NCBI: 06-JUL-2013
Contents
⊟Summary[edit source | edit]
- organism: Staphylococcus aureus Newman
- locus tag: NWMN_2360 [new locus tag: NWMN_RS13605 ]
- pan locus tag?: SAUPAN006023000
- symbol: opp1F
- pan gene symbol?: cntF
- synonym:
- product: peptide ABC transporter ATP-binding protein
⊟Genome View[edit source | edit]
⊟Gene[edit source | edit]
⊟General[edit source | edit]
- type: CDS
- locus tag: NWMN_2360 [new locus tag: NWMN_RS13605 ]
- symbol: opp1F
- product: peptide ABC transporter ATP-binding protein
- replicon: chromosome
- strand: -
- coordinates: 2597320..2598069
- length: 750
- essential: unknown other strains
⊟Accession numbers[edit source | edit]
- Gene ID: 5331447 NCBI
- RefSeq: YP_001333394 NCBI
- BioCyc:
- MicrobesOnline: 3707962 MicrobesOnline
⊟Phenotype[edit source | edit]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit source | edit]
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721ATGATTAAAATTAAAGATGTTGAAAAGTCATATCAAAGCGCACATGTTTTTAAGCGTCGT
CGAACACCTATCGTGAAAGGTGTGTCATTTGAGTGTCCAATCGGTGCGACGATTGCGATT
ATCGGAGAAAGTGGTAGCGGTAAATCGACGTTGAGTCGTATGATATTAGGTATTGAGAAA
CCGGATAAAGGTTGTGTAACCTTAAATGATCAACCGATGCATAAGAAGAAAGTGAGACGT
CATCAAATTGGTGCTGTATTTCAAGATTATACGTCATCATTACATCCATTTCAGACTGTT
AGAGAAATCTTATTTGAAGTGATGTGTCAATGTGATGGACAACCTAAAGAAGTTATGGAA
GTCCAAGCAATTACATTGTTGGAAGAAGTCGGTCTATCTAAGGCATACATGGATAAATAT
CCTAATATGTTATCAGGTGGAGAGGCGCAACGTGTTGCGATTGCGCGTGCAATATGTATT
AACCCTAAATATATTTTGTTTGATGAAGCCATTAGTTCACTCGACATGTCAATTCAAACA
CAAATATTAGATTTATTGATTCATTTACGTGAAACGCGTCAGTTGAGTTATATTTTTATC
ACACATGATATTCAAGCTGCCACGTATTTATGTGATCAATTAATTATTTTTAAAAACGGA
AAAATAGAAGAACAAATTCCGACAAGCGCATTGCATAAAAGTGACAATGCTTATACAAGA
GAATTAATAGAAAAACAACTATCATTCTAA60
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⊟Protein[edit source | edit]
⊟General[edit source | edit]
- locus tag: NWMN_2360 [new locus tag: NWMN_RS13605 ]
- symbol: Opp1F
- description: peptide ABC transporter ATP-binding protein
- length: 249
- theoretical pI: 8.12738
- theoretical MW: 28179.6
- GRAVY: -0.145382
⊟Function[edit source | edit]
- TIGRFAM: Transport and binding proteinsCations and iron carrying compoundsnickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 215)and 71 moreTransport and binding proteinsCations and iron carrying compoundsnickel import ATP-binding protein NikD (TIGR02770; HMM-score: 156.2)Transport and binding proteinsAnionssulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 153.7)Transport and binding proteinsUnknown substrateenergy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 150.7)Transport and binding proteinsAmino acids, peptides and aminesglycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 144.3)Transport and binding proteinsUnknown substrateenergy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 142.5)Transport and binding proteinsAnionsmolybdate ABC transporter, ATP-binding protein (TIGR02142; EC 3.6.3.29; HMM-score: 138)Protein fateProtein and peptide secretion and traffickinglipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 135.2)Transport and binding proteinsAmino acids, peptides and aminesputative 2-aminoethylphosphonate ABC transporter, ATP-binding protein (TIGR03265; HMM-score: 135.1)ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 134.8)Transport and binding proteinsAnionsphosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 133.1)D-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 128)Cellular processesToxin production and resistanceputative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 127.2)Transport and binding proteinsUnknown substrateputative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 127.2)Transport and binding proteinsAmino acids, peptides and aminespolyamine ABC transporter, ATP-binding protein (TIGR01187; EC 3.6.3.31; HMM-score: 125.7)Transport and binding proteinsAnionsnitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 120.5)Transport and binding proteinsOthernitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 120.5)2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 119.6)Cellular processesCell divisioncell division ATP-binding protein FtsE (TIGR02673; HMM-score: 119.5)Cellular processesBiosynthesis of natural productsNHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 115.7)Transport and binding proteinsAmino acids, peptides and aminesNHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 115.7)Transport and binding proteinsAnionsphosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 