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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS00270 [old locus tag: NWMN_0046 ]
  • pan locus tag?: SAUPAN000891000
  • symbol: NWMN_RS00270
  • pan gene symbol?:
  • synonym:
  • product: AraC family transcriptional regulator

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS00270 [old locus tag: NWMN_0046 ]
  • symbol: NWMN_RS00270
  • product: AraC family transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 58854..61052
  • length: 2199
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (58854..61052) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

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    1021
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    ATGTCAGATTTCAAAAGGCTCAATAGTTTAATGATTGGTTTTGTTATTAAAGGTGAGGCA
    CACATTTATGATGAAAATAATATGACGCAATGCAACAGTGGCGACATTTTCATCATTAAC
    CACCGCGACTTGTATCGATTTCAACTTCAACAAGATGGCATCATATGTTATATCCAATTC
    CAAATGAAATATTTAGCAGACAAGTTTGATGATGTGCATTGTCTATATTTTCACTTAACA
    GATGCGACCACAACAAAGAATATACATCAACTGAGAAATATAATGGCAAGACTGGTTTCA
    ACACATATCCGACATAATGAGTTGTCTAAATTGACTGAGCAACAACTTGTGATTCAGTTG
    CTTATGCATATGATTCATTATGTCCCGCGTACATATCATTCGAACCAAAGTATCTTAAAT
    GATGATAAAGTGAATCAAGTATGCGACTATATCGAGTTACATTTTCATGAAGATTTAAGC
    CTTTCAGAATTAAGCGAATACGTTGGGTGGTCAGAGAGCCATCTGTCTAAAAAGTTTACA
    GAATCGCTAGGTGTAGGATTCCATCATTTCTTAAATACGACGCGAATTGAGCATGCGAAA
    CTCGATTTGACATACACAGATGAAACCATTACTGATATTGCATTGCAAAATGGCTTTTCA
    AGTGCAGCGAGCTTTGCGAGAACATTTAAACACTTTACGCATCAAACACCTAAACAATAT
    CGAGGTGATCGTCCAGCAATCACTGAAAACCAGCAATCGGCACAACATGATTATCACGAC
    CGTGAATTGATATTACTTTTAAATGACTACATTGAAGAAATGAATCATTTTATTGAAGAT
    ATTGAAAAGATGAACTATAAAGAGATTGCCTTTCAACCAACCAATCACCAACTAAATCAA
    TTTAATCATATTATTCAAGTGGGCTATTTGAGGAATTTGCTCAATACACAGTATCAATCA
    CAGTTGCTTACATGTCATCATGATTTTCAAGTCAATGAAGTATTAGCATATGATGTGATT
    CCATATATCATGAAAAAGCTCAATGCGCCATTCACGTATGATGCAGAAATTTCGAATATA
    TTTTATGATATTGATTTGTGTTTAGACTTTTTATTAGATCATAACTTTAGTTTGACCATG
    CATTTGGATCAGTATGACTCACGTGATTATATCGATGCATTTAAAATTTTTATCCATCAC
    GTTGCCCTGCATGTCAGTCATAGAAAAGATTTGAAGTTCAACTTGTATGTGACGACATTG
    CACACGTCTTTGATTGAAATGATTGATTATTTTAAAGCATTATTCCCTAATGGTGGCTTG
    TACATTCACTTAGATCAAGCTACGGAAAGACATCTACCATTATTGAAACGACTTGAGCCA
    CACATCGACCATTTTGTATTTGATGCCAATTCAAATGACGCTGTTGATTTTAATAAAATG
    AATGATGATGAATTTAAAACCGCGAGTCAAATGATTATTAATAAAACGAATTACCTTATC
    GACTTAATGCATCGTCATCGCCTAAAGCGTCCACTCATTTTACTCAATTGGAATACATTG
    ACGGGTGATACATTTATTACAAACGGCGAATATTTTAGAGGTGGTATCATCATTGAGCAA
    TTATTAAAATTAAGTTCTAAAGTAGAGGGTATCGGGTATAGGTTGAATTATGATTTGCAC
    GTCAGTCATTGTAAAAATGAACGGGATTATATGAATTCTATTGAACTATTTCATCAATAT
    AATGGAAAACGTCCGGTCTATTTCACGGCATTGCTATTTAATAAATTAACAAGCAATATT
    TTGTATTCTGATGATACATGTATTGTCACGGGGACTGATTCAAATTTTCAAATATTGTTA
    TATGATGCAAAGCATTTTAATCCGTACTTAGCGTTGGACAATCAAATGAATATGCGTGCG
    ACGGAAATGATTCATTTGAACATTAATGCCCTGGAAGAAGGTATGTATAAGATTAAACAT
    TTTACCTTAGATAAAGAAAATGGTGCGTTATTTAATCTTTGGCGCAAACATCATACGATA
    CATGGCATGGACAAGGACTCTATAGATTACGTTAATCGAATGAGTTTTCCGAAATTAGAA
    GTATATGATATAGATATCACGGACACACTGGCATTAAACATTAAAATGATTACGAATGGG
    ATTCACTTAATTGAAGTAAAACGTTACCCAAGTTCATAA
    60
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Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS00270 [old locus tag: NWMN_0046 ]
  • symbol: NWMN_RS00270
  • description: AraC family transcriptional regulator
  • length: 732
  • theoretical pI: 6.43642
  • theoretical MW: 86304.5
  • GRAVY: -0.359563

