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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS04960 [old locus tag: NWMN_0886 ]
  • pan locus tag?: SAUPAN003193000
  • symbol: NWMN_RS04960
  • pan gene symbol?: ltaA
  • synonym:
  • product: MFS transporter

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS04960 [old locus tag: NWMN_0886 ]
  • symbol: NWMN_RS04960
  • product: MFS transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 982491..983699
  • length: 1209
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (982491..983699) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGAAAGGTTCCTTTATATGCAAGATTCTTCGTTAAATAATTACGCTAATCATAAAAAT
    TTCATTTTAATGCTTATTATCTTATTTTTAATGGAATTTGCGAGAGGCATGTATATCCTA
    AGCTATATTAATTTCTTGCCAACAGTTACATCCATTGCTGTAGCAATAACGTCTCTAGCA
    TTTTCAATACATTTTATTGCTGATGCATCTACAAACTTTGTTATAGGATTTTTACTGAAA
    AAATTCGGCACAAAAATCGTTTTAACGACTGGATTTATTTTAGCATTTACAAGTTTATTT
    TTAGTTATTTGGTTTCCAGCATCACCTTTTGTAATCATATTTAGTGCTATGATGCTCGGT
    ATTGCAGTTAGTCCTATTTGGGTCATTATGTTATCCAGTGTTGAAGAAGATAAACGTGGC
    AAACAAATGGGCTATGTTTATTTTTCATGGTTGTTAGGCCTATTGGTAGGTATGGTTTTT
    ATGAATCTACTTATCAAAGTGCACCCAACACGCTTTGCCTTCATGATGTCTTTAGTCGTT
    TTAATTGCATGGATATTATATTATTTTGTCGATGTAAAGTTAACAAATTATAATACTCGT
    CCAGTTAAAGCTCAATTGAGACAAATTGTTGATGTGACAAAGCGCCATTTATTGTTGTTC
    CCTGGTATTCTTTTACAAGGTGCCGCAATTGCTGCCCTAGTTCCTATATTACCAACATAT
    GCTACTAAGGTTATTAACGTAAGCACAATTGAATATACTGTTGCAATCATTATTGGTGGT
    ATCGGCTGTGCAGTTTCGATGCTATTTTTATCGAAACTAATAGATAACCGCAGCAGAAAC
    TTTATGTATGGTGTTATTCTAAGCGGATTTATTTTATACATGATATTAATTTTTACTCTA
    TCTATGATTGTTAATATTCACATCTTGTGGATTATCGCTTTAGCTATCGGTCTAATGTAT
    GGCATCTTATTACCAGCATGGAATACCTTTATGGCACGATTTATCAAATCAGATGAACAA
    GAAGAAACTTGGGGTGTTTTTAATAGTATCCAAGGATTCGGCTCAATGATAGGGCCATTA
    TTTGGCGGATTAATTACACAATTTACCAACAATTTAAACAATACATTTTATTTCTCGGCA
    TTAATCTTTTTAGTCTTAGCTGTATTTTATGGAAGCTACTTTATAGTAAATAGAGAAAAA
    GCTAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1209

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS04960 [old locus tag: NWMN_0886 ]
  • symbol: NWMN_RS04960
  • description: MFS transporter
  • length: 402
  • theoretical pI: 9.88498
  • theoretical MW: 45457.4
  • GRAVY: 0.936318

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    multidrug resistance protein (TIGR00880; HMM-score: 49.9)
    MetabolismTransport and binding proteinsCations and iron carrying compoundsH+ Antiporter protein (TIGR00900; HMM-score: 27.9)
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidsD-galactonate transporter (TIGR00893; HMM-score: 19.5)
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidsphosphoglycerate transporter family protein (TIGR00881; HMM-score: 10)
    drug resistance transporter, Bcr/CflA subfamily (TIGR00710; HMM-score: 6.7)
    MetabolismTransport and binding proteinsOtherglycerol-3-phosphate transporter (TIGR00712; HMM-score: 5.2)
  • TheSEED:
  • PFAM:
    MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 132)
    MFS_1_like; MFS_1 like family (PF12832; HMM-score: 15.5)
    ATG22; Vacuole effluxer Atg22 like (PF11700; HMM-score: 7.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.222
    • Ymax_pos: 70
    • Cmax: 0.348
    • Cmax_pos: 70
    • Smax: 0.173
    • Smax_pos: 66
    • Smean: 0.088
    • D: 0.17
  • predicted transmembrane helices (TMHMM): 12

Accession numbers[edit source | edit]

  • GI:
  • RefSeq: WP_001795545 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MERFLYMQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLAFSIHFIADASTNFVIGFLLKKFGTKIVLTTGFILAFTSLFLVIWFPASPFVIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVFMNLLIKVHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTYATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTLSMIVNIHILWIIALAIGLMYGILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPLFGGLITQFTNNLNNTFYFSALIFLVLAVFYGSYFIVNREKAK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS04960 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]