NCBI: 02-MAR-2017

⊟Summary

• organism: Staphylococcus aureus Newman
• locus tag: NWMN_RS08110 [old locus tag: NWMN_1437 ]
• pan locus tag^?: SAUPAN004110000
• symbol: NWMN_RS08110
• pan gene symbol^?: lipM
• synonym:
• product: octanoyltransferase LipM

⊟Gene

⊟General

• type: CDS
• locus tag: NWMN_RS08110 [old locus tag: NWMN_1437 ]
• symbol: NWMN_RS08110
• product: octanoyltransferase LipM
• replicon: chromosome
• strand: -
• coordinates: 1607046..1607876
• length: 831
• essential: unknown

⊟Accession numbers

• Location: NC_009641 (1607046..1607876) NCBI
• BioCyc:
• MicrobesOnline:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  ATGACTGAAACTTGGAATTTTATTAATACAGGAAGTAAAGACCCATATTATAATATGGCA
  ATGGATGAAGCGTTATTAAATTTTGTCTCTAGAGGTGAAATTGATCCAGTTATACGTTTT
  TACACATGGAATCCTGCAACATTATCAATAGGGTATTTCCAAAGGCTACAAAAAGAAATT
  GATATTGATAAGGTTAAAGAGAAAGGTTTTGGTCTCGTAAGGCGTCAAACTGGTGGCCGT
  GGGGTGCTACATGATAAAGAGTTAACTTACAGTGTGATTGTGCCTGAATCGCATCCGAAT
  ATGCCTTCTACAGTTACAGAAGCGTACAGAGTGATTTCACAAGGATTATTAGAAGGATTT
  AAAAACTTAGGATTTGATACTTATTTTGCGGTACCTAAAACGCCTGAAGAGCGTCAAAAA
  TTAAAACAACCTCGAAGTTCAGTGTGTTTTGATGCACCAAGTTGGTATGAGCTAGTTGTT
  GAAGGCCGTAAGATTGCTGGGAGTGCTCAAACGAGACAAAAGGGCGTAATCCTCCAACAC
  GGTTCGATTTTACAAGATATTGATATTGATGAACTGTTTGATATGTTTATTTATAAAAAT
  GAAAGATTAAAATTAAAAATGAAAGAGGCATTCGTTGAAAAAGCAGTTGCCATCAATGAT
  ATTTCAGATGAACACATTACTATTAGTCAAATGGAAGAAGCTTTCGAGAAAGGTTTTAAG
  AAAGGTTTAAATATAGAATTAAAGCCACTTGAATTAACAGAAGCTCAATTGGCAGAAGTG
  GAAGAATTAACTGAAAAATATCGTTCAGATGAATGGATGTTTAGAAAGTAG
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  831
  

⊟Protein

⊟General

• locus tag: NWMN_RS08110 [old locus tag: NWMN_1437 ]
• symbol: NWMN_RS08110
• description: octanoyltransferase LipM
• length: 276
• theoretical pI: 5.15375
• theoretical MW: 31881.2
• GRAVY: -0.473913

⊟Function

• reaction:
  EC 2.3.1.181?  ExPASy
  Lipoyl(octanoyl) transferaseOctanoyl-[acyl-carrier-protein] + protein = protein N⁶-(octanoyl)lysine + [acyl-carrier-protein]
• TIGRFAM:
  Genetic information processingProtein fateProtein modification and repairlipoyltransferase and lipoate-protein ligase (TIGR00545; HMM-score: 101)
• TheSEED:
• PFAM:
  tRNA_synt_II (CL0040) BPL_LplA_LipB; Biotin/lipoate A/B protein ligase family (PF03099; HMM-score: 95.4)

⊟Structure, modifications & interactions

• domains:
• modifications:
• cofactors:
• effectors:
• protein partners:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• LocateP:
• SignalP: no predicted signal peptide
  • Ymax: 0.103
  • Ymax_pos: 69
  • Cmax: 0.127
  • Cmax_pos: 21
  • Smax: 0.123
  • Smax_pos: 64
  • Smean: 0.069
  • D: 0.09
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 446063254 NCBI
• RefSeq: WP_000141109 NCBI
• UniProt:

⊟Protein sequence

• MTETWNFINTGSKDPYYNMAMDEALLNFVSRGEIDPVIRFYTWNPATLSIGYFQRLQKEIDIDKVKEKGFGLVRRQTGGRGVLHDKELTYSVIVPESHPNMPSTVTEAYRVISQGLLEGFKNLGFDTYFAVPKTPEERQKLKQPRSSVCFDAPSWYELVVEGRKIAGSAQTRQKGVILQHGSILQDIDIDELFDMFIYKNERLKLKMKEAFVEKAVAINDISDEHITISQMEEAFEKGFKKGLNIELKPLELTEAQLAEVEELTEKYRSDEWMFRK

⊟Experimental data

• experimentally validated: no data available

⊟Expression & Regulation

⊟Operon

• NWMN_RS08110 no polycistronic organisation predicted

⊟Regulation

• sigma factor:
• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Other Information

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