminesArginine Deiminase Pathway Carbamate kinase (EC 2.7.2.2) 
    Arginine; urea cycle, polyaminesPolyamine Metabolism Carbamate kinase (EC 2.7.2.2) 
  • PFAM:
    no clan definedAA_kinase; Amino acid kinase family (PF00696; HMM-score: 99.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.17
    • Ymax_pos: 24
    • Cmax: 0.121
    • Cmax_pos: 62
    • Smax: 0.374
    • Smax_pos: 14
    • Smean: 0.221
    • D: 0.19
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]