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NCBI: 02-MAR-2017

Summary[edit | edit source]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS04560 [old locus tag: NWMN_0806 ]
  • pan locus tag?: SAUPAN003034000
  • symbol: NWMN_RS04560
  • pan gene symbol?: dltD
  • synonym:
  • product: D-alanyl-lipoteichoic acid biosynthesis protein DltD

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: NWMN_RS04560 [old locus tag: NWMN_0806 ]
  • symbol: NWMN_RS04560
  • product: D-alanyl-lipoteichoic acid biosynthesis protein DltD
  • replicon: chromosome
  • strand: +
  • coordinates: 893984..895159
  • length: 1176
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Location: NC_009641 (893984..895159) NCBI
  • BioCyc:
  • MicrobesOnline: see NWMN_0806

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAAATTAAAACCTTTTTTACCCATTTTAATTAGTGGAGCGGTATTCATTGTCTTTCTA
    TTATTACCTGCTAGTTGGTTTACAGGATTAGTAAATGAAAAGACTGTAGAAGATAATAGA
    ACTTCATTGACAGATCAAGTACTAAAAGGCACACTCATTCAAGATAAGTTATACGAATCA
    AACAAGTATTATCCTATATACGGCTCTAGTGAATTAGGTAAAGATGACCCATTTAATCCT
    GCAATTGCATTAAATAAGCATAACGCCAACAAAAAAGCATTCTTATTAGGTGCTGGTGGT
    TCTACAGACTTAATTAACGCAATTGAACTTGCATCACAGTATGATAAATTAAAAGGTAAG
    AAATTAACATTTATTATTTCACCACAATGGTTTACAAACCATGGTTTAACGAATCAAAAC
    TTTGATGCTCGTATGTCTCAAACTCAAATTAATCAAATGTTCCAGCAGAAAAACATGTCT
    ACTGAATTAAAACGTCGTTATGCACAACGTTTATTACAGTTTCCACATGTACACAATAAA
    GAATACTTGAAATCTTATGCTAAAAACCCTAAAGAAACTAAAGATAGTTATATTTCTGGT
    TTTAAAGAGAATCAATTGATTAAAATAGAAGCGATTAAATCATTGTTTGCAATGGATAAA
    TCTCCATTAGAACATGTTAAACCTGCTACAAAACCAGACGCTTCTTGGGATGAGATGAAA
    CAAAAAGCAGTTGAAATTGGTAAAGCTGATACTACATCGAATAAATTTGGTATTAGAGAT
    CAATACTGGAAATTAATTCAAGAAAGTAAGCGTAAAGTTAGACGTGACTACGAATTCAAT
    GTTAATTCTCCAGAATTCCAAGATTTAGAATTACTTGTAAAAACAATGCGTGCTGCTGGT
    GCAGATGTTCAATATGTAAGTATTCCATCAAACGGTGTATGGTATGACCACATTGGTATC
    GATAAAGAACGTCGTCAAGCAGTTTATAAAAAAATCCATTCTACTGTTGTAGATAATGGT
    GGTAAAATTTACGATATGACTGATAAAGATTATGAAAAATATGTTATCAGTGATGCCGTA
    CACATCGGTTGGAAAGGTTGGGTTTATATGGATGAGCAAATTGCGAAACATATGAAAGGT
    GAACCACAACCTGAAGTAGATAAACCTAAAAATTAA
    60
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    420
    480
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    840
    900
    960
    1020
    1080
    1140
    1176

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: NWMN_RS04560 [old locus tag: NWMN_0806 ]
  • symbol: NWMN_RS04560
  • description: D-alanyl-lipoteichoic acid biosynthesis protein DltD
  • length: 391
  • theoretical pI: 9.73378
  • theoretical MW: 44960.1
  • GRAVY: -0.63376

Function[edit | edit source]

  • TIGRFAM:
    D-alanyl-lipoteichoic acid biosynthesis protein DltD (TIGR04092; HMM-score: 376.7)
  • TheSEED: data available for COL, N315, NCTC8325, USA300_FPR3757
  • PFAM:
    SGNH_hydrolase (CL0264) DltD; DltD protein (PF04914; HMM-score: 346.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helix: 1
  • LocateP:
  • SignalP: Signal peptide SP(Sec/SPI) length 33 aa
    • SP(Sec/SPI): 0.459943
    • TAT(Tat/SPI): 0.007007
    • LIPO(Sec/SPII): 0.115123
    • Cleavage Site: CS pos: 33-34. VNE-KT. Pr: 0.0477
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKLKPFLPILISGAVFIVFLLLPASWFTGLVNEKTVEDNRTSLTDQVLKGTLIQDKLYESNKYYPIYGSSELGKDDPFNPAIALNKHNANKKAFLLGAGGSTDLINAIELASQYDKLKGKKLTFIISPQWFTNHGLTNQNFDARMSQTQINQMFQQKNMSTELKRRYAQRLLQFPHVHNKEYLKSYAKNPKETKDSYISGFKENQLIKIEAIKSLFAMDKSPLEHVKPATKPDASWDEMKQKAVEIGKADTTSNKFGIRDQYWKLIQESKRKVRRDYEFNVNSPEFQDLELLVKTMRAAGADVQYVSIPSNGVWYDHIGIDKERRQAVYKKIHSTVVDNGGKIYDMTDKDYEKYVISDAVHIGWKGWVYMDEQIAKHMKGEPQPEVDKPKN

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]