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NCBI: 06-JUL-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2063 [new locus tag: NWMN_RS11910 ]
  • pan locus tag?: SAUPAN005507000
  • symbol: NWMN_2063
  • pan gene symbol?: ybbR
  • synonym: cdaR
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_2063 [new locus tag: NWMN_RS11910 ]
  • symbol: NWMN_2063
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2291867..2292799
  • length: 933
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGCTAGAAAGTAAATGGGGCTTGAGATTTATTGCCTTTCTTTTGGCATTGTTTTTCTTT
    TTATCTGTTAACAATGTTTTTGGAAATATCTTTAACACTGGTAATCTTGGTCAAAAGTCT
    AGTAAAACGATTCAAGATGTACCCGTTGAAATTCTTTATAACACTAAAGATTTGCATTTA
    ACAAAAGCGCCTGAAACAGTTAATGTGACTATTTCAGGACCACAATCAAAGATAATAAAA
    ATTGAAAATCCAGAAGATTTAAGAGTAGTGATTGATTTATCAAATGCTAAAGCTGGAAAA
    TATCAAGAGAAGTATCAAGTTAAAGGGTTAGCTGATGACATTCATTATTCTGTAAAACCT
    AAATTAGCAAATATTACGCTTGAAAACAAAGTAACTAAAAAGATGACAGTTCAACCTGAT
    GTAAGTCAGAGTGATATTGATCCACTTTATAAAATTACAAAGCAAGAAGTTTCACCACAA
    ACAGTTAAAGTAACAGGTGGAGAAGAACAATTGAATGATATCGCTTATTTAAAAGCCACT
    TTTAAAACTAATAAAAAGATTAATGGTGACACAAAAGATGTCGCAGAAGTAACGGCTTTT
    GATAAAAAACTGAATAAATTAAATGTATCGATTCAACCTAATGAAGTGAATTTACAAGTT
    AAAGTAGAGCCTTTTAGCAAAAAGGTTAAAGTAAATGTTAAACAGAAAGGTAGTTTAGCA
    GATGATAAAGAGTTAAGTTCGATTGATTTAGAAGATAAAGAAATTGAAATCTTCGGTAGT
    CGAGATGACTTACAAAATATAAGCGAAGTTGATGCAGAAGTAGATTTAGATGGTATTTCA
    GAATCAACTGAAAAGACTGTAAAAATCAATTTACCAGAACATGTCACTAAAGCACAACCA
    AGTGAAACGAAGGCTTATATAAATGTAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    933

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_2063 [new locus tag: NWMN_RS11910 ]
  • symbol: NWMN_2063
  • description: hypothetical protein
  • length: 310
  • theoretical pI: 6.32995
  • theoretical MW: 34624.2
  • GRAVY: -0.443871

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    no clan defined YbbR; YbbR-like protein (PF07949; HMM-score: 97.2)
    and 2 more
    E-set (CL0159) DUF3244; Domain of unknown function (DUF3244) (PF11589; HMM-score: 12.2)
    ATP_synthase (CL0255) ATP-synt_8; ATP synthase protein 8 (PF00895; HMM-score: 11.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • LocateP: N-terminally anchored (No CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: 1
    • N-terminally Anchored Score: 2
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: Signal peptide SP(Sec/SPI) length 28 aa
    • SP(Sec/SPI): 0.846006
    • TAT(Tat/SPI): 0.002594
    • LIPO(Sec/SPII): 0.02281
    • Cleavage Site: CS pos: 28-29. VFG-NI. Pr: 0.7728
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]