115.3)Transport and binding proteinsOtherthiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 107.8)proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 107.4)ABC exporter ATP-binding subunit, DevA family (TIGR02982; HMM-score: 105.5)Transport and binding proteinsAmino acids, peptides and aminescholine ABC transporter, ATP-binding protein (TIGR03415; HMM-score: 105.4)thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 102.4)Energy metabolismMethanogenesismethyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 102.3)Cell envelopeBiosynthesis and degradation of surface polysaccharides and lipopolysaccharidesLPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 102.2)Transport and binding proteinsOtherLPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 102.2)Transport and binding proteinsCations and iron carrying compoundscobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 99.2)Cellular processesPathogenesistype I secretion system ATPase (TIGR03375; HMM-score: 98.2)Protein fateProtein and peptide secretion and traffickingtype I secretion system ATPase (TIGR03375; HMM-score: 98.2)Cellular processesBiosynthesis of natural productsNHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 96.7)Transport and binding proteinsAmino acids, peptides and aminesNHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 96.7)Transport and binding proteinsAmino acids, peptides and aminesurea ABC transporter, ATP-binding protein UrtE (TIGR03410; HMM-score: 96.3)Transport and binding proteinsOtherdaunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 96.2)Protein fateProtein and peptide secretion and traffickingtype I secretion system ATPase (TIGR01846; HMM-score: 95.6)Transport and binding proteinsCarbohydrates, organic alcohols, and acidsABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system (TIGR03864; HMM-score: 93.8)thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 92.9)Protein fateProtein and peptide secretion and traffickingtype I secretion system ATPase (TIGR01842; HMM-score: 91)Transport and binding proteinsOtherantigen peptide transporter 2 (TIGR00958; HMM-score: 90)phosphonate C-P lyase system protein PhnL (TIGR02324; HMM-score: 87.4)ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 86)Cell envelopeBiosynthesis and degradation of surface polysaccharides and lipopolysaccharideslipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 85.9)Transport and binding proteinsOtherlipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 85.9)Cellular processesOthernodulation ABC transporter NodI (TIGR01288; HMM-score: 82.5)Transport and binding proteinsOthernodulation ABC transporter NodI (TIGR01288; HMM-score: 82.5)Protein fateProtein and peptide secretion and traffickingABC-type bacteriocin transporter (TIGR01193; HMM-score: 79.8)Protein fateProtein modification and repairABC-type bacteriocin transporter (TIGR01193; HMM-score: 79.8)Transport and binding proteinsOtherABC-type bacteriocin transporter (TIGR01193; HMM-score: 79.8)Transport and binding proteinsUnknown substrateanchored repeat-type ABC transporter, ATP-binding subunit (TIGR03771; HMM-score: 79.7)gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 75)Central intermediary metabolismPhosphorus compoundsphosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 72.8)Transport and binding proteinsCarbohydrates, organic alcohols, and acidsglucan exporter ATP-binding protein (TIGR01192; EC 3.6.3.42; HMM-score: 72.2)Protein fateProtein and peptide secretion and traffickingheme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 71.6)Transport and binding proteinsOtherheme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 71.6)Transport and binding proteinsOtherpigment precursor permease (TIGR00955; HMM-score: 70.4)lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 67)Biosynthesis of cofactors, prosthetic groups, and carriersOtherFeS assembly ATPase SufC (TIGR01978; HMM-score: 63.4)Transport and binding proteinsAmino acids, peptides and aminesurea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 60.9)Transport and binding proteinsCarbohydrates, organic alcohols, and acidsD-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 58.3)ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 56.9)Transport and binding proteinsOthermulti drug resistance-associated protein (MRP) (TIGR00957; HMM-score: 50.3)Transport and binding proteinsOtherrim ABC transporter (TIGR01257; HMM-score: 48)Transport and binding proteinsCarbohydrates, organic alcohols, and acidsperoxysomal long chain fatty acyl transporter (TIGR00954; HMM-score: 42.7)Transport and binding proteinsAmino acids, peptides and aminescyclic peptide transporter (TIGR01194; HMM-score: 40.5)Transport and binding proteinsOthercyclic peptide transporter (TIGR01194; HMM-score: 40.5)DNA metabolismDNA replication, recombination, and repairexcinuclease ABC subunit A (TIGR00630; EC 3.1.25.