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NCBI: 06-JUL-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_2157 [new locus tag: NWMN_RS12455 ]
  • pan locus tag?: SAUPAN005708000
  • symbol: NWMN_2157
  • pan gene symbol?:
  • synonym:
  • product: GCN5-related N-acetyltransferase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_2157 [new locus tag: NWMN_RS12455 ]
  • symbol: NWMN_2157
  • product: GCN5-related N-acetyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 2380574..2381461
  • length: 888
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAGCATAGTTCAGTTATATGATATTACACAAATAAAATCGTTCATTGAACATTCGAAT
    TATGAATCAGCATCATACTTATATAAACTTCCTCAACAGTACAATGAAATAGATGTATTA
    ATAACCGATGCGATTGAATCACCTGGTGTATTTTCGATTAAAGAAAACGATTCAATCAAA
    GCAATCATATTGTCTTTTGCATACGATAAAAATAAATTCAAAGTCATAGGCCCTTTCGTG
    GCTGACAATTATGTATTATCTGTCGATACGTTTGAAACGCTATTTAAAGCAATGACTTCG
    AACCAACCTGACGATGCCGTCTTTAACTTTTCTTTTGAAGAAGGCATTCAACAATACAAA
    CCATTAATGAAAGTTATTCAAGCAAGTTATAACTTCACTGACTATTACATAGAAGCCCGT
    ACAAGATTAGAAGAAGATATGCACCAACCAAATATCATTCCTTATCACAAAGGGTTTTAT
    CGTGCTTTCAGCAAATTACACACAACTACATTTAAATATCAGGCACAGTCACCACAAGAT
    ATCATTGATAGTTTAGACGACCATCATCATTTGTTTTTATTTGTTAGCGAAGGTTTACTT
    AAAGGTTATTTATACCTTGAAATTGATTCACAACAGTCAATCGCCGAGATTAAATACTTC
    AGTTCTCATGTAGATTACCGTTTGAAAGGTATCGCTTTCGAGTTGCTTGCGTATGCATTG
    CAATATGCTTTTGATAATTTTGATATTAGAAAAGTTTATTTTAAAATTCGTAATAAAAAT
    AATAAACTCATCGAACGATTTAATGGTCTAGGTTTCCATATCAACTATGAGTACATTAAA
    TTCAAATTCGAATCACGTAACGTAAAAGATCAAACAATCCCTGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    888

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_2157 [new locus tag: NWMN_RS12455 ]
  • symbol: NWMN_2157
  • description: GCN5-related N-acetyltransferase
  • length: 295
  • theoretical pI: 5.82928
  • theoretical MW: 34763.1
  • GRAVY: -0.32983

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein synthesisRibosomal proteins: synthesis and modificationribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 22.9)
    UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 20)
    colanic acid biosynthesis protein WcaM (TIGR04004; HMM-score: 14.1)
  • TheSEED:  
    Acetyltransferase, GNAT family 
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 30.9)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 24)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 19.7)
    Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 12.3)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.12
    • Ymax_pos: 25
    • Cmax: 0.142
    • Cmax_pos: 25
    • Smax: 0.124
    • Smax_pos: 17
    • Smean: 0.091
    • D: 0.109
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MSIVQLYDITQIKSFIEHSNYESASYLYKLPQQYNEIDVLITDAIESPGVFSIKENDSIKAIILSFAYDKNKFKVIGPFVADNYVLSVDTFETLFKAMTSNQPDDAVFNFSFEEGIQQYKPLMKVIQASYNFTDYYIEARTRLEEDMHQPNIIPYHKGFYRAFSKLHTTTFKYQAQSPQDIIDSLDDHHHLFLFVSEGLLKGYLYLEIDSQQSIAEIKYFSSHVDYRLKGIAFELLAYALQYAFDNFDIRKVYFKIRNKNNKLIERFNGLGFHINYEYIKFKFESRNVKDQTIPE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]