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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS02145 [old locus tag: NWMN_0379 ]
  • pan locus tag?: SAUPAN001995000
  • symbol: NWMN_RS02145
  • pan gene symbol?: pbuX
  • synonym:
  • product: xanthine permease

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS02145 [old locus tag: NWMN_0379 ]
  • symbol: NWMN_RS02145
  • product: xanthine permease
  • replicon: chromosome
  • strand: +
  • coordinates: 426645..427913
  • length: 1269
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (426645..427913) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAAAAATTTAATCCTAAGTGTTCAACATCTTTTAGCTATGTACGCAGGTGCTATCTTA
    GTTCCAATCATTGTTGGTACAAGTTTGAAGTTTACACCTGAACAAATCGCTTACTTAGTT
    ACAGTAGATATATTTATGTGTGGGGTTGCCACATTTTTACAAGCCAATAAAGTAACAGGA
    ACAGGATTACCAATCGTTCTTGGATGTACATTCACGGCTGTTGCGCCCATGATTTTAATT
    GGTCAAACGAAAGGAATAGATGTACTTTATGGTTCGCTATTTTTATCAGGGATATTAGTT
    ATTATCATCGCGCCTTTCTTTTCACATCTTGTAAAATTCTTCCCACCAGTAGTAACGGGT
    AGTGTTGTTACTATCATTGGTATCAATTTAATGCCAGTAGCAATGAATTACTTAGCTGGA
    GGTCAAGGTGCAAAGGACTATGGAGATGTTAAGAACATTTTGTTAGGTTTAATGACATTA
    ATCATTATTCTTCTTTTACAAAGATTCACAACTGGATTTATTAAGAGTATTGCCATATTA
    ATTGGACTCGTTTTAGGAACGATAGGTGCTGGCTTACTTGGGATGGTCGATATTAATCAA
    GTCAATCATGCCGGTTGGTTAGGCATCCCAGTGCCGTTTAGATTCTCTGGATTTAGCTTT
    GATGTGACATCGACGTTAGTGTTCTTTATTGTAGCTATCGTTAGTTTAATTGAGTCGACA
    GGTGTCTATCATGCGTTAAGTGAAATTACCGGTAAGAAGTTAGAAAGAAAAGATTTTCGT
    AAAGGTTATACTGCGGAAGGTCTAGCGATAGTGTTAGGTTCTATATTCAATTCATTTCCG
    TATACAGCCTATTCGCAAAATGTAGGACTTGTTTCTTTATCCGGCGCTAAGAAAAACAAT
    GTTATATACGGCATGGTCGTGTTATTACTTATATGTGGTTGTATACCTAAGCTTGGCGCA
    TTAGCAAATATCATACCGCTACCTGTGTTAGGCGGTGCGATGATAGCTATGTTTGGCATG
    GTAATGGCATATGGTGTTAGTATATTAGGACATATCGATTTTAAAAATCAAAACAATTTA
    TTAATTATCGCTGTATCAGTAGGATTAGGTACTGGTATAAGCGCTGTACCACAAGCATTT
    AAAGGTTTAGGTGAACAATTTGCATGGTTGACTCAAAACGGAATTGTTTTAGGCGCAATC
    TCTGCAATTATTCTTAATTTCTTTTTTAATGGAATAAAGTATAAACAAACGGAAGAAAAT
    GTGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1269

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS02145 [old locus tag: NWMN_0379 ]
  • symbol: NWMN_RS02145
  • description: xanthine permease
  • length: 422
  • theoretical pI: 9.51484
  • theoretical MW: 44803.4
  • GRAVY: 0.935782

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    xanthine permease (TIGR03173; HMM-score: 508.8)
    MetabolismTransport and binding proteinsNucleosides, purines and pyrimidinesuracil-xanthine permease (TIGR00801; HMM-score: 414.1)
    pyrimidine utilization transport protein G (TIGR03616; HMM-score: 118.1)
    putative glycosyltransferase, exosortase G-associated (TIGR03111; HMM-score: 9.7)
  • TheSEED:
  • PFAM:
    APC (CL0062) Xan_ur_permease; Permease family (PF00860; HMM-score: 352)
    no clan definedChloroplast_duf; Petal formation-expressed (PF14476; HMM-score: 9.3)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.195
    • Ymax_pos: 16
    • Cmax: 0.155
    • Cmax_pos: 40
    • Smax: 0.435
    • Smax_pos: 6
    • Smean: 0.346
    • D: 0.253
  • predicted transmembrane helices (TMHMM): 13

Accession numbers[edit source | edit]

  • GI: 446715686 NCBI
  • RefSeq: WP_000793009 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILLLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS02145 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]