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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS09810 [old locus tag: NWMN_1741 ]
  • pan locus tag?: SAUPAN004782000
  • symbol: NWMN_RS09810
  • pan gene symbol?: airS
  • synonym:
  • product: sensor histidine kinase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS09810 [old locus tag: NWMN_1741 ]
  • symbol: NWMN_RS09810
  • product: sensor histidine kinase
  • replicon: chromosome
  • strand: -
  • coordinates: 1942194..1943306
  • length: 1113
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (1942194..1943306) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGAACAAAGGACGCGACTAGCTTTATTAAAAGAGATTGCCGAATTTTTAAACGAAGAA
    ACTGAAATGTATAGCATGACCCAAGGTGCGTTAAAATATTTAATTGAGGGCAGTAATTTC
    ACGACAGGCTGGATATTTTTCATCAATAGCGTAGGTGAACATGAACTTGTATCACATGTG
    GCTCTACCACAATCTTTGACAGCAGACCACTGTCACTATATTAAAGATGGGTCTTGTTGG
    TGTGTGAAAGCATTTAATCAACGTAGGCTAATGAAAGCGTCGAATATCGTCAATTGTTCT
    CGTATTAACTTAGCCTCTAAAGCATTTCCTAGCCAAAATGACAATATTACACATCATGCA
    ACGGTACCACTTAAATCGGGTCAAGAACAATTCGGCATTTTAAATGTAGCGTCTCCAAAT
    ACTGAAATATATAGCGATGAAGATTTAGAGTTGCTAGAGTCTGTCGCATTTCAATTAGGG
    TCAGCCATCAAACGTATTTATTTAACAGACCGTGAAAAAGAAGCGGCAAAAATTAATGAA
    CGTAATCGTTTAGCTAGAGATTTACATGATTCAGTAAATCAAATGTTATTTTCTGTAAAA
    CTAACAGCACATGCTGCGTATGGCATGTCAAACGAATCCATCGCTAAACAAGCATTCAAG
    ACGATTGAGGAAACGAGTCAAAATGCCGTTAATGAAATGCGTGCATTGATTTGGCAACTT
    AAGCCAGTTGGACTTGAGCAAGGTTTAATTCATGCTTTGACAGCATATAGTAAATTAATG
    CATATACAATTAAATGTAAATGTAGAAGGTTTAATCGATTTATCTAATGAAATCGAAGAA
    AACATATACAGAGCATTACAAGAGTGTATTAATAATGTTAAGAAACATGCTGATACGAAT
    AAAATGGATCTTACATTAAAACAAATGAACGATATACTATATATTGACGTGATTGATTAT
    GGTCAAGGATTTGAGATCGATAATGTTCAGATAGCTTCATCACACGGTATTAATAACATA
    AAACAAAGAGTTAAATTATTAAGAGGTAAAGTGACCTTTCATTCTCAGCCAACAAAGGGT
    ACACAAATACAATTCACAATTCCTATAAAATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1113

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS09810 [old locus tag: NWMN_1741 ]
  • symbol: NWMN_RS09810
  • description: sensor histidine kinase
  • length: 370
  • theoretical pI: 6.70362
  • theoretical MW: 41880.5
  • GRAVY: -0.293784

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein fateProtein and peptide secretion and traffickingputative PEP-CTERM system histidine kinase (TIGR02916; EC 2.7.13.3; HMM-score: 34.6)
    Signal transductionSignal transductionTwo-component systemsputative PEP-CTERM system histidine kinase (TIGR02916; EC 2.7.13.3; HMM-score: 34.6)
    MetabolismCentral intermediary metabolismNitrogen fixationNif-specific regulatory protein (TIGR01817; HMM-score: 25.5)
    Signal transductionRegulatory functionsDNA interactionsNif-specific regulatory protein (TIGR01817; HMM-score: 25.5)
    anti-sigma B factor (TIGR01924; EC 2.7.11.1; HMM-score: 12.6)
  • TheSEED:
  • PFAM:
    His_Kinase_A (CL0025) HisKA_3; Histidine kinase (PF07730; HMM-score: 64.1)
    GAF (CL0161) GAF_2; GAF domain (PF13185; HMM-score: 53)
    GAF_3; GAF domain (PF13492; HMM-score: 35.8)
    His_Kinase_A (CL0025) HATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (PF02518; HMM-score: 29.2)
    GAF (CL0161) GAF; GAF domain (PF01590; HMM-score: 27.8)
    no clan definedFlu_M1_C; Influenza Matrix protein (M1) C-terminal domain (PF08289; HMM-score: 16.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.116
    • Ymax_pos: 11
    • Cmax: 0.115
    • Cmax_pos: 25
    • Smax: 0.21
    • Smax_pos: 1
    • Smean: 0.118
    • D: 0.117
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446360112 NCBI
  • RefSeq: WP_000437967 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGWIFFINSVGEHELVSHVALPQSLTADHCHYIKDGSCWCVKAFNQRRLMKASNIVNCSRINLASKAFPSQNDNITHHATVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLGSAIKRIYLTDREKEAAKINERNRLARDLHDSVNQMLFSVKLTAHAAYGMSNESIAKQAFKTIEETSQNAVNEMRALIWQLKPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSNEIEENIYRALQECINNVKKHADTNKMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASSHGINNIKQRVKLLRGKVTFHSQPTKGTQIQFTIPIK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS09810 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]