-; HMM-score: 36.9)Transport and binding proteinsAnionscystic fibrosis transmembrane conductor regulator (CFTR) (TIGR01271; EC 3.6.3.49; HMM-score: 32)Transport and binding proteinsOtherpleiotropic drug resistance family protein (TIGR00956; HMM-score: 24.3)Purines, pyrimidines, nucleosides, and nucleotidesSalvage of nucleosides and nucleotidesuridine kinase (TIGR00235; EC 2.7.1.48; HMM-score: 12.4)
- TheSEED: Oligopeptide transporter putative ATPase domain
- PFAM: P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 107.3)and 17 moreSMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 21.9)AAA_22; AAA domain (PF13401; HMM-score: 19.2)AAA_16; AAA ATPase domain (PF13191; HMM-score: 18.1)AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 17)AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 16)Sigma54_activat; Sigma-54 interaction domain (PF00158; HMM-score: 15.7)MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 14.3)AAA_24; AAA domain (PF13479; HMM-score: 14.2)NACHT; NACHT domain (PF05729; HMM-score: 14.1)RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 13.9)AAA_33; AAA domain (PF13671; HMM-score: 13.8)DLIC; Dynein light intermediate chain (DLIC) (PF05783; HMM-score: 13.1)SbcCD_C; Putative exonuclease SbcCD, C subunit (PF13558; HMM-score: 12.8)AAA_13; AAA domain (PF13166; HMM-score: 12.3)DUF87; Domain of unknown function DUF87 (PF01935; HMM-score: 12)NB-ARC; NB-ARC domain (PF00931; HMM-score: 11.1)AAA_23; AAA domain (PF13476; HMM-score: 10.7)
⊟Structure, modifications & interactions[edit source | edit]
- domains:
- modifications:
- cofactors:
- effectors:
- protein partners:
⊟Localization[edit source | edit]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 1.05
- Cytoplasmic Membrane Score: 8.78
- Cellwall Score: 0.08
- Extracellular Score: 0.09
- Internal Helices: 0
- LocateP: Intracellular
- Prediction by SwissProt Classification: Cytoplasmic
- Pathway Prediction: No pathway
- Intracellular Possibility: 1
- Signal Peptide Possibility: -1
- N-terminally Anchored Score: -1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- Ymax: 0.163
- Ymax_pos: 39
- Cmax: 0.117
- Cmax_pos: 42
- Smax: 0.286
- Smax_pos: 35
- Smean: 0.2
- D: 0.177
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit source | edit]
⊟Protein sequence[edit source | edit]
- MIKIKDVEKSYQSAHVFKRRRTPIVKGVSFECPIGATIAIIGESGSGKSTLSRMILGIEKPDKGCVTLNDQPMHKKKVRRHQIGAVFQDYTSSLHPFQTVREILFEVMCQCDGQPKEVMEVQAITLLEEVGLSKAYMDKYPNMLSGGEAQRVAIARAICINPKYILFDEAISSLDMSIQTQILDLLIHLRETRQLSYIFITHDIQAATYLCDQLIIFKNGKIEEQIPTSALHKSDNAYTRELIEKQLSF
⊟Experimental data[edit source | edit]
- experimentally validated: no data available
⊟Expression & Regulation[edit source | edit]
⊟Operon[edit source | edit]
⊟Regulation[edit source | edit]
- regulator:
⊟Transcription pattern[edit source | edit]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit source | edit]
- Aureolib: no data available
⊟Protein stability[edit source | edit]
- half-life: no data available
⊟Biological Material[edit source | edit]
⊟Mutants[edit source | edit]
⊟Expression vector[edit source | edit]
⊟lacZ fusion[edit source | edit]
⊟GFP fusion[edit source | edit]
⊟two-hybrid system[edit source | edit]
⊟FLAG-tag construct[edit source | edit]
⊟Antibody[edit source | edit]
⊟Other Information[edit source | edit]
You are kindly invited to share additional interesting facts.
⊟Literature[edit source | edit]
⊟References[edit source | edit]
- ↑
Artem Cherkasov, Michael Hsing, Roya Zoraghi, Leonard J Foster, Raymond H See, Nikolay Stoynov, Jihong Jiang, Sukhbir Kaur, Tian Lian, Linda Jackson, Huansheng Gong, Rick Swayze, Emily Amandoron, Farhad Hormozdiari, Phuong Dao, Cenk Sahinalp, Osvaldo Santos-Filho, Peter Axerio-Cilies, Kendall Byler, William R McMaster, Robert C Brunham, B Brett Finlay, Neil E Reiner
Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus.
J. Proteome Res.: 2011, 10(3);1139-50
[PubMed:21166474] [WorldCat.org] [DOI] (I p)
⊟Relevant publications[edit source | edit]