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    YSIRK-targeted surface antigen transcriptional regulator (TIGR04094; HMM-score: 58.8)
    4-hydroxyphenylacetate catabolism regulatory protein HpaA (TIGR02297; HMM-score: 45.2)
  • TheSEED:
  • PFAM:
    HTH (CL0123) HTH_18; Helix-turn-helix domain (PF12833; HMM-score: 77.7)
    HTH_AraC; Bacterial regulatory helix-turn-helix proteins, AraC family (PF00165; HMM-score: 39.6)
    Cupin (CL0029) AraC_binding; AraC-like ligand binding domain (PF02311; HMM-score: 14.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.164
    • Ymax_pos: 23
    • Cmax: 0.125
    • Cmax_pos: 23
    • Smax: 0.378
    • Smax_pos: 20
    • Smean: 0.188
    • D: 0.173
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI:
  • RefSeq: WP_078061238 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MSDFKRLNSLMIGFVIKGEAHIYDENNMTQCNSGDIFIINHRDLYRFQLQQDGIICYIQFQMKYLADKFDDVHCLYFHLTDATTTKNIHQLRNIMARLVSTHIRHNELSKLTEQQLVIQLLMHMIHYVPRTYHSNQSILNDDKVNQVCDYIELHFHEDLSLSELSEYVGWSESHLSKKFTESLGVGFHHFLNTTRIEHAKLDLTYTDETITDIALQNGFSSAASFARTFKHFTHQTPKQYRGDRPAITENQQSAQHDYHDRELILLLNDYIEEMNHFIEDIEKMNYKEIAFQPTNHQLNQFNHIIQVGYLRNLLNTQYQSQLLTCHHDFQVNEVLAYDVIPYIMKKLNAPFTYDAEISNIFYDIDLCLDFLLDHNFSLTMHLDQYDSRDYIDAFKIFIHHVALHVSHRKDLKFNLYVTTLHTSLIEMIDYFKALFPNGGLYIHLDQATERHLPLLKRLEPHIDHFVFDANSNDAVDFNKMNDDEFKTASQMIINKTNYLIDLMHRHRLKRPLILLNWNTLTGDTFITNGEYFRGGIIIEQLLKLSSKVEGIGYRLNYDLHVSHCKNERDYMNSIELFHQYNGKRPVYFTALLFNKLTSNILYSDDTCIVTGTDSNFQILLYDAKHFNPYLALDNQMNMRATEMIHLNINALEEGMYKIKHFTLDKENGALFNLWRKHHTIHGMDKDSIDYVNRMSFPKLEVYDIDITDTLALNIKMITNGIHLIEVKRYPSS

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS00270 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]